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1. 2,4-dimethylphenol Potassium
2. 2,4-dimethylphenol Sodium
3. 2,4-dimethylphenol Titanium (+4)
4. 2,4-dmp
5. 2,4-xylenol
1. 105-67-9
2. 2,4-xylenol
3. M-xylenol
4. Phenol, 2,4-dimethyl-
5. 4,6-dimethylphenol
6. 1-hydroxy-2,4-dimethylbenzene
7. 4-hydroxy-1,3-dimethylbenzene
8. Rcra Waste Number U101
9. 2,4-dimethyl Phenol
10. Nsc 3829
11. 2,4-dimethyl-phenol
12. Chebi:34241
13. Nsc-3829
14. Mfcd00002233
15. 5od803c081
16. Dsstox_cid_1864
17. Dsstox_rid_76371
18. Dsstox_gsid_21864
19. Caswell No. 907a
20. Lysol Brand Disinfectant
21. Cas-105-67-9
22. Bulk Lysol Brand Disinfectant
23. Ccris 721
24. Hsdb 4253
25. 2,4-dmp
26. Gable-tite Dark Creosote (creola)
27. Benzene, 2,4-dimethyl-1-hydroxy-
28. Du Cor Concentrated Fly Insecticide
29. Gable-tite Light Creosote (creola)
30. Einecs 203-321-6
31. Rcra Waste No. U101
32. Epa Pesticide Chemical Code 086804
33. Brn 0636244
34. Ai3-17612
35. Unii-5od803c081
36. 2,4dimethylphenol
37. 2.4-dimethylphenol
38. 4-hydroxy-m-xylene
39. Ec 203-321-6
40. Schembl92167
41. 2,4-dimethylphenol, 98%
42. 4-06-00-03126 (beilstein Handbook Reference)
43. Mls002152861
44. Bidd:er0275
45. Chembl29878
46. Wln: Qr B1 D1
47. Dimethylphenol, 2,4-
48. 1,3-dimethyl-4-hydroxybenzene
49. 2,4-xylenol, >=98%
50. Dtxsid2021864
51. Nsc3829
52. 2,4-dimethylphenol 2,4-xylenol
53. Hms3039j10
54. Xylenol 2,4-dimethylphenol
55. 2,4-dimethylphenol [hsdb]
56. Act00460
57. Zinc1672873
58. Tox21_201787
59. Tox21_300051
60. Bbl011443
61. Stl146554
62. Akos000121556
63. Am62796
64. 2,4-dimethylphenol, Analytical Standard
65. Ncgc00091611-01
66. Ncgc00091611-02
67. Ncgc00091611-03
68. Ncgc00091611-04
69. Ncgc00091611-05
70. Ncgc00253938-01
71. Ncgc00259336-01
72. Xylenol 2,4-dimethylphenol [mi]
73. Ps-11923
74. Smr001224485
75. Db-010714
76. Metacresol Impurity F [ep Impurity]
77. D0774
78. Ft-0610239
79. 2,4-dimethylphenol 100 Microg/ml In Methanol
80. Q2437536
81. W-108780
82. 2,4-dimethylphenol, Pestanal(r), Analytical Standard
83. F0001-0111
84. N0d
| Molecular Weight | 122.16 g/mol |
|---|---|
| Molecular Formula | C8H10O |
| XLogP3 | 2.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 122.073164938 g/mol |
| Monoisotopic Mass | 122.073164938 g/mol |
| Topological Polar Surface Area | 20.2 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 90.6 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
SUBJECTS WERE EXPOSED TO M-XYLENE AT CONCN OF ABOUT 3.9 MMOL/CU M FOR 5 DAYS, 6 HR/DAY. RATE OF 2,4-XYLENOL EXCRETION SHORTLY AFTER EXPOSURE WAS ABOUT 1-2% OF THAT FOR METHYLHIPPURIC ACID EXCRETION AND PULMONARY EXCRETION OF UNCHANGED XYLENE WAS ABOUT 4% OF UPTAKE.
RIIHIMAKI V ET AL; SCAND J WORK ENVIRON HEALTH 5 (3): 217-31 (1979)
The concn of 2,4-dimethylphenol was determined /in/ several tissues of the rat after 6 hr constant iv infusion and after iv bolus injection. 2,4-dimethylphenol was distributed rapidly in the brain and liver, /and had/ high tissue-plasma concn ratios for the brain, liver, and fat. Accumulation of 2,4-dimethylphenol in these tissues was negligible.
PMID:7067652 Kata JS et al; Ecotoxicol Environ Saf 6 (1): 35-40 (1982)
FOLLOWING IV ADMIN OF 17 MG/KG OF THE 2,4-ISOMER TO RATS, THE BRAIN ACCUMULATED THE HIGHEST AMT ON A PER G BASIS, FOLLOWED BY FAT AND LIVER. RATIOS OF BRAIN, LIVER AND FAT TO PLASMA /CONCN/ WERE APPROX 1, 1.5 AND 2, RESPECTIVELY.
SOMANI SM; FED PROC FED AM SOC EXP BIOL 40 (3PT1): 698 (1981)
2,4-DIMETHYLPHENOL DISTRIBUTED RAPIDLY THROUGH THE BODY AFTER IV BOLUS ADMIN OF 30 MG/KG. PLASMA, LIVER AND FAT CONCN DISAPPEARED PRIOR TO 60 MIN BUT PERSISTED IN THE BRAIN.
SOMANI SM; FED PROC FED AM SOC EXP BIOL 40 (3PT1): 698 (1981)
Associations between o-cresol, p-cresol, m-cresol, 2,4-xylenol, 2,5-xylenol, 3,4-xylenol, and 3,5-xylenol exposure levels and urinary phenol excretion were examined in the coke facility industry. The subjects consisted of 76 exposed workers employed in the tar distillation process and 34 controls. ... Urinary metabolite levels were corrected for specific gravity and creatinine. The time weighted average exposure concentrations in the breathing zones of the tar distillation workers were ... 0.02 to 0.04 mg/cu m for xylenols. ... The urinary xylenol levels of exposed workers ranged from 0.12 to 0.97 mg/l with specific gravity correction. In control urine samples, the specific gravity corrected xylenol concentrations ranged from 25 x 10(-3) to 43 x 10(-3) mg/l. Significant correlations were observed between the ambient levels and urinary concentrations of phenol, o-cresol, and the xylenols, with coefficients ranging from 0.45 to 0.82. The author concludes that the biological monitoring of urinary xylenols may be used as a means of measuring xylenol exposure in coke facility workers.
PMID:9352337 Bieniek G; International Archives of Occupational and Environmental Health 70 (5): 334-40 (1997)
METABOLISM OF 2,4-DIMETHYLPHENOL IN ANIMALS IS VERY SIMILAR TO THAT OF CRESOLS ... .
National Research Council. Drinking Water & Health Volume 1. Washington, DC: National Academy Press, 1977., p. 730
Rats were admin 2,4-dimethylphenol for 6 hr constantly by iv infusion or iv bolus injection. 2,4-Dimethylphenol was rapidly metabolized to its conjugates (94.3%) within 30 min; the glucuronide constituted 53% and other conjugates 41% /in plasma/.
PMID:7067652 Kata JS et al; Ecotoxicol Environ Saf 6 (1): 35-40 (1982)
IN WORKERS SIMULTANEOUSLY EXPOSED TO ETHYLBENZENES AND XYLENES, 2,4-DIMETHYLPHENOL, A METABOLITE OF M-XYLENE, COULD NOT BE DETECTED.
PMID:437902 ANGERER J, LEHNERT G; INT ARCH OCCUP ENVIRON HEALTH 43 (2): 145-50 (1979)
HYDROXYLATION OF AROMATIC HYDROCARBONS WAS STUDIED FOLLOWING THEIR ORAL ADMINISTRATION TO RATS THAT ALSO RECEIVED A PURIFIED DIET CONTAINING NEOMYCIN TO REDUCE THE LEVELS OF NORMALLY OCCURRING SIMPLE URINARY PHENOLS. PHENOLIC METABOLITES WERE QUANTITATIVELY ESTIMATED IN HYDROLYZED URINE SAMPLES BY GAS CHROMATOGRAPHY. M-XYLENE ADMINISTERED AT A DOSE OF 100 MG/KG WAS METABOLIZED TO 2,4-DIMETHYLPHENOL TO THE EXTENT OF 0.9% OF THE DOSE GIVEN.
PMID:5422210 BAKKE OM, SCHELINE RR; TOXICOL APPL PHARMACOL 16 (3): 691-700 (1970)
For more Metabolism/Metabolites (Complete) data for 2,4-DIMETHYLPHENOL (6 total), please visit the HSDB record page.
2,4-Dimethylphenol is a known human metabolite of m-xylene.
S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560
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