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Chemistry

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Also known as: 13614-98-7, Minocycline hcl, Arestin, Solodyn, Minomycin, Minocin
Molecular Formula
C23H28ClN3O7
Molecular Weight
493.9  g/mol
InChI Key
WTJXVDPDEQKTCV-VQAITOIOSA-N
FDA UNII
0020414E5U

Minocycline Hydrochloride
A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.
1 2D Structure

Minocycline Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4S,4aS,5aR,12aR)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride
2.1.2 InChI
InChI=1S/C23H27N3O7.ClH/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28;/h5-6,9,11,17,27-28,31,33H,7-8H2,1-4H3,(H2,24,32);1H/t9-,11-,17-,23-;/m0./s1
2.1.3 InChI Key
WTJXVDPDEQKTCV-VQAITOIOSA-N
2.1.4 Canonical SMILES
CN(C)C1C2CC3CC4=C(C=CC(=C4C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C.Cl
2.1.5 Isomeric SMILES
CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C.Cl
2.2 Other Identifiers
2.2.1 UNII
0020414E5U
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Akamin

2. Akne Puren

3. Akne-puren

4. Aknemin

5. Aknin Mino

6. Aknin-mino

7. Aknosan

8. Apo Minocycline

9. Apo-minocycline

10. Arestin

11. Blemix

12. Cyclomin

13. Cyclops

14. Dentomycin

15. Dynacin

16. Hydrochloride, Minocycline

17. Icht Oral

18. Icht-oral

19. Klinomycin

20. Lederderm

21. Mestacine

22. Minakne

23. Mino Wolff

24. Mino-wolff

25. Minocin

26. Minocin Mr

27. Minoclir

28. Minocycline

29. Minocycline Monohydrochloride

30. Minocycline, (4r-(4 Alpha,4a Beta,5a Beta,12a Beta))-isomer

31. Minolis

32. Minomycin

33. Minoplus

34. Minotab

35. Minox 50

36. Monohydrochloride, Minocycline

37. Mynocine

2.3.2 Depositor-Supplied Synonyms

1. 13614-98-7

2. Minocycline Hcl

3. Arestin

4. Solodyn

5. Minomycin

6. Minocin

7. Dynacin

8. Periocline

9. Ximino

10. Minocycline (hydrochloride)

11. Vectrin

12. Minomax

13. (4s,4as,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide Hydrochloride

14. Mynocine Hydrochloride

15. Minocycline (as Hydrochloride)

16. Minocycline, Hydrochloride

17. 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride

18. 0020414e5u

19. Tri-mino

20. Nsc-141993

21. Dsstox_cid_24545

22. Dsstox_rid_80306

23. Dsstox_gsid_44545

24. (4s,4as,5ar,12ar)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide;hydrochloride

25. [4s-(4alpha,4aalpha,5aalpha,12aalpha)]-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide Monohydrochloride

26. Lederderm

27. Mynocine

28. Acnez

29. Minomycin Chloride

30. Chebi:50697

31. (4s-(4alpha,4aalpha,5aalpha,12aalpha))-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide Monohydrochloride

32. [4s-(4?,4a?,5a?,12a?)]-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a,tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide

33. 2-naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, Hydrochloride (1:2), (4s,4as,5ar,12as)-

34. Einecs 237-099-7

35. Minocycline Hydrochloride (internal Use)

36. C23h27n3o7.hcl

37. Minocycline, Hcl

38. Unii-0020414e5u

39. Ncgc00096006-01

40. Prestwick_626

41. Arestin (tn)

42. Dynacin (tn)

43. Minocin (tn)

44. Solodyn (tn)

45. Minocycline Hydrochloride [usp:jan]

46. 7-dimethylamino-6-demethyl-6-deoxytetracycline, Hcl

47. Mfcd00083669

48. Minocyclinhydrochlorid

49. Amzeeq

50. Minolira

51. Zilxi

52. Minomycin Hydrochloride

53. Schembl2537

54. Cas-13614-98-7

55. 2-naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, Monohydrochloride, (4s-(4alpha,4aalpha,5aalpha,12aalpha))-

56. Mls002548863

57. Spectrum1500414

58. Fxfm-244

59. Chembl1200881

60. Chembl4576719

61. Dtxsid8044545

62. Hms1568p12

63. Pharmakon1600-01500414

64. Bcp06597

65. Tox21_111250

66. Tox21_113183

67. Tox21_301590

68. Ccg-40107

69. Nsc757120

70. S4226

71. Minocycline Hydrochloride [mi]

72. Minocycline Hydrochloride, Crystalline

73. Akos015951312

74. Minocycline Hydrochloride (jp17/usp)

75. Tox21_111250_1

76. Cs-1256

77. Minocycline Hydrochloride [jan]

78. Nc00460

79. Nsc-757120

80. Minocycline Hydrochloride [mart.]

81. Minocycline Hydrochloride [vandf]

82. Ncgc00178854-03

83. Ncgc00255988-01

84. Ac-22362

85. As-75306

86. Hy-17412

87. Minocycline Hydrochloride [usp-rs]

88. Minocycline Hydrochloride [who-dd]

89. Smr001906766

90. M2288

91. D00850

92. Minocycline Hydrochloride [orange Book]

93. Minocycline Hydrochloride [usp Monograph]

94. 614m987

95. Sr-01000075625

96. Q-201407

97. Sr-01000075625-1

98. Q27104777

99. Minocycline Hydrochloride, Antibiotic For Culture Media Use Only

100. Minocycline Hydrochloride, European Pharmacopoeia (ep) Reference Standard

101. Minocycline Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

102. Minocycline Hydrochloride, United States Pharmacopeia (usp) Reference Standard

103. (4s,12as,4as,5ar)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-4,5,6,12a,4a,5a-hexahydronaphthacene-2-carboxamide Hydrochloride

104. (4s,4as,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamidehydrochloride

105. 2-naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, Monohydrochloride, (4s-(4.alpha.,4a.alpha.,5a.alpha.,12a.alpha.))-

2.4 Create Date
2011-12-26
3 Chemical and Physical Properties
Molecular Weight 493.9 g/mol
Molecular Formula C23H28ClN3O7
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count9
Rotatable Bond Count3
Exact Mass493.1615779 g/mol
Monoisotopic Mass493.1615779 g/mol
Topological Polar Surface Area165 Ų
Heavy Atom Count34
Formal Charge0
Complexity971
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 10  
Drug NameArestin
PubMed HealthMinocycline
Drug ClassesAmebicide, Intestinal, Antiacne, Antiacne Antibacterial, Antibiotic, Antiprotozoal, Tetracycline
Drug LabelARESTIN (minocycline hydrochloride) Microspheres is a subgingival sustained-release product containing the antibiotic minocycline hydrochloride incorporated into a bioresorbable polymer, Poly (glycolide-co-dl-lactide) or PGLA, for professional subg...
Active IngredientMinocycline hydrochloride
Dosage FormPowder, extended release
RouteDental
Strengtheq 1mg base
Market StatusPrescription
CompanyOrapharma

2 of 10  
Drug NameDynacin
Drug LabelMinocycline hydrochloride, is a semisynthetic derivative of tetracycline, 4,7-Bis(dimethylamino)1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1, 11-dioxo-2naphthacenecarboxamide monohydrochloride. Its structural formula is:C23H27N3O7...
Active IngredientMinocycline hydrochloride
Dosage FormCapsule
RouteOral
Strengtheq 100mg base; eq 75mg base
Market StatusPrescription
CompanyCnty Line Pharms

3 of 10  
Drug NameMinocin
PubMed HealthMinocycline, Regular Release (By mouth)
Drug ClassesAmebicide, Intestinal, Antiacne, Antibiotic, Antiprotozoal
Drug LabelMINOCIN minocycline hydrochloride, is a semisynthetic derivative of tetracycline, 4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride.Its structural formula is:C23H27N...
Active IngredientMinocycline hydrochloride
Dosage FormCapsule; Injectable
RouteInjection; Oral
Strengtheq 100mg base; eq 50mg base; eq 100mg base/vial
Market StatusPrescription
CompanyRempex Pharms; Precision Dermat

4 of 10  
Drug NameMinocycline hydrochloride
Drug LabelTo reduce the development of drug-resistant bacteria and maintain the effectiveness of minocycline hydrochloride capsules and other antibacterial drugs, minocycline hydrochloride capsules should be used only to treat or prevent infections that are pr...
Active IngredientMinocycline hydrochloride
Dosage FormTablet, extended release; Tablet; Capsule
Routeoral; Oral
Strength65mg; 115mg; eq 100mg base; eq 50mg base; eq 105mg base; eq 65mg base; eq 115mg base; eq 75mg base; eq 90mg base; eq 80mg base; 55mg; eq 45mg base; eq 55mg base; eq 135mg base
Market StatusTentative Approval; Prescription
CompanyMylan Pharms; Ranbaxy; Teva; Mylan Labs; Sun Pharm Inds; Aurobindo Pharma; Lupin; Barr Labs; Sandoz; Par Pharm; Watson Labs; Ranbaxy Labs; Dr Reddys Labs; Impax Labs

5 of 10  
Drug NameSolodyn
PubMed HealthMinocycline
Drug ClassesAmebicide, Intestinal, Antiacne, Antiacne Antibacterial, Antibiotic, Antiprotozoal, Tetracycline
Drug LabelMinocycline hydrochloride, a semi synthetic derivative of tetracycline, is [4S-(4,4a,5a,12a)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide mono hydrochloride. The structura...
Active IngredientMinocycline hydrochloride
Dosage FormTablet, extended release
RouteOral
Strengtheq 105mg base; eq 65mg base; eq 115mg base; eq 80mg base; eq 55mg base
Market StatusPrescription
CompanyMedicis

6 of 10  
Drug NameArestin
PubMed HealthMinocycline
Drug ClassesAmebicide, Intestinal, Antiacne, Antiacne Antibacterial, Antibiotic, Antiprotozoal, Tetracycline
Drug LabelARESTIN (minocycline hydrochloride) Microspheres is a subgingival sustained-release product containing the antibiotic minocycline hydrochloride incorporated into a bioresorbable polymer, Poly (glycolide-co-dl-lactide) or PGLA, for professional subg...
Active IngredientMinocycline hydrochloride
Dosage FormPowder, extended release
RouteDental
Strengtheq 1mg base
Market StatusPrescription
CompanyOrapharma

7 of 10  
Drug NameDynacin
Drug LabelMinocycline hydrochloride, is a semisynthetic derivative of tetracycline, 4,7-Bis(dimethylamino)1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1, 11-dioxo-2naphthacenecarboxamide monohydrochloride. Its structural formula is:C23H27N3O7...
Active IngredientMinocycline hydrochloride
Dosage FormCapsule
RouteOral
Strengtheq 100mg base; eq 75mg base
Market StatusPrescription
CompanyCnty Line Pharms

8 of 10  
Drug NameMinocin
PubMed HealthMinocycline, Regular Release (By mouth)
Drug ClassesAmebicide, Intestinal, Antiacne, Antibiotic, Antiprotozoal
Drug LabelMINOCIN minocycline hydrochloride, is a semisynthetic derivative of tetracycline, 4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride.Its structural formula is:C23H27N...
Active IngredientMinocycline hydrochloride
Dosage FormCapsule; Injectable
RouteInjection; Oral
Strengtheq 100mg base; eq 50mg base; eq 100mg base/vial
Market StatusPrescription
CompanyRempex Pharms; Precision Dermat

9 of 10  
Drug NameMinocycline hydrochloride
Drug LabelTo reduce the development of drug-resistant bacteria and maintain the effectiveness of minocycline hydrochloride capsules and other antibacterial drugs, minocycline hydrochloride capsules should be used only to treat or prevent infections that are pr...
Active IngredientMinocycline hydrochloride
Dosage FormTablet, extended release; Tablet; Capsule
Routeoral; Oral
Strength65mg; 115mg; eq 100mg base; eq 50mg base; eq 105mg base; eq 65mg base; eq 115mg base; eq 75mg base; eq 90mg base; eq 80mg base; 55mg; eq 45mg base; eq 55mg base; eq 135mg base
Market StatusTentative Approval; Prescription
CompanyMylan Pharms; Ranbaxy; Teva; Mylan Labs; Sun Pharm Inds; Aurobindo Pharma; Lupin; Barr Labs; Sandoz; Par Pharm; Watson Labs; Ranbaxy Labs; Dr Reddys Labs; Impax Labs

10 of 10  
Drug NameSolodyn
PubMed HealthMinocycline
Drug ClassesAmebicide, Intestinal, Antiacne, Antiacne Antibacterial, Antibiotic, Antiprotozoal, Tetracycline
Drug LabelMinocycline hydrochloride, a semi synthetic derivative of tetracycline, is [4S-(4,4a,5a,12a)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide mono hydrochloride. The structura...
Active IngredientMinocycline hydrochloride
Dosage FormTablet, extended release
RouteOral
Strengtheq 105mg base; eq 65mg base; eq 115mg base; eq 80mg base; eq 55mg base
Market StatusPrescription
CompanyMedicis

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Tetracyclines [CS]; Tetracycline-class Drug [EPC]

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IL\/BD-014477 RC\/","address":"FLAT,NO.505, 5TH FLR.,UNIQUE TOWER,","city":"MUMBAI, MAHARASHTRA","supplier":"HONG KONG RONGREYSEN CHEMICAL LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"MELODY HEALTHCARE PRIVATE LIMITED","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"980","totalValueFC":"99281.2","currency":"USD","unitRateINR":"85995","date":"05-Mar-2025","totalValueINR":"8599500","totalValueInUsd":"99281.2","indian_port":"Bombay Air","hs_no":"29413090","bill_no":"8706539","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"UNIT A7 12\/F ASTORIA BUILDING 34 ASHLEY ROAD TSIM SHA TSUI KL, HONG KONG CHINA CHINA","customerAddress":"FLAT,NO.505, 5TH FLR.,UNIQUE TOWER,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1741977000,"product":"MINOCYCLINE HYDROCHLORIDE CHEMICALS","address":"NO.18,DR NAIR ROAD, T NAGAR,","city":"CHENNAI","supplier":"HOVIONE FARMACIENCIA SA","supplierCountry":"PORTUGAL","foreign_port":"LISBON","customer":"STERIL-GENE LIFE SCIENCES PRIVATE LIMITED","customerCountry":"INDIA","quantity":"64.73","actualQuantity":"64.73","unit":"KGS","unitRateFc":"1250","totalValueFC":"82017","currency":"USD","unitRateINR":"109750","date":"15-Mar-2025","totalValueINR":"7104117.5","totalValueInUsd":"82017","indian_port":"Madras Air","hs_no":"29413090","bill_no":"8892432","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"LISBON","supplierAddress":"SETE CASAS 2674-506 LOURES PORTUGAL SDNF PORTUGAL","customerAddress":"NO.18,DR NAIR ROAD, T NAGAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1742236200,"product":"CHEMICAL : MINOCYCLINE HYDROCHLORIDE CHEMICAL : MINOCYCLINE HYDROCHLORIDE","address":"TORRENT HOUSE,","city":"AHMEDABAD. GUJARAT","supplier":"HOVIONE FARMACIENCIA SA","supplierCountry":"PORTUGAL","foreign_port":"LISBON","customer":"TORRENT PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"1400","totalValueFC":"7095.6","currency":"USD","unitRateINR":"122920","date":"18-Mar-2025","totalValueINR":"614600","totalValueInUsd":"7095.6","indian_port":"Ahmedabad Air","hs_no":"29413090","bill_no":"8950964","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"LISBON","supplierAddress":"SATE CASAS 2674-506 LOURES SDNF SDNF PORTUGAL","customerAddress":"TORRENT HOUSE,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1742322600,"product":"MINOCYCLINE HYDROCHLORIDE (CAS NO. 13614-98-7) MINOCYCLINE HYDROCHLORIDE (CAS NO. 13614-98-7)","address":"PLOT NO.2, MAITRIVIHAR,","city":"HYDERABAD\/ANDHRA PRADESH","supplier":"HOVIONE FARMACIENCIA SA","supplierCountry":"PORTUGAL","foreign_port":"LISBON","customer":"AUROBINDO PHARMA LTD","customerCountry":"INDIA","quantity":"350.00","actualQuantity":"350","unit":"KGS","unitRateFc":"1150","totalValueFC":"407994.5","currency":"USD","unitRateINR":"100970","date":"19-Mar-2025","totalValueINR":"35339500","totalValueInUsd":"407994.5","indian_port":"Hyderabad Air","hs_no":"29413090","bill_no":"8970621","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"LISBON","supplierAddress":"SETE CASAS 2674-506 LOURES PORTUGAL SDNF SDNF Portugal","customerAddress":"PLOT NO.2, MAITRIVIHAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1742409000,"product":"MINOCYCLINE HYDROCHLORIDE MINOCYCLINE HYDROCHLORIDE","address":"159, C.S.T. ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"HANGZHOU PROSERRE CHEMICAL CO LTD","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"LUPIN LTD","customerCountry":"INDIA","quantity":"12.15","actualQuantity":"12.15","unit":"KGS","unitRateFc":"1500","totalValueFC":"18473.8","currency":"USD","unitRateINR":"131700","date":"20-Mar-2025","totalValueINR":"1600155","totalValueInUsd":"18473.8","indian_port":"Bombay Air","hs_no":"29413090","bill_no":"8989064","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"ROOM NO 2002 , SUNON CENTRAL MANSIO N NO 200 SHIMIN ROAD , JIANGGAN DIS TRICT , HANGZHOU ZHEJIANG CHINA Han China","customerAddress":"159, C.S.T. ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1742495400,"product":"MINOCYCLINE HYDROCHLORIDE MINOCYCLINE HYDROCHLORIDE","address":"48, KANDIVLI INDUSTRIAL ESTATE,","city":"MUMBAI, MAHARASHTRA.","supplier":"HOVIONE FARMACIENCIA SA","supplierCountry":"PORTUGAL","foreign_port":"LISBON","customer":"IPCA LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"1203","totalValueFC":"121247.8","currency":"USD","unitRateINR":"105021.9","date":"21-Mar-2025","totalValueINR":"10502190","totalValueInUsd":"121247.8","indian_port":"Bombay Air","hs_no":"29413090","bill_no":"9026521","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"LISBON","supplierAddress":"SETE CASAS, 2674-506 LOURES, Portug al SDNF Portugal","customerAddress":"48, KANDIVLI INDUSTRIAL ESTATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1743445800,"product":"MINOCYCLINE HYDROCHLORIDE MICRONIZE","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"HOVIONE FARMACIENCIA SA","supplierCountry":"PORTUGAL","foreign_port":"LISBOA","customer":"DRREDDY'S LABORATORIES LTD","customerCountry":"INDIA","quantity":"240.00","actualQuantity":"240","unit":"KGS","unitRateFc":"2500","totalValueFC":"611903.2","currency":"USD","unitRateINR":"218250","date":"01-Apr-2025","totalValueINR":"52380000","totalValueInUsd":"611903.2","indian_port":"Reddy r-SEZ\/Srikakulam","hs_no":"29419090","bill_no":"9237082","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Micronized","supplierPort":"LISBOA","supplierAddress":"Sete Casas Loures SDNF Portugal","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1743705000,"product":"MINOCYCLINE HYDROCHLORIDE MINOCYCLINE HYDROCHLORIDE","address":"ACME PLAZA, ANDHERI KURLA ROAD,","city":"MUMBAI, MAHARASHTRA.","supplier":"CURIA ITALY SRL-(AKA AMRI ITALY SRL)","supplierCountry":"ITALY","foreign_port":"MILAN","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED","customerCountry":"INDIA","quantity":"60.00","actualQuantity":"60","unit":"KGS","unitRateFc":"1200.4","totalValueFC":"72866.3","currency":"USD","unitRateINR":"103958","date":"04-Apr-2025","totalValueINR":"6237482.08","totalValueInUsd":"72866.3","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"9293872","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN","supplierAddress":"SEDE LEGALE VIA DEL VECCHIO POLITEC ICO,9-20121 MILANO (MI) SDNF IT","customerAddress":"ACME PLAZA, ANDHERI KURLA ROAD,"}]
01-Jan-2022
04-Apr-2025
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DRUG PRODUCT COMPOSITIONS

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DOSAGE - INJECTABLE;INJECTION - EQ 100MG BASE...DOSAGE - INJECTABLE;INJECTION - EQ 100MG BASE/VIAL

USFDA APPLICATION NUMBER - 50444

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DOSAGE - CAPSULE;ORAL - EQ 100MG BASE

USFDA APPLICATION NUMBER - 50649

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DOSAGE - CAPSULE;ORAL - EQ 50MG BASE

USFDA APPLICATION NUMBER - 50649

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DOSAGE - CAPSULE;ORAL - EQ 75MG BASE **Federa...DOSAGE - CAPSULE;ORAL - EQ 75MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 50649

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DOSAGE - POWDER, EXTENDED RELEASE;DENTAL - EQ...DOSAGE - POWDER, EXTENDED RELEASE;DENTAL - EQ 1MG BASE

USFDA APPLICATION NUMBER - 50781

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 1...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 105MG BASE

USFDA APPLICATION NUMBER - 50808

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 1...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 115MG BASE

USFDA APPLICATION NUMBER - 50808

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 1...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 135MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 50808

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 4...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 45MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 50808

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 5...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 55MG BASE

USFDA APPLICATION NUMBER - 50808

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 6...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 65MG BASE

USFDA APPLICATION NUMBER - 50808

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 8...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 80MG BASE

USFDA APPLICATION NUMBER - 50808

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 9...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - EQ 90MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 50808

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01

Brand Name : MINOCYCLINE HYDROCHLORIDE

U.S.A
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Not Confirmed

Brand Name : MINOCYCLINE HYDROCHLORIDE

U.S.A
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Global DDF Summit
Not Confirmed

Minocycline Hydrochloride

Dosage Form : CAPSULE;ORAL

Dosage Strength : EQ 50MG BASE

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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02

Brand Name : MINOCYCLINE HYDROCHLORIDE

U.S.A
arrow
Global DDF Summit
Not Confirmed

Brand Name : MINOCYCLINE HYDROCHLORIDE

U.S.A
arrow
Global DDF Summit
Not Confirmed

Minocycline Hydrochloride

Dosage Form : CAPSULE;ORAL

Dosage Strength : EQ 100MG BASE

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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03

Brand Name : MINOCYCLINE HYDROCHLORIDE

U.S.A
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Global DDF Summit
Not Confirmed

Brand Name : MINOCYCLINE HYDROCHLORIDE

U.S.A
arrow
Global DDF Summit
Not Confirmed

Minocycline Hydrochloride

Dosage Form : CAPSULE;ORAL

Dosage Strength : EQ 75MG BASE

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

blank

04

Brand Name : MINOCYCLINE HYDROCHLORIDE

Ireland
arrow
Global DDF Summit
Not Confirmed

Brand Name : MINOCYCLINE HYDROCHLORIDE

Ireland
arrow
Global DDF Summit
Not Confirmed

Minocycline Hydrochloride

Dosage Form : CAPSULE;ORAL

Dosage Strength : EQ 100MG BASE

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

blank

05

Brand Name : MINOCYCLINE HYDROCHLORIDE

Ireland
arrow
Global DDF Summit
Not Confirmed

Brand Name : MINOCYCLINE HYDROCHLORIDE

Ireland
arrow
Global DDF Summit
Not Confirmed

Minocycline Hydrochloride

Dosage Form : CAPSULE;ORAL

Dosage Strength : EQ 75MG BASE

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

blank

06

Brand Name : MINOCYCLINE HYDROCHLORIDE

Ireland
arrow
Global DDF Summit
Not Confirmed

Brand Name : MINOCYCLINE HYDROCHLORIDE

Ireland
arrow
Global DDF Summit
Not Confirmed

Minocycline Hydrochloride

Dosage Form : CAPSULE;ORAL

Dosage Strength : EQ 50MG BASE

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

blank

07

Brand Name : MINOCYCLINE HYDROCHLORIDE

India
arrow
Global DDF Summit
Not Confirmed

Brand Name : MINOCYCLINE HYDROCHLORIDE

India
arrow
Global DDF Summit
Not Confirmed

Minocycline Hydrochloride

Dosage Form : CAPSULE;ORAL

Dosage Strength : EQ 100MG BASE

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

blank

08

Brand Name : MINOCYCLINE HYDROCHLORIDE

India
arrow
Global DDF Summit
Not Confirmed

Brand Name : MINOCYCLINE HYDROCHLORIDE

India
arrow
Global DDF Summit
Not Confirmed

Minocycline Hydrochloride

Dosage Form : CAPSULE;ORAL

Dosage Strength : EQ 75MG BASE

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

blank

09

Brand Name : MINOCYCLINE HYDROCHLORIDE

India
arrow
Global DDF Summit
Not Confirmed

Brand Name : MINOCYCLINE HYDROCHLORIDE

India
arrow
Global DDF Summit
Not Confirmed

Minocycline Hydrochloride

Dosage Form : CAPSULE;ORAL

Dosage Strength : EQ 50MG BASE

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

blank

10

Brand Name : Minocin

Country
arrow
Global DDF Summit
Not Confirmed

Brand Name : Minocin

Country
arrow
Global DDF Summit
Not Confirmed

Minocycline Hydrochloride

Dosage Form :

Dosage Strength : 16 Cps 50 Mg  

Price Per Pack (Euro) : 6.73

Published in :

Country : Italy

RX/OTC/DISCN : Class C

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ABOUT THIS PAGE

Looking for 13614-98-7 / Minocycline Hydrochloride API manufacturers, exporters & distributors?

Minocycline Hydrochloride manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Minocycline Hydrochloride API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Minocycline Hydrochloride manufacturer or Minocycline Hydrochloride supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Minocycline Hydrochloride manufacturer or Minocycline Hydrochloride supplier.

PharmaCompass also assists you with knowing the Minocycline Hydrochloride API Price utilized in the formulation of products. Minocycline Hydrochloride API Price is not always fixed or binding as the Minocycline Hydrochloride Price is obtained through a variety of data sources. The Minocycline Hydrochloride Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Minocycline Hydrochloride

Synonyms

13614-98-7, Minocycline hcl, Arestin, Solodyn, Minomycin, Minocin

Cas Number

13614-98-7

Unique Ingredient Identifier (UNII)

0020414E5U

About Minocycline Hydrochloride

A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.

Aknosan Manufacturers

A Aknosan manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Aknosan, including repackagers and relabelers. The FDA regulates Aknosan manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Aknosan API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Aknosan manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Aknosan Suppliers

A Aknosan supplier is an individual or a company that provides Aknosan active pharmaceutical ingredient (API) or Aknosan finished formulations upon request. The Aknosan suppliers may include Aknosan API manufacturers, exporters, distributors and traders.

click here to find a list of Aknosan suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Aknosan USDMF

A Aknosan DMF (Drug Master File) is a document detailing the whole manufacturing process of Aknosan active pharmaceutical ingredient (API) in detail. Different forms of Aknosan DMFs exist exist since differing nations have different regulations, such as Aknosan USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Aknosan DMF submitted to regulatory agencies in the US is known as a USDMF. Aknosan USDMF includes data on Aknosan's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Aknosan USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Aknosan suppliers with USDMF on PharmaCompass.

Aknosan JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Aknosan Drug Master File in Japan (Aknosan JDMF) empowers Aknosan API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Aknosan JDMF during the approval evaluation for pharmaceutical products. At the time of Aknosan JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Aknosan suppliers with JDMF on PharmaCompass.

Aknosan KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Aknosan Drug Master File in Korea (Aknosan KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Aknosan. The MFDS reviews the Aknosan KDMF as part of the drug registration process and uses the information provided in the Aknosan KDMF to evaluate the safety and efficacy of the drug.

After submitting a Aknosan KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Aknosan API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Aknosan suppliers with KDMF on PharmaCompass.

Aknosan CEP

A Aknosan CEP of the European Pharmacopoeia monograph is often referred to as a Aknosan Certificate of Suitability (COS). The purpose of a Aknosan CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Aknosan EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Aknosan to their clients by showing that a Aknosan CEP has been issued for it. The manufacturer submits a Aknosan CEP (COS) as part of the market authorization procedure, and it takes on the role of a Aknosan CEP holder for the record. Additionally, the data presented in the Aknosan CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Aknosan DMF.

A Aknosan CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Aknosan CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Aknosan suppliers with CEP (COS) on PharmaCompass.

Aknosan NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Aknosan as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Aknosan API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Aknosan as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Aknosan and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Aknosan NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Aknosan suppliers with NDC on PharmaCompass.

Aknosan GMP

Aknosan Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Aknosan GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Aknosan GMP manufacturer or Aknosan GMP API supplier for your needs.

Aknosan CoA

A Aknosan CoA (Certificate of Analysis) is a formal document that attests to Aknosan's compliance with Aknosan specifications and serves as a tool for batch-level quality control.

Aknosan CoA mostly includes findings from lab analyses of a specific batch. For each Aknosan CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Aknosan may be tested according to a variety of international standards, such as European Pharmacopoeia (Aknosan EP), Aknosan JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Aknosan USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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