Find Alatrofloxacin manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Alatrofloxacin [inn], 146961-76-4, 7qvv6i50dt, 157182-32-6, Alatrofloxacin (inn), 7-((1r,5s,6s)-6-((s)-2-((s)-2-aminopropanamido)propanamido)-3-azabicyclo[3.1.0]hexan-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Molecular Formula
C26H25F3N6O5
Molecular Weight
558.5  g/mol
InChI Key
UUZPPAMZDFLUHD-LZGARRQBSA-N
FDA UNII
7QVV6I50DT

Alatrofloxacin
Alatrofloxacin is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. It was withdrawn from the U.S. market in 2001.
1 2D Structure

Alatrofloxacin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-[(1R,5S)-6-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
2.1.2 InChI
InChI=1S/C26H25F3N6O5/c1-10(30)24(37)31-11(2)25(38)32-20-14-7-34(8-15(14)20)23-18(29)6-13-21(36)16(26(39)40)9-35(22(13)33-23)19-4-3-12(27)5-17(19)28/h3-6,9-11,14-15,20H,7-8,30H2,1-2H3,(H,31,37)(H,32,38)(H,39,40)/t10-,11-,14-,15+,20?/m0/s1
2.1.3 InChI Key
UUZPPAMZDFLUHD-LZGARRQBSA-N
2.1.4 Canonical SMILES
CC(C(=O)NC(C)C(=O)NC1C2C1CN(C2)C3=C(C=C4C(=O)C(=CN(C4=N3)C5=C(C=C(C=C5)F)F)C(=O)O)F)N
2.1.5 Isomeric SMILES
C[C@@H](C(=O)N[C@@H](C)C(=O)NC1[C@H]2[C@@H]1CN(C2)C3=C(C=C4C(=O)C(=CN(C4=N3)C5=C(C=C(C=C5)F)F)C(=O)O)F)N
2.2 Other Identifiers
2.2.1 UNII
7QVV6I50DT
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Alatrofloxacin Mesylate

2. Cp 116,517

3. Cp 116517

4. Cp-116,517

5. Cp-116517

6. Trovan

2.3.2 Depositor-Supplied Synonyms

1. Alatrofloxacin [inn]

2. 146961-76-4

3. 7qvv6i50dt

4. 157182-32-6

5. Alatrofloxacin (inn)

6. 7-((1r,5s,6s)-6-((s)-2-((s)-2-aminopropanamido)propanamido)-3-azabicyclo[3.1.0]hexan-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic Acid

7. 7-[(1r,5s)-6-[[(2s)-2-[[(2s)-2-aminopropanoyl]amino]propanoyl]amino]-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic Acid

8. Unii-7qvv6i50dt

9. Alatrofloxacin [vandf]

10. Schembl140567

11. Schembl7616277

12. Alatrofloxacin [who-dd]

13. Chembl1201197

14. Dtxsid4057893

15. Chebi:135829

16. Zinc100067477

17. Zinc245224310

18. Db09335

19. Hy-16035

20. L-alaninamide, L-alanyl-n-((1alpha,5alpha,6alpha)-3-(6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl)-3-azabicyclo(310)hex-6-yl)-

21. L-alaninamide, L-alanyl-n-(3-(6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl)-3-azabicyclo(310)hex-6-yl)-, (1alpha,5alpha,6alpha)-

22. Cs-0006126

23. D07562

24. 7-((1r,5s,6s)-6-((s)-2-((s)-2-aminopropionamido)propionamido)-3-azabicyclo(3.1.0)hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid

2.4 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 558.5 g/mol
Molecular Formula C26H25F3N6O5
XLogP3-0.2
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count12
Rotatable Bond Count7
Exact Mass558.18385241 g/mol
Monoisotopic Mass558.18385241 g/mol
Topological Polar Surface Area158 Ų
Heavy Atom Count40
Formal Charge0
Complexity1080
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Infective Agents

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)


Topoisomerase II Inhibitors

Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. (See all compounds classified as Topoisomerase II Inhibitors.)


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Looking for 146961-76-4 / Alatrofloxacin API manufacturers, exporters & distributors?

Alatrofloxacin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Alatrofloxacin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Alatrofloxacin manufacturer or Alatrofloxacin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Alatrofloxacin manufacturer or Alatrofloxacin supplier.

PharmaCompass also assists you with knowing the Alatrofloxacin API Price utilized in the formulation of products. Alatrofloxacin API Price is not always fixed or binding as the Alatrofloxacin Price is obtained through a variety of data sources. The Alatrofloxacin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Alatrofloxacin

Synonyms

Alatrofloxacin [inn], 146961-76-4, 7qvv6i50dt, 157182-32-6, Alatrofloxacin (inn), 7-((1r,5s,6s)-6-((s)-2-((s)-2-aminopropanamido)propanamido)-3-azabicyclo[3.1.0]hexan-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid

Cas Number

146961-76-4

Unique Ingredient Identifier (UNII)

7QVV6I50DT

About Alatrofloxacin

Alatrofloxacin is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. It was withdrawn from the U.S. market in 2001.

Alatrofloxacin Manufacturers

A Alatrofloxacin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Alatrofloxacin, including repackagers and relabelers. The FDA regulates Alatrofloxacin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Alatrofloxacin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Alatrofloxacin Suppliers

A Alatrofloxacin supplier is an individual or a company that provides Alatrofloxacin active pharmaceutical ingredient (API) or Alatrofloxacin finished formulations upon request. The Alatrofloxacin suppliers may include Alatrofloxacin API manufacturers, exporters, distributors and traders.

Alatrofloxacin GMP

Alatrofloxacin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Alatrofloxacin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Alatrofloxacin GMP manufacturer or Alatrofloxacin GMP API supplier for your needs.

Alatrofloxacin CoA

A Alatrofloxacin CoA (Certificate of Analysis) is a formal document that attests to Alatrofloxacin's compliance with Alatrofloxacin specifications and serves as a tool for batch-level quality control.

Alatrofloxacin CoA mostly includes findings from lab analyses of a specific batch. For each Alatrofloxacin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Alatrofloxacin may be tested according to a variety of international standards, such as European Pharmacopoeia (Alatrofloxacin EP), Alatrofloxacin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Alatrofloxacin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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