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1,2-Propanediol carbonate
Also known as: 108-32-7, 4-methyl-1,3-dioxolan-2-one, 1,2-propylene carbonate, 1,2-propanediol cyclic carbonate, Cyclic propylene carbonate, Texacar pc
Molecular Formula
C4H6O3
Molecular Weight
102.09  g/mol
InChI Key
RUOJZAUFBMNUDX-UHFFFAOYSA-N
FDA UNII
8D08K3S51E

1 2D Structure

1,2-Propanediol carbonate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-methyl-1,3-dioxolan-2-one
2.1.2 InChI
InChI=1S/C4H6O3/c1-3-2-6-4(5)7-3/h3H,2H2,1H3
2.1.3 InChI Key
RUOJZAUFBMNUDX-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1COC(=O)O1
2.2 Other Identifiers
2.2.1 UNII
8D08K3S51E
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Cyclic Propylene Carbonate

2.3.2 Depositor-Supplied Synonyms

1. 108-32-7

2. 4-methyl-1,3-dioxolan-2-one

3. 1,2-propylene Carbonate

4. 1,2-propanediol Cyclic Carbonate

5. Cyclic Propylene Carbonate

6. Texacar Pc

7. 1,3-dioxolan-2-one, 4-methyl-

8. Arconate 5000

9. 1,2-propanediol Carbonate

10. 1-methylethylene Carbonate

11. Cyclic 1,2-propylene Carbonate

12. Dipropylene Carbonate

13. 1,2-propanediyl Carbonate

14. 4-methyldioxalone-2

15. Propylene Glycol Cyclic Carbonate

16. Cyclic Methylethylene Carbonate

17. 4-methyl-2-oxo-1,3-dioxolane

18. Carbonic Acid, Propylene Ester

19. Carbonic Acid, Cyclic Propylene Ester

20. Nsc 11784

21. Propylenester Kyseliny Uhlicite

22. Carbonic Acid Cyclic Methylethylene Ester

23. Propylenecarbonate, 99%

24. Nsc-11784

25. Propylene Carbonate [nf]

26. 8d08k3s51e

27. Propylene Carbonate (nf)

28. Wln: T5ovotj D

29. Dsstox_cid_6789

30. 1,3-dioxolan-2-one, 4-methyl-, Homopolymer

31. Dsstox_rid_78214

32. Dsstox_gsid_26789

33. 110320-40-6

34. Cas-108-32-7

35. Hsdb 6806

36. Pc-hp

37. Einecs 203-572-1

38. Carbonic Acid, Cyclic Propylene Ether

39. 4-methyl-1,3-dioxolane-2-one

40. Propylenester Kyseliny Uhlicite [czech]

41. Brn 0107913

42. Butylhexanoate

43. Unii-8d08k3s51e

44. Ai3-19724

45. Mfcd00798264

46. Mfcd00798265

47. Solvenon Pc

48. Propylen Carbonate

49. Mfcd00005385

50. Carbonic Acid Propylene

51. Arconate Propylene Carbonate

52. Ec 203-572-1

53. Schembl15309

54. 5-19-04-00021 (beilstein Handbook Reference)

55. 1-propanediol Cyclic Carbonate

56. (s)-1,2-propanediol Carbonate

57. Chembl1733973

58. Dtxsid2026789

59. Propylene Carbonate [ii]

60. 2-oxo-4-methyl-1,3-dioxolane

61. 1,2-pdc

62. 4-methyl-[1,3]dioxolan-2-one

63. Nsc1913

64. Propylene Carbonate [hsdb]

65. Propylene Carbonate [inci]

66. Propylene Carbonate [vandf]

67. Nsc-1913

68. Nsc11784

69. Propylene Carbonate (battery Grade)

70. Propylene Carbonate [mart.]

71. Tox21_202047

72. Tox21_303214

73. Bbl027518

74. Propylene Carbonate [usp-rs]

75. Stl373011

76. Akos009158417

77. Propylene Carbonate (industrial Grade)

78. Sb66353

79. Propylene Carbonate, Anhydrous, 99.7%

80. Ncgc00165974-01

81. Ncgc00165974-02

82. Ncgc00256995-01

83. Ncgc00259596-01

84. Propylene Carbonate, For Hplc, 99.7%

85. Bp-30108

86. Bp-31155

87. Sy008770

88. Sy066861

89. Db-018081

90. Propylene Carbonate, Reagentplus(r), 99%

91. Cs-0076373

92. Ft-0602265

93. Ft-0639979

94. Ft-0660009

95. Ft-0674103

96. P0525

97. D05633

98. Propylene Carbonate, Anhydrous, Water 50ppm Max.

99. Propylene Carbonate, Selectophore(tm), >=99.0%

100. Q415979

101. J-002116

102. Propylene Carbonate, Vetec(tm) Reagent Grade, 98%

103. F0001-0165

104. Propylene Carbonate, >=99%, Acid <10 Ppm, H2o <10 Ppm

105. 1,2-propanediol Cyclic Carbonate, 4-methyl-1,3-dioxolan-2-one

106. Propylene Carbonate, United States Pharmacopeia (usp) Reference Standard

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 102.09 g/mol
Molecular Formula C4H6O3
XLogP3-0.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass102.031694049 g/mol
Monoisotopic Mass102.031694049 g/mol
Topological Polar Surface Area35.5 Ų
Heavy Atom Count7
Formal Charge0
Complexity88.9
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Absorption, Distribution and Excretion

A dermal absorption study using living skin from human donors indicated that propylene carbonate had permeability constants of /average (standard deviation)/ 0.7 (0.4) g/sq m/hr and 0.6 (0.3) cu cm/sq m/hr.

Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V6 940


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