Find Afabicin manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

API REF. PRICE (USD/KG)

$
$ 0

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Regulatory FDF Prices

NA

API/FDF Prices: Book a Demo to
explore the features and consider
upgrading later

MARKET PLACE

0

API

0

FDF

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Afabicin [inn], 1518800-35-5, Dmm8663h2r, [6-[(e)-3-[methyl-[(3-methyl-1-benzofuran-2-yl)methyl]amino]-3-oxoprop-1-enyl]-2-oxo-3,4-dihydro-1,8-naphthyridin-1-yl]methyl dihydrogen phosphate, (6-((1e)-3-(methyl((3-methyl-1-benzofuran-2-yl)methyl)amino)-3-oxoprop-1-en-1-yl)-2-oxo-3,4-dihydro-1,8-naphthyridin-1(2h)-yl)methyl dihydrogen phosphate, 2-propenamide, n-methyl-n-((3-methyl-2-benzofuranyl)methyl)-3-(5,6,7,8-tetrahydro-7-oxo-8-((phosphonooxy)methyl)-1,8-naphthyridin-3-yl)-, (2e)-
Molecular Formula
C23H24N3O7P
Molecular Weight
485.4  g/mol
InChI Key
HFYMDQMXVPJNTH-VQHVLOKHSA-N
FDA UNII
DMM8663H2R

Afabicin
Afabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus).
1 2D Structure

Afabicin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[6-[(E)-3-[methyl-[(3-methyl-1-benzofuran-2-yl)methyl]amino]-3-oxoprop-1-enyl]-2-oxo-3,4-dihydro-1,8-naphthyridin-1-yl]methyl dihydrogen phosphate
2.1.2 InChI
InChI=1S/C23H24N3O7P/c1-15-18-5-3-4-6-19(18)33-20(15)13-25(2)21(27)9-7-16-11-17-8-10-22(28)26(23(17)24-12-16)14-32-34(29,30)31/h3-7,9,11-12H,8,10,13-14H2,1-2H3,(H2,29,30,31)/b9-7+
2.1.3 InChI Key
HFYMDQMXVPJNTH-VQHVLOKHSA-N
2.1.4 Canonical SMILES
CC1=C(OC2=CC=CC=C12)CN(C)C(=O)C=CC3=CC4=C(N=C3)N(C(=O)CC4)COP(=O)(O)O
2.1.5 Isomeric SMILES
CC1=C(OC2=CC=CC=C12)CN(C)C(=O)/C=C/C3=CC4=C(N=C3)N(C(=O)CC4)COP(=O)(O)O
2.2 Other Identifiers
2.2.1 UNII
DMM8663H2R
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (6-((1e)-3-(methyl((3-methyl-1-benzofuran-2-yl)methyl)amino)-3-oxo-1-propen-1-yl)-2-oxo-3,4-dihydro-1,8-naphthyridin-1(2h)-yl)methyl Dihydrogen Phosphate

2. 2-propenamide, N-methyl-n-((3-methyl-2-benzofuranyl)methyl)-3-(5,6,7,8-tetrahydro-7-oxo-8-((phosphonooxy)methyl)-1,8-naphthyridin-3-yl)-, (2e)-

3. Afn-1720

4. Debio 1450

5. Debio1450

2.3.2 Depositor-Supplied Synonyms

1. Afabicin [inn]

2. 1518800-35-5

3. Dmm8663h2r

4. [6-[(e)-3-[methyl-[(3-methyl-1-benzofuran-2-yl)methyl]amino]-3-oxoprop-1-enyl]-2-oxo-3,4-dihydro-1,8-naphthyridin-1-yl]methyl Dihydrogen Phosphate

5. (6-((1e)-3-(methyl((3-methyl-1-benzofuran-2-yl)methyl)amino)-3-oxoprop-1-en-1-yl)-2-oxo-3,4-dihydro-1,8-naphthyridin-1(2h)-yl)methyl Dihydrogen Phosphate

6. 2-propenamide, N-methyl-n-((3-methyl-2-benzofuranyl)methyl)-3-(5,6,7,8-tetrahydro-7-oxo-8-((phosphonooxy)methyl)-1,8-naphthyridin-3-yl)-, (2e)-

7. Debio1450

8. Debio 1450

9. Afabicin [who-dd]

10. Unii-dmm8663h2r

11. Chembl4297501

12. Schembl15479062

13. Schembl16262317

14. Gtpl10754

15. Db15268

16. Hy-109000

17. Cs-0030430

18. Q27276486

19. (6-((1e)-3-(methyl((3-methyl-1-benzofuran-2-yl)methyl)amino)-3-oxo-1-propen-1-yl)-2-oxo-3,4-dihydro-1,8-naphthyridin-1(2h)-yl)methyl Dihydrogen Phosphate

2.4 Create Date
2014-01-13
3 Chemical and Physical Properties
Molecular Weight 485.4 g/mol
Molecular Formula C23H24N3O7P
XLogP31
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass485.13518711 g/mol
Monoisotopic Mass485.13518711 g/mol
Topological Polar Surface Area133 Ų
Heavy Atom Count34
Formal Charge0
Complexity833
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


Digital Content read-more

Create Content with PharmaCompass, ask us

NEWS #PharmaBuzz

read-more
read-more

ABOUT THIS PAGE

Looking for 1518800-35-5 / Afabicin API manufacturers, exporters & distributors?

Afabicin manufacturers, exporters & distributors 1

13

PharmaCompass offers a list of Afabicin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Afabicin manufacturer or Afabicin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Afabicin manufacturer or Afabicin supplier.

PharmaCompass also assists you with knowing the Afabicin API Price utilized in the formulation of products. Afabicin API Price is not always fixed or binding as the Afabicin Price is obtained through a variety of data sources. The Afabicin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Afabicin

Synonyms

Afabicin [inn], 1518800-35-5, Dmm8663h2r, [6-[(e)-3-[methyl-[(3-methyl-1-benzofuran-2-yl)methyl]amino]-3-oxoprop-1-enyl]-2-oxo-3,4-dihydro-1,8-naphthyridin-1-yl]methyl dihydrogen phosphate, (6-((1e)-3-(methyl((3-methyl-1-benzofuran-2-yl)methyl)amino)-3-oxoprop-1-en-1-yl)-2-oxo-3,4-dihydro-1,8-naphthyridin-1(2h)-yl)methyl dihydrogen phosphate, 2-propenamide, n-methyl-n-((3-methyl-2-benzofuranyl)methyl)-3-(5,6,7,8-tetrahydro-7-oxo-8-((phosphonooxy)methyl)-1,8-naphthyridin-3-yl)-, (2e)-

Cas Number

1518800-35-5

Unique Ingredient Identifier (UNII)

DMM8663H2R

About Afabicin

Afabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus).

Afabicin Manufacturers

A Afabicin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Afabicin, including repackagers and relabelers. The FDA regulates Afabicin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Afabicin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Afabicin Suppliers

A Afabicin supplier is an individual or a company that provides Afabicin active pharmaceutical ingredient (API) or Afabicin finished formulations upon request. The Afabicin suppliers may include Afabicin API manufacturers, exporters, distributors and traders.

Afabicin GMP

Afabicin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Afabicin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Afabicin GMP manufacturer or Afabicin GMP API supplier for your needs.

Afabicin CoA

A Afabicin CoA (Certificate of Analysis) is a formal document that attests to Afabicin's compliance with Afabicin specifications and serves as a tool for batch-level quality control.

Afabicin CoA mostly includes findings from lab analyses of a specific batch. For each Afabicin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Afabicin may be tested according to a variety of international standards, such as European Pharmacopoeia (Afabicin EP), Afabicin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Afabicin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty