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    Chemistry

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    Also known as: Tranylcypromine sulfate, 13492-01-8, Tranylcypromine sulfate (usp), Chebi:9653, D00826
    Molecular Formula
    C18H24N2O4S
    Molecular Weight
    364.5  g/mol
    InChI Key
    BKPRVQDIOGQWTG-VYIKEJMZSA-N
    Tranylcypromine Sulfate
    A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)
    1 2D Structure

    Tranylcypromine Sulfate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (1R)-2-phenylcyclopropan-1-amine;sulfuric acid
    2.1.2 InChI
    InChI=1S/2C9H11N.H2O4S/c2*10-9-6-8(9)7-4-2-1-3-5-7;1-5(2,3)4/h2*1-5,8-9H,6,10H2;(H2,1,2,3,4)/t2*8?,9-;/m11./s1
    2.1.3 InChI Key
    BKPRVQDIOGQWTG-VYIKEJMZSA-N
    2.1.4 Canonical SMILES
    C1C(C1N)C2=CC=CC=C2.C1C(C1N)C2=CC=CC=C2.OS(=O)(=O)O
    2.1.5 Isomeric SMILES
    C1[C@H](C1C2=CC=CC=C2)N.C1[C@H](C1C2=CC=CC=C2)N.OS(=O)(=O)O
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Jatrosom

    2. Parnate

    3. Sulfate, Tranylcypromine

    4. Trans 2 Phenylcyclopropylamine

    5. Trans-2-phenylcyclopropylamine

    6. Transamine

    7. Tranylcypromine

    8. Tranylcypromine Sulfate

    2.2.2 Depositor-Supplied Synonyms

    1. Tranylcypromine Sulfate

    2. 13492-01-8

    3. Tranylcypromine Sulfate (usp)

    4. Chebi:9653

    5. D00826

    2.3 Create Date
    2008-02-08
    3 Chemical and Physical Properties
    Molecular Weight 364.5 g/mol
    Molecular Formula C18H24N2O4S
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count2
    Exact Mass364.14567842 g/mol
    Monoisotopic Mass364.14567842 g/mol
    Topological Polar Surface Area135 Ų
    Heavy Atom Count25
    Formal Charge0
    Complexity197
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count2
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Anxiety Agents

    Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)

    Antidepressive Agents

    Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)

    Monoamine Oxidase Inhibitors

    A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414) (See all compounds classified as Monoamine Oxidase Inhibitors.)

    4.2 FDA Pharmacological Classification
    4.2.1 Pharmacological Classes
    Monoamine Oxidase Inhibitors [MoA]; Monoamine Oxidase Inhibitor [EPC]

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    ABOUT THIS PAGE

    Looking for 13492-01-8 / Tranylcypromine Sulfate API manufacturers, exporters & distributors?

    Tranylcypromine Sulfate manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Tranylcypromine Sulfate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Tranylcypromine Sulfate manufacturer or Tranylcypromine Sulfate supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Tranylcypromine Sulfate manufacturer or Tranylcypromine Sulfate supplier.

    API | Excipient name

    Tranylcypromine Sulfate

    Synonyms

    13492-01-8, Tranylcypromine sulfate (usp), Chebi:9653, D00826

    Cas Number

    13492-01-8

    About Tranylcypromine Sulfate

    A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)

    Tranylcypromine Sulfate Manufacturers

    A Tranylcypromine Sulfate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tranylcypromine Sulfate, including repackagers and relabelers. The FDA regulates Tranylcypromine Sulfate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tranylcypromine Sulfate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Tranylcypromine Sulfate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

    Tranylcypromine Sulfate Suppliers

    A Tranylcypromine Sulfate supplier is an individual or a company that provides Tranylcypromine Sulfate active pharmaceutical ingredient (API) or Tranylcypromine Sulfate finished formulations upon request. The Tranylcypromine Sulfate suppliers may include Tranylcypromine Sulfate API manufacturers, exporters, distributors and traders.

    click here to find a list of Tranylcypromine Sulfate suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

    Tranylcypromine Sulfate USDMF

    A Tranylcypromine Sulfate DMF (Drug Master File) is a document detailing the whole manufacturing process of Tranylcypromine Sulfate active pharmaceutical ingredient (API) in detail. Different forms of Tranylcypromine Sulfate DMFs exist exist since differing nations have different regulations, such as Tranylcypromine Sulfate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Tranylcypromine Sulfate DMF submitted to regulatory agencies in the US is known as a USDMF. Tranylcypromine Sulfate USDMF includes data on Tranylcypromine Sulfate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Tranylcypromine Sulfate USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Tranylcypromine Sulfate suppliers with USDMF on PharmaCompass.

    Tranylcypromine Sulfate WC

    A Tranylcypromine Sulfate written confirmation (Tranylcypromine Sulfate WC) is an official document issued by a regulatory agency to a Tranylcypromine Sulfate manufacturer, verifying that the manufacturing facility of a Tranylcypromine Sulfate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Tranylcypromine Sulfate APIs or Tranylcypromine Sulfate finished pharmaceutical products to another nation, regulatory agencies frequently require a Tranylcypromine Sulfate WC (written confirmation) as part of the regulatory process.

    click here to find a list of Tranylcypromine Sulfate suppliers with Written Confirmation (WC) on PharmaCompass.

    Tranylcypromine Sulfate GMP

    Tranylcypromine Sulfate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Tranylcypromine Sulfate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Tranylcypromine Sulfate GMP manufacturer or Tranylcypromine Sulfate GMP API supplier for your needs.

    Tranylcypromine Sulfate CoA

    A Tranylcypromine Sulfate CoA (Certificate of Analysis) is a formal document that attests to Tranylcypromine Sulfate's compliance with Tranylcypromine Sulfate specifications and serves as a tool for batch-level quality control.

    Tranylcypromine Sulfate CoA mostly includes findings from lab analyses of a specific batch. For each Tranylcypromine Sulfate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Tranylcypromine Sulfate may be tested according to a variety of international standards, such as European Pharmacopoeia (Tranylcypromine Sulfate EP), Tranylcypromine Sulfate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tranylcypromine Sulfate USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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