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    Chemistry

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    Also known as:
    Molecular Formula
    C19H19N7O6
    Molecular Weight
    441.4  g/mol
    InChI Key
    OVBPIULPVIDEAO-LBPRGKRZSA-N
    Folic Acid
    1 2D Structure

    Folic Acid

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
    2.1.2 InChI
    InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
    2.1.3 InChI Key
    OVBPIULPVIDEAO-LBPRGKRZSA-N
    2.1.4 Canonical SMILES
    C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)N=C(N3)N
    2.1.5 Isomeric SMILES
    C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)N=C(N3)N
    2.2 Create Date
    2004-09-16
    3 Chemical and Physical Properties
    Molecular Weight 441.4 g/mol
    Molecular Formula C19H19N7O6
    XLogP3-1.1
    Hydrogen Bond Donor Count6
    Hydrogen Bond Acceptor Count9
    Rotatable Bond Count9
    Exact Mass441.13968135 g/mol
    Monoisotopic Mass441.13968135 g/mol
    Topological Polar Surface Area209 Ų
    Heavy Atom Count32
    Formal Charge0
    Complexity767
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameFolic acid
    PubMed HealthFolic Acid
    Drug ClassesNutriceutical, Nutritive Agent
    Drug LabelFolic acid, N-[p-[[(2-amino-4-hydroxy-6-pteridiny)methyl]amino]benzoyl]-L-glutamic acid, is a B complex vitamin containing a pteridine moiety linked by a methylene bridge to para-aminobenzoic acid, which is joined by a peptide linkage to glutamic aci...
    Active IngredientFolic acid
    Dosage FormTablet; Injectable
    RouteInjection; Oral
    Strength1 mg; 1mg; 5mg/ml
    Market StatusPrescription
    CompanyBicon Pharm; Excellium; Jubilant Cadista; Cadila Pharms; Invagen Pharms; Hikma Pharms; Watson Labs; Amneal Pharm; Fresenius Kabi Usa; Vintage; Contract Pharmacal

    2 of 2  
    Drug NameFolic acid
    PubMed HealthFolic Acid
    Drug ClassesNutriceutical, Nutritive Agent
    Drug LabelFolic acid, N-[p-[[(2-amino-4-hydroxy-6-pteridiny)methyl]amino]benzoyl]-L-glutamic acid, is a B complex vitamin containing a pteridine moiety linked by a methylene bridge to para-aminobenzoic acid, which is joined by a peptide linkage to glutamic aci...
    Active IngredientFolic acid
    Dosage FormTablet; Injectable
    RouteInjection; Oral
    Strength1 mg; 1mg; 5mg/ml
    Market StatusPrescription
    CompanyBicon Pharm; Excellium; Jubilant Cadista; Cadila Pharms; Invagen Pharms; Hikma Pharms; Watson Labs; Amneal Pharm; Fresenius Kabi Usa; Vintage; Contract Pharmacal

    API Reference Price

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ACID NOT FOR MEDICINAL USE","address":"25 BUNDER STREET","city":"CHENNAI","supplier":"JIANGXI TIANXIN PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"PANVO ORGANICS PRIVATE LTD","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"65.1","totalValueFC":"33002.1","currency":"USD","unitRateINR":"5623.6","date":"16-May-2025","totalValueINR":"2811804.07","totalValueInUsd":"33002.1","indian_port":"Madras Air","hs_no":"29362910","bill_no":"2100380","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"LEPING INDUSTRIAL ZONE LEPING JIAN GXI 333300 CHINA, , CHINA SDNF CHINA","customerAddress":"25 BUNDER STREET"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1751481000,"product":"CHROMIUM PICOLINATE (CHROMIUM 12%) - USA FOLIC ACID PH - (FOR MEDICINAL USE)SWITZERLAND","address":"401 4TH FL WINDSOR HOUSE CST RD","city":"MUMBAI, MAHARASHTRA.","supplier":"DSM NUTRITIONAL PRODUCTS ASIA PACIFIC","supplierCountry":"UNITED STATES","foreign_port":"WARSAW","customer":"DSM NUTRITIONAL PRODUCTS INDIA PRIVATE LTD","customerCountry":"INDIA","quantity":"4.00","actualQuantity":"4","unit":"KGS","unitRateFc":"4266","totalValueFC":"17377.9","currency":"INR","unitRateINR":"373910.8","date":"03-Jul-2025","totalValueINR":"1495643","totalValueInUsd":"17377.9","indian_port":"Bombay Air","hs_no":"29362990","bill_no":"3022966","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"WARSAW","supplierAddress":"30 PASIR PANJANG ROAD #13-31, MAPLE TREE BUSINESS CITY, Singapore - 117 440, , Singapore Singapore","customerAddress":"401 4TH FL WINDSOR HOUSE CST RD"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1755455400,"product":"FOLIC ACID (NOT FOR MEDICINAL USE) NA","address":"25D, Basant Vihar,","city":"Agra","supplier":"AMS CHINA HK COLIMITED CO","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"RADHASHOK PHARMACHEM PRIVATE LTD","customerCountry":"INDIA","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"32.5","totalValueFC":"32901.2","currency":"USD","unitRateINR":"2879.5","date":"18-Aug-2025","totalValueINR":"2879500","totalValueInUsd":"32901.2","indian_port":"Delhi Air","hs_no":"29309099","bill_no":"3939910","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"UNIT 1406A,14\/F,THE BELGIAN BANK BUILDING,NOS.721 -725 NATHAN ROAD KOWLOON,HONGKONG, CHINA","customerAddress":"25D, Basant Vihar,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1758911400,"product":"FOLIC ACID USP23 (NOT FOR MEDICINAL USE) FOLIC ACID USP23 (NOT FOR MEDICINAL USE)","address":"AGARWAL B2B CENTRE, 604 KANCHPADA","city":"MUMBAI","supplier":"JIANGSU HERU CHEMICAL TRADING CO.,LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SUN RISE ENTERPRISES","customerCountry":"INDIA","quantity":"1500.00","actualQuantity":"1500","unit":"KGS","unitRateFc":"32","totalValueFC":"48363.2","currency":"USD","unitRateINR":"2846","date":"27-Sep-2025","totalValueINR":"4268974","totalValueInUsd":"48363.2","indian_port":"JNPT","hs_no":"29362910","bill_no":"4762819","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ROOM 1308, NO.12, MINZHI ROAD, YUHUATAI DISTRICT,NANJING, JIANGSU JIANGSU PROVINCE,CHINA CN","customerAddress":"AGARWAL B2B CENTRE, 604 KANCHPADA"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1759775400,"product":"FOLIC ACID PH - SWITZERLAND (FOR MEDICINAL USE) FOLIC ACID PH - (FOR MEDICINAL USE)SWITZERLAND","address":"401 4TH FL WINDSOR HOUSE CST RD","city":"MUMBAI, MAHARASHTRA.","supplier":"DSM NUTRITIONAL PRODUCTS ASIA PACIFIC","supplierCountry":"SWITZERLAND","foreign_port":"ROTTERDAM","customer":"DSM NUTRITIONAL PRODUCTS INDIA PRIVATE LTD","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"137","totalValueFC":"278056.8","currency":"N\/A","unitRateINR":"12286","date":"07-Oct-2025","totalValueINR":"24572000","totalValueInUsd":"278056.8","indian_port":"JNPT","hs_no":"29362910","bill_no":"4944966","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"ROTTERDAM","supplierAddress":"30 PASIR PANJANG ROAD #13-31, MAPLE TREE BUSINESS CITY, Singapore - 117 440, , Singapore Singapore","customerAddress":"401 4TH FL WINDSOR HOUSE CST RD"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1760466600,"product":"QUATREFOLIC (6S)-5 METHYLTETRAHYDROFOLIC ACID, GLUCOSAMINE SALT(BATCH NO:CM25001068)QUATREFOLIC (6S)-5 METHYLTETRAHYDROFOLIC ACID, GLUCOSAMINE S","address":"OLD NO.24 NEW NO.5,1ST MAIN ROAD,","city":"CHENNAI , TAMIL NADU.","supplier":"GENCOR PACIFIC LTD","supplierCountry":"ITALY","foreign_port":"MILAN","customer":"GENCOR PACIFIC ORGANICS INDIA PRIVATE LTD","customerCountry":"INDIA","quantity":"5.20","actualQuantity":"5.2","unit":"KGS","unitRateFc":"8319.8","totalValueFC":"43913.9","currency":"N\/A","unitRateINR":"746286.1","date":"15-Oct-2025","totalValueINR":"3880687.51","totalValueInUsd":"43913.9","indian_port":"Madras Air","hs_no":"29362990","bill_no":"5117092","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN","supplierAddress":"301 KAM ON BUILDING 176-A,QUEENS RO AD CENTRAL, HONG KONG SDNF HONG KONG","customerAddress":"OLD NO.24 NEW NO.5,1ST MAIN ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1760639400,"product":"FOLIC ACID 96% FEED GRADE - (NOT FOR HUMAN\/MEDICINAL USE,FORUSE IN ANIMAL FEED ONLY)FOLIC ACID 96% FEED GRADE","address":"IS.40 KHB INDUSTRIAL AREA","city":"BANGALORE ,KARNATAKA","supplier":"CARGILL INTERNATIONAL S A","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"PROVIMI ANIMAL NUTRITION INDIA PRIVATE LTD","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"45.4","totalValueFC":"13661.6","currency":"USD","unitRateINR":"4024.3","date":"17-Oct-2025","totalValueINR":"1207281.69","totalValueInUsd":"13661.6","indian_port":"Madras Sea","hs_no":"29362910","bill_no":"5154754","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ESPLANADE DE PONT-ROUGE 4 , CH-1212 GRAND-LANCY GENEVE CH","customerAddress":"IS.40 KHB INDUSTRIAL AREA"}]
    16-Jan-2022
    28-Nov-2025
    KGS
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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - FOR SOLUTION;INTRAVENOUS - 80MG/VIAL...DOSAGE - FOR SOLUTION;INTRAVENOUS - 80MG/VIAL;0.02MG/VIAL;0.001MG/VIAL;5MG/VIAL;0.01MG/VIAL;0.14MG/VIAL;17MG/VIAL;0.2MG/VIAL;1MG/VIAL;1.4MG/VIAL;EQ 1.2MG BASE/VIAL;0.7MG/VIAL;7MG/VIAL

    USFDA APPLICATION NUMBER - 18920

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    DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/...DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;0.03MG/ML

    USFDA APPLICATION NUMBER - 21163

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    DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/...DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;30MCG/ML

    USFDA APPLICATION NUMBER - 21163

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    DOSAGE - INJECTABLE;INTRAVENOUS - 200MG/VIAL;...DOSAGE - INJECTABLE;INTRAVENOUS - 200MG/VIAL;0.06MG/VIAL;0.005MG/VIAL;15MG/VIAL;0.005MG/VIAL;0.6MG/VIAL;40MG/VIAL;6MG/VIAL;3.6MG/VIAL;6MG/VIAL;1MG/VIAL;10MG/VIAL;0.15MG/VIAL

    USFDA APPLICATION NUMBER - 21625

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    DOSAGE - INJECTABLE;INJECTION - 20MG/ML;0.006...DOSAGE - INJECTABLE;INJECTION - 20MG/ML;0.006MG/ML;0.05MCG/ML;1.5MG/ML;0.0005MG/ML;0.06MG/ML;4MG/ML;0.6MG/ML;0.36MG/ML;0.6MG/ML;0.1MG/ML;1MG/ML

    USFDA APPLICATION NUMBER - 8809

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    ABOUT THIS PAGE

    Looking for / Folic Acid API manufacturers, exporters & distributors?

    Folic Acid manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Folic Acid API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Folic Acid manufacturer or Folic Acid supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Folic Acid manufacturer or Folic Acid supplier.

    PharmaCompass also assists you with knowing the Folic Acid API Price utilized in the formulation of products. Folic Acid API Price is not always fixed or binding as the Folic Acid Price is obtained through a variety of data sources. The Folic Acid Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Folic Acid

    Acide folique Manufacturers

    A Acide folique manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Acide folique, including repackagers and relabelers. The FDA regulates Acide folique manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Acide folique API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Acide folique manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Acide folique Suppliers

    A Acide folique supplier is an individual or a company that provides Acide folique active pharmaceutical ingredient (API) or Acide folique finished formulations upon request. The Acide folique suppliers may include Acide folique API manufacturers, exporters, distributors and traders.

    click here to find a list of Acide folique suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Acide folique USDMF

    A Acide folique DMF (Drug Master File) is a document detailing the whole manufacturing process of Acide folique active pharmaceutical ingredient (API) in detail. Different forms of Acide folique DMFs exist exist since differing nations have different regulations, such as Acide folique USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Acide folique DMF submitted to regulatory agencies in the US is known as a USDMF. Acide folique USDMF includes data on Acide folique's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Acide folique USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Acide folique suppliers with USDMF on PharmaCompass.

    Acide folique JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Acide folique Drug Master File in Japan (Acide folique JDMF) empowers Acide folique API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Acide folique JDMF during the approval evaluation for pharmaceutical products. At the time of Acide folique JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Acide folique suppliers with JDMF on PharmaCompass.

    Acide folique CEP

    A Acide folique CEP of the European Pharmacopoeia monograph is often referred to as a Acide folique Certificate of Suitability (COS). The purpose of a Acide folique CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Acide folique EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Acide folique to their clients by showing that a Acide folique CEP has been issued for it. The manufacturer submits a Acide folique CEP (COS) as part of the market authorization procedure, and it takes on the role of a Acide folique CEP holder for the record. Additionally, the data presented in the Acide folique CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Acide folique DMF.

    A Acide folique CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Acide folique CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Acide folique suppliers with CEP (COS) on PharmaCompass.

    Acide folique WC

    A Acide folique written confirmation (Acide folique WC) is an official document issued by a regulatory agency to a Acide folique manufacturer, verifying that the manufacturing facility of a Acide folique active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Acide folique APIs or Acide folique finished pharmaceutical products to another nation, regulatory agencies frequently require a Acide folique WC (written confirmation) as part of the regulatory process.

    click here to find a list of Acide folique suppliers with Written Confirmation (WC) on PharmaCompass.

    Acide folique NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Acide folique as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Acide folique API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Acide folique as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Acide folique and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Acide folique NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Acide folique suppliers with NDC on PharmaCompass.

    Acide folique GMP

    Acide folique Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Acide folique GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Acide folique GMP manufacturer or Acide folique GMP API supplier for your needs.

    Acide folique CoA

    A Acide folique CoA (Certificate of Analysis) is a formal document that attests to Acide folique's compliance with Acide folique specifications and serves as a tool for batch-level quality control.

    Acide folique CoA mostly includes findings from lab analyses of a specific batch. For each Acide folique CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Acide folique may be tested according to a variety of international standards, such as European Pharmacopoeia (Acide folique EP), Acide folique JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Acide folique USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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