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Also known as: Act-709478, 1838651-58-3, 3z7u1u8z9e, N-(1-((5-cyanopyridin-2-yl)methyl)-1h-pyrazol-3-yl)-2-(4-(1-(trifluoromethyl)cyclopropyl)-phenyl)acetamide, Benzeneacetamide, n-[1-[(5-cyano-2-pyridinyl)methyl]-1h-pyrazol-3-yl]-4-[1-(trifluoromethyl)cyclopropyl]-, N-(1-((5-cyanopyridin-2-yl)methyl)pyrazol-3-yl)-2-(4-(1-(trifluoromethyl)cyclopropyl)phenyl)acetamide
Molecular Formula
C22H18F3N5O
Molecular Weight
425.4  g/mol
InChI Key
LSYANGLAZUZYFX-UHFFFAOYSA-N
FDA UNII
3Z7U1U8Z9E

ACT-709478
ACT-709478 is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients).
1 2D Structure

ACT-709478

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]-2-[4-[1-(trifluoromethyl)cyclopropyl]phenyl]acetamide
2.1.2 InChI
InChI=1S/C22H18F3N5O/c23-22(24,25)21(8-9-21)17-4-1-15(2-5-17)11-20(31)28-19-7-10-30(29-19)14-18-6-3-16(12-26)13-27-18/h1-7,10,13H,8-9,11,14H2,(H,28,29,31)
2.1.3 InChI Key
LSYANGLAZUZYFX-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CC1(C2=CC=C(C=C2)CC(=O)NC3=NN(C=C3)CC4=NC=C(C=C4)C#N)C(F)(F)F
2.2 Other Identifiers
2.2.1 UNII
3Z7U1U8Z9E
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Act-709478

2. N-(1-((5-cyanopyridin-2-yl)methyl)pyrazol-3-yl)-2-(4-(1-(trifluoromethyl)cyclopropyl)phenyl)acetamide

2.3.2 Depositor-Supplied Synonyms

1. Act-709478

2. 1838651-58-3

3. 3z7u1u8z9e

4. N-(1-((5-cyanopyridin-2-yl)methyl)-1h-pyrazol-3-yl)-2-(4-(1-(trifluoromethyl)cyclopropyl)-phenyl)acetamide

5. Benzeneacetamide, N-[1-[(5-cyano-2-pyridinyl)methyl]-1h-pyrazol-3-yl]-4-[1-(trifluoromethyl)cyclopropyl]-

6. N-(1-((5-cyanopyridin-2-yl)methyl)pyrazol-3-yl)-2-(4-(1-(trifluoromethyl)cyclopropyl)phenyl)acetamide

7. N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]-2-[4-[1-(trifluoromethyl)cyclopropyl]phenyl]acetamide

8. Unii-3z7u1u8z9e

9. Chembl4217292

10. Schembl17316866

11. Bcp30302

12. Ex-a3130

13. Bdbm50452245

14. Akos037648975

15. Act 709478

16. Bs-16157

17. Hy-112723

18. Cs-0062884

19. Act709478; Act 709478

20. D80992

2.4 Create Date
2016-02-23
3 Chemical and Physical Properties
Molecular Weight 425.4 g/mol
Molecular Formula C22H18F3N5O
XLogP33.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass425.14634470 g/mol
Monoisotopic Mass425.14634470 g/mol
Topological Polar Surface Area83.6 Ų
Heavy Atom Count31
Formal Charge0
Complexity693
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Calcium Channel Blockers

A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)


ABOUT THIS PAGE

Looking for 1838651-58-3 / ACT-709478 API manufacturers, exporters & distributors?

ACT-709478 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of ACT-709478 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right ACT-709478 manufacturer or ACT-709478 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred ACT-709478 manufacturer or ACT-709478 supplier.

PharmaCompass also assists you with knowing the ACT-709478 API Price utilized in the formulation of products. ACT-709478 API Price is not always fixed or binding as the ACT-709478 Price is obtained through a variety of data sources. The ACT-709478 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

ACT-709478

Synonyms

1838651-58-3, 3z7u1u8z9e, N-(1-((5-cyanopyridin-2-yl)methyl)-1h-pyrazol-3-yl)-2-(4-(1-(trifluoromethyl)cyclopropyl)-phenyl)acetamide, Benzeneacetamide, n-[1-[(5-cyano-2-pyridinyl)methyl]-1h-pyrazol-3-yl]-4-[1-(trifluoromethyl)cyclopropyl]-, N-(1-((5-cyanopyridin-2-yl)methyl)pyrazol-3-yl)-2-(4-(1-(trifluoromethyl)cyclopropyl)phenyl)acetamide, N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]-2-[4-[1-(trifluoromethyl)cyclopropyl]phenyl]acetamide

Cas Number

1838651-58-3

Unique Ingredient Identifier (UNII)

3Z7U1U8Z9E

About ACT-709478

ACT-709478 is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients).

ACT 709478 Manufacturers

A ACT 709478 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of ACT 709478, including repackagers and relabelers. The FDA regulates ACT 709478 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. ACT 709478 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

ACT 709478 Suppliers

A ACT 709478 supplier is an individual or a company that provides ACT 709478 active pharmaceutical ingredient (API) or ACT 709478 finished formulations upon request. The ACT 709478 suppliers may include ACT 709478 API manufacturers, exporters, distributors and traders.

ACT 709478 GMP

ACT 709478 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of ACT 709478 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right ACT 709478 GMP manufacturer or ACT 709478 GMP API supplier for your needs.

ACT 709478 CoA

A ACT 709478 CoA (Certificate of Analysis) is a formal document that attests to ACT 709478's compliance with ACT 709478 specifications and serves as a tool for batch-level quality control.

ACT 709478 CoA mostly includes findings from lab analyses of a specific batch. For each ACT 709478 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

ACT 709478 may be tested according to a variety of international standards, such as European Pharmacopoeia (ACT 709478 EP), ACT 709478 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (ACT 709478 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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