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11116-46-4
Also known as: 2971-90-6, 3,5-dichloro-2,6-dimethylpyridin-4-ol, Meticlorpindol, Coyden, Lerbek, Coccidiostat c
Molecular Formula
C7H7Cl2NO
Molecular Weight
192.04  g/mol
InChI Key
ZDPIZLCVJAAHHR-UHFFFAOYSA-N
FDA UNII
8J763HFF5N

A very effective anticoccidial agent used in poultry.
1 2D Structure

11116-46-4

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3,5-dichloro-2,6-dimethyl-1H-pyridin-4-one
2.1.2 InChI
InChI=1S/C7H7Cl2NO/c1-3-5(8)7(11)6(9)4(2)10-3/h1-2H3,(H,10,11)
2.1.3 InChI Key
ZDPIZLCVJAAHHR-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C(C(=O)C(=C(N1)C)Cl)Cl
2.2 Other Identifiers
2.2.1 UNII
8J763HFF5N
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3,5-dichloro-2,6-dimethyl-4-pyridinol

2. Clopindol

3. Meticlorpindol

2.3.2 Depositor-Supplied Synonyms

1. 2971-90-6

2. 3,5-dichloro-2,6-dimethylpyridin-4-ol

3. Meticlorpindol

4. Coyden

5. Lerbek

6. Coccidiostat C

7. Metichlorpindol

8. Methylchlorpindol

9. Methylchloropindol

10. 4-pyridinol, 3,5-dichloro-2,6-dimethyl-

11. Clopindol

12. Coyden 25

13. 3,5-dichloro-2,6-dimethyl-4-pyridinol

14. Rigekokcin (rigecoccin)

15. 3,5-dichloro-2,6-dimethyl-1h-pyridin-4-one

16. 2,6-dimethyl-3,5-dichloro-4-pyridinol

17. Nsc 253479

18. 3,5-dichloro-4-hydroxy-2,6-dimethylpyridine

19. Brn 1527826

20. Nsc-253479

21. 8j763hff5n

22. 3,5-dichloro-2,6-dimethylpyridin-4(1h)-one

23. Ncgc00095166-01

24. 3,5-dichloro-2,6-dimethyl-4-hydroxypyridine

25. Clopidol 100 Microg/ml In Acetonitrile/methanol

26. Dsstox_cid_21793

27. Dsstox_rid_79844

28. Dsstox_gsid_41793

29. Clopidolo [dcit]

30. Clopidolum

31. Farmcoccid

32. Pharmcoccid

33. Pharmcoccide

34. Clopidolo

35. Caswell No. 306aa

36. Clopidolum [inn-latin]

37. Clopidol [usan:inn:ban]

38. Cas-2971-90-6

39. Einecs 221-008-2

40. Epa Pesticide Chemical Code 306200

41. Unii-8j763hff5n

42. Hsdb 7907

43. 3,6-dimethylpyridine

44. Clopidol [usan]

45. Clopidol (usan/inn)

46. Clopidol [inn]

47. Clopidol [mi]

48. Spectrum2_000018

49. Spectrum3_001952

50. Clopidol [mart.]

51. 3,6-dimethyl-4-pyridinol

52. Bspbio_003552

53. Clopidol [green Book]

54. Schembl661598

55. Spectrum1505319

56. Spbio_000055

57. Chembl446918

58. Dtxsid8041793

59. Schembl11480048

60. Kbio3_002866

61. Chebi:183853

62. Hms1922d10

63. Hms2090o19

64. Hms2093b15

65. Pharmakon1600-01505319

66. Hy-b1088

67. Zinc8830661

68. Tox21_111465

69. 3,5-dichloro-2,6-dimethylpyridinol

70. Bbl011029

71. Ccg-40048

72. Clopidol 100 Microg/ml In Methanol

73. Mfcd00867211

74. Nsc253479

75. Nsc758964

76. S4142

77. Stk802181

78. Stl032651

79. Akos005622703

80. Akos005642292

81. Tox21_111465_1

82. Cs-4655

83. Ks-1254

84. Nsc-758964

85. 4-pyridinol,5-dichloro-2,6-dimethyl-

86. Clopidol 100 Microg/ml In Acetonitrile

87. Ncgc00095166-02

88. Ncgc00095166-03

89. Ncgc00095166-04

90. Ac-24199

91. Wr-61112

92. 3,5-dichloro-2,6-dimethyl-pyridin-4-ol

93. Sbi-0206752.p001

94. Db-047634

95. Ft-0603199

96. Clopidol, Vetranal(tm), Analytical Standard

97. A16464

98. D03559

99. Ab01563058_01

100. 971c906

101. 971d906

102. A820023

103. Sr-05000002003

104. J-017612

105. Q5135111

106. Sr-05000002003-1

107. Brd-k80036624-001-03-2

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 192.04 g/mol
Molecular Formula C7H7Cl2NO
XLogP32.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass190.9904692 g/mol
Monoisotopic Mass190.9904692 g/mol
Topological Polar Surface Area29.1 Ų
Heavy Atom Count11
Formal Charge0
Complexity252
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Therapeutic Uses

THERAPEUTIC CATEGORY (VETERINARY): Coccidiostat

O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 403


Used as an anticoccidiostat in poultry.

American Conference of Governmental Industrial Hygienists. Documentation of the TLV's and BEI's with Other World Wide Occupational Exposure Values. CD-ROM Cincinnati, OH 45240-4148 2010.


Clopidol is mainly coccidiostatic and is active only against the sporozoite stage of Eimeria.

Sams R; Ullmann's Encyclopedia of Industrial Chemistry 7th ed. (2010). NY, NY: John Wiley & Sons; Veterinary Drugs. Online Posting Date: June 15, 2000


MEDICATION (VET): Turkeys grown for meat purposes only: As an aid in the prevention of leucocytozoonosis caused by Leucocytozoon smithi.

US Natl Inst Health; DailyMed. Current Medication Information for COYDEN (clopidol) powder (March 2010). Available from, as of March 8, 2011: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=16475&CFID=55487510&CFTOKEN=245e1f8f4d81dce0-5FF4B3EE-CC3A-992F-5E755E9D27611217&jsessionid=ca3047782f012955657f


MEDICATION (VET): Broiler and replacement chickens: As an aid in the prevention of coccidiosis in broilers and replacements for caged layers caused by E. tenella, Eimeria necatrix, Eimeria Acervulina, Eimeria maxima, Eimeria brunetti, Eimeria mivati.

US Natl Inst Health; DailyMed. Current Medication Information for COYDEN (clopidol) powder (March 2010). Available from, as of March 8, 2011: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=16475&CFID=55487510&CFTOKEN=245e1f8f4d81dce0-5FF4B3EE-CC3A-992F-5E755E9D27611217&jsessionid=ca3047782f012955657f


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Coccidiostats

Agents useful in the treatment or prevention of COCCIDIOSIS in man or animals. (See all compounds classified as Coccidiostats.)


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