Synopsis
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USDMF
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CEP/COS
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JDMF
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EU WC
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KDMF
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NDC API
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VMF
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EDQM
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USP
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JP
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Others
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FDF Dossiers
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FDA Orange Book
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Europe
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Canada
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Australia
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South Africa
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Listed Dossiers
DRUG PRODUCT COMPOSITIONS
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US Patents
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US Exclusivities
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Health Canada Patents
1. 98-86-2
2. 1-phenylethanone
3. Methyl Phenyl Ketone
4. Acetylbenzene
5. Phenyl Methyl Ketone
6. Ethanone, 1-phenyl-
7. Hypnone
8. Benzoyl Methide
9. Acetophenon
10. 1-phenylethan-1-one
11. Acetylbenzol
12. 1-phenyl-1-ethanone
13. Benzoylmethide
14. Benzene, Acetyl-
15. Phenylethanone
16. Acetofenon
17. Ketone, Methyl Phenyl
18. 1-phenyl-ethanone
19. Usaf Ek-496
20. Acetofenon [czech]
21. Rcra Waste Number U004
22. Hypnon
23. Methylphenylketone
24. Phenylmethylketone
25. Nsc 7635
26. Fema No. 2009
27. Dymex
28. Rcra Waste No. U004
29. Ai3-00575
30. Ketone, Methyl Phenyl-
31. Chembl274467
32. Rk493whv10
33. Chebi:27632
34. Nsc-7635
35. Dsstox_cid_1828
36. Dsstox_rid_76353
37. Dsstox_gsid_21828
38. Fema Number 2009
39. Cas-98-86-2
40. Ac0
41. (2,2,2,-2h3)acetophenone
42. Ccris 1341
43. Hsdb 969
44. Einecs 202-708-7
45. Unii-rk493whv10
46. Aceto Phenone
47. Aceto-phenone
48. Acetyl-benzen
49. Acetyl-benzene
50. Alpha-acetophenone
51. Ethanone,1-phenyl
52. Methyl-phenyl Ketone
53. Methyl Phenyl-ketone
54. Nchem.180-comp5
55. Acetophenone-[13c6]
56. 1-phenylethanone, 9ci
57. Acetophenone [ii]
58. Acetophenone [mi]
59. Schembl737
60. Acetophenone [fcc]
61. Bmse000286
62. Acetophenone [fhfi]
63. Acetophenone [hsdb]
64. Acetophenone [inci]
65. Ec 202-708-7
66. Wln: 1vr
67. Acetophenone, >=98%, Fg
68. Schembl8170205
69. 1-phenylethanone (acetophenone)
70. Dtxsid6021828
71. Schembl13341485
72. Acetophenone, Analytical Standard
73. Fema 2009
74. Nsc7635
75. Acetophenone, >=98.0% (gc)
76. Acetophenone, Natural, 98%, Fg
77. Zinc896628
78. Hy-y0989
79. Str00017
80. Tox21_202422
81. Tox21_300343
82. Acetophenone, Reagentplus(r), 99%
83. Bdbm50236986
84. C0117
85. Mfcd00008724
86. S5528
87. Akos000119011
88. Ccg-266074
89. Db04619
90. Ncgc00248000-01
91. Ncgc00248000-02
92. Ncgc00254370-01
93. Ncgc00259971-01
94. Acetophenone 100 Microg/ml In Cyclohexane
95. Db-044220
96. A0061
97. Cs-0015982
98. Ft-0628908
99. Ft-0636694
100. Ft-0637564
101. Ft-0641367
102. Ft-0661057
103. Acetophenone, Puriss. P.a., >=99.0% (gc)
104. C07113
105. D71016
106. A854783
107. Q375112
108. J-519533
109. Z57127548
110. Acetophenone, Tracecert(r), Certified Reference Material
| Molecular Weight | 120.15 g/mol |
|---|---|
| Molecular Formula | C8H8O |
| XLogP3 | 1.6 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 1 |
| Exact Mass | 120.057514874 g/mol |
| Monoisotopic Mass | 120.057514874 g/mol |
| Topological Polar Surface Area | 17.1 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 101 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Photosensitizing Agents
Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active metabolite to produce a beneficial reaction affecting the diseased tissue. These compounds can be administered topically or systemically and have been used therapeutically to treat psoriasis and various types of neoplasms. (See all compounds classified as Photosensitizing Agents.)
... In rats acetophenone appears to be precursor of not only mandelic acid and benzoylformic acid but benzoic acid as well. ...
PMID:1274370 Sullivan HR et al; Xenobiotica 6 (1): 49-54 (1976)
The reductive cleavage of hydroperoxides by purified p450 in a reconstituted system containing reduced nicotinamide adenine dinucleotide phosphate was studied. ... With cumyl hydroperoxide, acetophenone was produced, but not cumyl alcohol, indicating that a rearrangement had taken place, probably involving radical intermediates, with the formation of an additional 1-carbon product.
Vaz ADN, Coon MJ; Proceedings of the Nat Acad of Sci 84 (5): 1172-6 (1987)
Early studies identified 1-phenylethanol, benzoic acid, and mandelic acid as urinary metabolites of acetophenone in rabbits and dogs. /It was/ found that rabbits administered acetophenone by gavage excreted 47% of the dose as glucuronide conjugates of 1-phenylethanol and about 20% as hippuric acid. /Another study/... reported that 1-phenylethanol and its glucuronide conjugate constituted only about 4% of the dose for rabbits treated by the ip route. ... m-Hydroxyacetophenone, p-hydroxyacetophenone, and w-hydroxyacetophenone as minor urinary metabolites of acetophenone (<1% of the dose) in rabbits.
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V6 297
...10% of a 100 mg/kg ip dose of radiolabeled acetophenone was excreted as /carbon dioxide/ after 4 hr and that the amount increased to 30% after 13 hr. ... Mendelic acid was present in the urine of rats treated ip with acetophenone and ... this metabolite most likely arose from w-hydroxyacetophenone.
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V6 297
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ANALYTICAL
Analytical Methods
ABOUT THIS PAGE
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PharmaCompass offers a list of Acetophenone API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Acetophenone manufacturer or Acetophenone supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Acetophenone manufacturer or Acetophenone supplier.
PharmaCompass also assists you with knowing the Acetophenone API Price utilized in the formulation of products. Acetophenone API Price is not always fixed or binding as the Acetophenone Price is obtained through a variety of data sources. The Acetophenone Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Acetophenone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Acetophenone, including repackagers and relabelers. The FDA regulates Acetophenone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Acetophenone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Acetophenone manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Acetophenone supplier is an individual or a company that provides Acetophenone active pharmaceutical ingredient (API) or Acetophenone finished formulations upon request. The Acetophenone suppliers may include Acetophenone API manufacturers, exporters, distributors and traders.
click here to find a list of Acetophenone suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
Acetophenone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Acetophenone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Acetophenone GMP manufacturer or Acetophenone GMP API supplier for your needs.
A Acetophenone CoA (Certificate of Analysis) is a formal document that attests to Acetophenone's compliance with Acetophenone specifications and serves as a tool for batch-level quality control.
Acetophenone CoA mostly includes findings from lab analyses of a specific batch. For each Acetophenone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Acetophenone may be tested according to a variety of international standards, such as European Pharmacopoeia (Acetophenone EP), Acetophenone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Acetophenone USP).
