Find Acriflavine manufacturers, exporters & distributors on PharmaCompass

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Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 8048-52-0, Acriflavin, Acriflavine neutral, Flavacridine, Triphaflavine, 65589-70-0
Molecular Formula
C27H25ClN6
Molecular Weight
469.0  g/mol
InChI Key
PEJLNXHANOHNSU-UHFFFAOYSA-N

Acriflavine
3,6-Diamino-10-methylacridinium chloride mixt. with 3,6-acridinediamine. Fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.
1 2D Structure

Acriflavine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
acridine-3,6-diamine;10-methylacridin-10-ium-3,6-diamine;chloride
2.1.2 InChI
InChI=1S/C14H13N3.C13H11N3.ClH/c1-17-13-7-11(15)4-2-9(13)6-10-3-5-12(16)8-14(10)17;14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;/h2-8H,1H3,(H3,15,16);1-7H,14-15H2;1H
2.1.3 InChI Key
PEJLNXHANOHNSU-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C[N+]1=C2C=C(C=CC2=CC3=C1C=C(C=C3)N)N.C1=CC(=CC2=NC3=C(C=CC(=C3)N)C=C21)N.[Cl-]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 2,8-diamino-10-methylacridinium Chloride Mixture With 2,8-diaminoacridine

2. Xanthacridinum

2.2.2 Depositor-Supplied Synonyms

1. 8048-52-0

2. Acriflavin

3. Acriflavine Neutral

4. Flavacridine

5. Triphaflavine

6. 65589-70-0

7. Acridine-3,6-diamine;10-methylacridin-10-ium-3,6-diamine;chloride

8. Dsstox_cid_25848

9. Dsstox_rid_81170

10. Dsstox_gsid_45848

11. Acriflavine [nf]

12. Flavacridinum

13. 3,6-diamino-10-methylacridinium Chloride-3,6-acridinediamine Mixt

14. Fungus Cure

15. Cas-69235-50-3

16. Mfcd00064307

17. Neutroflavin

18. Ccris 5428

19. Unii-1t3a50395t

20. Acriflavini Chloridium

21. Flavacridine Hydrochloirde

22. Acriflavine, Hydrochloride

23. Acriflavine Dihydrochloride

24. Schembl77745

25. Acriflavinium Chloride [inn]

26. Unii-1s73vw819c

27. Acriflavine Hydrochloride [nf]

28. Chembl2360628

29. Dtxsid30988185

30. 1s73vw819c

31. Amy22363

32. Rkl10102

33. Tox21_111337

34. 3,6-diamino-10-methylacridin-10-ium Acridine-3,6-diamine Chloride

35. Akos015902524

36. Tox21_111337_1

37. 1t3a50395t

38. Cs-6959

39. Nsc 757387

40. Ncgc00178831-03

41. Hy-100575

42. A0134

43. D88218

44. 3,6-diamino-10-methylacridiniumchloride-3,6-acridinediaminemixt

45. 3,6-diamino-10-methylacridinium Chloride Mixt. With 3,6-diaminoacridine

46. 3,6-diamino-10-methylacridin-10-ium Chloride--acridine-3,6-diamine (1/1/1)

47. Acriflavine (mixture Of 3,6-diamino-10-methylacridinium Chloride And 3,6-diaminoacridine)

48. 68518-47-8

2.3 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 469.0 g/mol
Molecular Formula C27H25ClN6
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count0
Exact Mass468.1829225 g/mol
Monoisotopic Mass468.1829225 g/mol
Topological Polar Surface Area121 Ų
Heavy Atom Count34
Formal Charge0
Complexity486
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Intercalating Agents

Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA. (See all compounds classified as Intercalating Agents.)


Anti-Infective Agents, Local

Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects. (See all compounds classified as Anti-Infective Agents, Local.)


Fluorescent Dyes

Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags. (See all compounds classified as Fluorescent Dyes.)


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ABOUT THIS PAGE

Looking for 8048-52-0 / Acriflavine API manufacturers, exporters & distributors?

Acriflavine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Acriflavine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Acriflavine manufacturer or Acriflavine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Acriflavine manufacturer or Acriflavine supplier.

PharmaCompass also assists you with knowing the Acriflavine API Price utilized in the formulation of products. Acriflavine API Price is not always fixed or binding as the Acriflavine Price is obtained through a variety of data sources. The Acriflavine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Acriflavine

Synonyms

8048-52-0, Acriflavin, Acriflavine neutral, Flavacridine, Triphaflavine, 65589-70-0

Cas Number

8048-52-0

About Acriflavine

3,6-Diamino-10-methylacridinium chloride mixt. with 3,6-acridinediamine. Fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.

Acriflavine Manufacturers

A Acriflavine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Acriflavine, including repackagers and relabelers. The FDA regulates Acriflavine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Acriflavine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Acriflavine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Acriflavine Suppliers

A Acriflavine supplier is an individual or a company that provides Acriflavine active pharmaceutical ingredient (API) or Acriflavine finished formulations upon request. The Acriflavine suppliers may include Acriflavine API manufacturers, exporters, distributors and traders.

click here to find a list of Acriflavine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Acriflavine GMP

Acriflavine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Acriflavine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Acriflavine GMP manufacturer or Acriflavine GMP API supplier for your needs.

Acriflavine CoA

A Acriflavine CoA (Certificate of Analysis) is a formal document that attests to Acriflavine's compliance with Acriflavine specifications and serves as a tool for batch-level quality control.

Acriflavine CoA mostly includes findings from lab analyses of a specific batch. For each Acriflavine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Acriflavine may be tested according to a variety of international standards, such as European Pharmacopoeia (Acriflavine EP), Acriflavine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Acriflavine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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