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Also known as: 1188-21-2, Acetyl-l-leucine, Ac-leu-oh, N-acetylleucine, L-acetylleucine, (s)-2-acetamido-4-methylpentanoic acid
Molecular Formula
C8H15NO3
Molecular Weight
173.21  g/mol
InChI Key
WXNXCEHXYPACJF-ZETCQYMHSA-N
FDA UNII
E915HL7K2O

N-Acetyl-L-Leucine
N-acetyl-leu is a natural product found in Mus musculus, Euglena gracilis, and other organisms with data available.
1 2D Structure

N-Acetyl-L-Leucine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-acetamido-4-methylpentanoic acid
2.1.2 InChI
InChI=1S/C8H15NO3/c1-5(2)4-7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/t7-/m0/s1
2.1.3 InChI Key
WXNXCEHXYPACJF-ZETCQYMHSA-N
2.1.4 Canonical SMILES
CC(C)CC(C(=O)O)NC(=O)C
2.1.5 Isomeric SMILES
CC(C)C[C@@H](C(=O)O)NC(=O)C
2.2 Other Identifiers
2.2.1 UNII
E915HL7K2O
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Acetyl-dl-leucine

2. Acetylleucine

3. Acetylleucine, L-

4. Lasdol

5. N-acetylleucine

6. Tanganil

2.3.2 Depositor-Supplied Synonyms

1. 1188-21-2

2. Acetyl-l-leucine

3. Ac-leu-oh

4. N-acetylleucine

5. L-acetylleucine

6. (s)-2-acetamido-4-methylpentanoic Acid

7. N-acetyl-leucine

8. Leucine, N-acetyl-, L-

9. (2s)-2-acetamido-4-methylpentanoic Acid

10. Leucine, N-acetyl-

11. (s)-2-acetylamino-4-methyl-pentanoic Acid

12. N-acetyl-l-leucin

13. L-leucine, N-acetyl-

14. Nsc 206316

15. E915hl7k2o

16. (2s)-2-(acetylamino)-4-methylpentanoic Acid

17. Chebi:17786

18. Cas-1188-21-2

19. Mfcd00065131

20. Dsstox_cid_25870

21. Dsstox_rid_81188

22. Dsstox_gsid_45870

23. N-acetyl-leu

24. Unii-e915hl7k2o

25. Acetyl-leucine

26. N-acetyl Leucine

27. Nsc-206316

28. Ncgc00094935-01

29. Einecs 214-706-3

30. Nall

31. N-acetyl-(l)-leucine

32. Spectrum_001313

33. (2s)-2-acetamido-4-methyl-pentanoic Acid

34. Maybridge1_002565

35. Prestwick0_000896

36. Prestwick1_000896

37. Prestwick2_000896

38. Prestwick3_000896

39. Spectrum2_000475

40. Spectrum3_001480

41. Spectrum4_000036

42. Spectrum5_001242

43. Acetylleucine, L-

44. Acetylleucine, (s)-

45. Bspbio_000712

46. Bspbio_003039

47. Kbiogr_000471

48. Kbioss_001793

49. Chembl56021

50. Divk1c_000622

51. Divk1c_001317

52. Schembl282372

53. Spectrum1502001

54. Spbio_000610

55. Spbio_002921

56. Bpbio1_000784

57. Dtxsid6045870

58. Hms501p04

59. Hms548m13

60. Kbio1_000622

61. Kbio2_001793

62. Kbio2_004361

63. Kbio2_006929

64. Kbio3_002539

65. N-acetyl-l-(-)-leucine

66. Ninds_000622

67. Hms1570d14

68. Hms1921b16

69. Hms2097d14

70. Hms3714d14

71. Pharmakon1600-01502001

72. Zinc135384

73. Act06842

74. Tox21_111362

75. Ccg-40254

76. N-acetyl-l-leucine [usp-rs]

77. Nsc758152

78. S3109

79. Akos000302149

80. Akos010400978

81. Tox21_111362_1

82. Fd20066

83. Cds1_000277

84. Idi1_000622

85. Ncgc00016567-01

86. Ncgc00016567-02

87. Ncgc00016567-03

88. Ncgc00016567-05

89. Ac-22375

90. Hy-59291

91. Ms-20482

92. Sbi-0051693.p002

93. N-acetyl-l-leucine, Reagentplus(r), 99%

94. A0098

95. Ab00513952

96. Am20080126

97. Bb 0256992

98. Cs-0007651

99. A-1460

100. A16391

101. C02710

102. M03063

103. Ab00052251_03

104. 188a212

105. N-acetyl-l-leucine, Vetec(tm) Reagent Grade, 98%

106. Brd-k27406233-001-05-1

107. Q63395724

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 173.21 g/mol
Molecular Formula C8H15NO3
XLogP30.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass173.10519334 g/mol
Monoisotopic Mass173.10519334 g/mol
Topological Polar Surface Area66.4 Ų
Heavy Atom Count12
Formal Charge0
Complexity177
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API Reference Price

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22-Feb-2022
23-Aug-2024
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API | Excipient name

N-Acetyl-L-Leucine

Synonyms

1188-21-2, Acetyl-l-leucine, Ac-leu-oh, N-acetylleucine, L-acetylleucine, (s)-2-acetamido-4-methylpentanoic acid

Cas Number

1188-21-2

Unique Ingredient Identifier (UNII)

E915HL7K2O

About N-Acetyl-L-Leucine

N-acetyl-leu is a natural product found in Mus musculus, Euglena gracilis, and other organisms with data available.

ACETYLLEUCINE, (S)- Manufacturers

A ACETYLLEUCINE, (S)- manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of ACETYLLEUCINE, (S)-, including repackagers and relabelers. The FDA regulates ACETYLLEUCINE, (S)- manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. ACETYLLEUCINE, (S)- API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of ACETYLLEUCINE, (S)- manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

ACETYLLEUCINE, (S)- Suppliers

A ACETYLLEUCINE, (S)- supplier is an individual or a company that provides ACETYLLEUCINE, (S)- active pharmaceutical ingredient (API) or ACETYLLEUCINE, (S)- finished formulations upon request. The ACETYLLEUCINE, (S)- suppliers may include ACETYLLEUCINE, (S)- API manufacturers, exporters, distributors and traders.

click here to find a list of ACETYLLEUCINE, (S)- suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

ACETYLLEUCINE, (S)- GMP

ACETYLLEUCINE, (S)- Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of ACETYLLEUCINE, (S)- GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right ACETYLLEUCINE, (S)- GMP manufacturer or ACETYLLEUCINE, (S)- GMP API supplier for your needs.

ACETYLLEUCINE, (S)- CoA

A ACETYLLEUCINE, (S)- CoA (Certificate of Analysis) is a formal document that attests to ACETYLLEUCINE, (S)-'s compliance with ACETYLLEUCINE, (S)- specifications and serves as a tool for batch-level quality control.

ACETYLLEUCINE, (S)- CoA mostly includes findings from lab analyses of a specific batch. For each ACETYLLEUCINE, (S)- CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

ACETYLLEUCINE, (S)- may be tested according to a variety of international standards, such as European Pharmacopoeia (ACETYLLEUCINE, (S)- EP), ACETYLLEUCINE, (S)- JP (Japanese Pharmacopeia) and the US Pharmacopoeia (ACETYLLEUCINE, (S)- USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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