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Find Drugs in Development News & Deals for 62-33-9

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Details:

Mino-Lok (MLT) is a novel antibiotic lock therapy that combines minocycline with edetate disodium, which is investigated for the treatment of patients with catheter-related blood stream infections.


Lead Product(s): Minocycline Hydrochloride,Edetate Calcium Disodium,Ethanol

Therapeutic Area: Infections and Infectious Diseases Product Name: Mino-Lok

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 02, 2024

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revyve™ Antimicrobial Wound Gel is indicated for management of ulcers (including diabetic foot and leg ulcers and pressure ulcers), 1st and 2nd degree burns, partial & full thickness wounds, large surface area wounds and surgical incisions for adult populations.


Lead Product(s): Edetate Calcium Disodium,Citric Acid

Therapeutic Area: Podiatry Product Name: Revye

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 02, 2023

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Elores, a cutting-edge antibiotic novel combination of Ceftriaxone (third generation beta-lactam cephalosporin), Sulbactam (beta-lactamase inhibitor) and Disodium EDTA (Class 1 Antibiotic Resistance Breaker) for complicated urinary tract infections.


Lead Product(s): Ceftriaxone,Edetate Calcium Disodium,Sulbactam

Therapeutic Area: Infections and Infectious Diseases Product Name: Elores

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 14, 2023

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Mino-Lok (MLT), a novel antibiotic lock therapy that combines minocycline with edetate disodium, which is investigated for the treatment of patients with catheter-related blood stream infections.


Lead Product(s): Minocycline Hydrochloride,Edetate Calcium Disodium,Ethanol

Therapeutic Area: Infections and Infectious Diseases Product Name: Mino-Lok

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: The University of Texas MD Anderson Cancer Center

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 10, 2023

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  • Development Update

Details:

Edetate calcium disodium for injection is a prescription medicine, used for the reduction of blood levels and depot stores of lead in lead poisoning (acute and chronic) and lead encephalopathy, in both pediatric populations and adults.


Lead Product(s): Edetate Calcium Disodium

Therapeutic Area: Pharmacology/Toxicology Product Name: Edetate Calcium Disodium-Generic

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 10, 2023

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The net proceeds will be used to fund the company's pre-clinical and clinical development of its product candidates, including Mino-Lok® (minocycline), an antibiotic lock solution used to treat patients with catheter-related bloodstream infections (CRBSIs) and CLABSIs.


Lead Product(s): Minocycline Hydrochloride,Edetate Calcium Disodium,Ethanol

Therapeutic Area: Infections and Infectious Diseases Product Name: Mino-Lok

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: H.C. Wainwright & Co.

Deal Size: $15.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering May 08, 2023

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Under the agreement, ProgenaCare will commercialize coactiv+ (disodium EDTA) Antimicrobial Wound Gel in the U.S. wound care market. The coactiv+ is a combination of Kane’s patented coactiv+™ technology and PHMB, paired with a non-ionic pluronic surfactant.


Lead Product(s): Edetate Calcium Disodium,Sodium Citrate

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: Coactiv+

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Kane Biotech

Deal Size: Undisclosed Upfront Cash: $0.5 million

Deal Type: Agreement April 20, 2023

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The coactiv+™ (disodium EDTA) Antimicrobial Hydrogel is a combination of Kane’s patented coactiv+™ antibiofilm technology and PHMB in a thermo-reversible gel.


Lead Product(s): Edetate Calcium Disodium,Sodium Citrate

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: Coactiv+

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Salud Pharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement January 04, 2023

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  • Deals

Details:

AB569 has been shown to kill multi-drug resistant (MDR) Gram-negative (G-) bacteria such as Pseudomonasaeruginosa, that is responsible for over half of all severe burn infections, and identified as a “major pathogen” by the Centers for Disease Control and Prevention.


Lead Product(s): Acidified nitrite,Edetate Calcium Disodium

Therapeutic Area: Infections and Infectious Diseases Product Name: AB569

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Arch Biopartners

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement March 24, 2021

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Paper published in the journal PloS One demonstrated that AB569 kills multi-drug resistant strains of Acinetobacter baumannii and Acinetobacter spp. bacteria.


Lead Product(s): Acidified nitrite,Edetate Calcium Disodium

Therapeutic Area: Infections and Infectious Diseases Product Name: AB569

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 04, 2021

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The paper demonstrates key data on the synergistic effects of acidified sodium nitrite and EDTA (active ingredients of AB569) on destroying all bacteria


Lead Product(s): Sodium Nitrite,Edetate Calcium Disodium

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 21, 2020

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