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Disorder","therapeuticArea":"Psychiatry\/Psychology","highestDevelopmentStatus":"Approved","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"April 2024","url1":"","url2":"","graph1":"Psychiatry\/Psychology","graph2":"Approved"}]
Find Clinical Drug Pipeline Developments & Deals by Vanda Pharmaceuticals
Fanapt (iloperidone) is an atypical antipsychotic agent indicated for the acute treatment of manic or mixed episodes associated with bipolar I disorder in adults.
Hetlioz (tasimelteon) is a melatonin receptor agonist. It is being evaluated in Phase 3 clinical trials for the treatment of insomnia characterized by difficulties with sleep initiation.
VTR-297 (trichostatin A) is a small molecule histone deacetylase (HDAC) inhibitor with activity against dermatophytes and fungi. It is being evaluated in phase 2 clinical trials for the treatment of Onychomycosis.
VCA-894A (2'-O-methoxyethyl Phosphorothioate Oligonucleotide Sodium) specifically targets a cryptic splice site variant within immunoglobulin mu-binding protein 2 (IGHMBP2). It is being evaluated in preclinical studies for Charcot-Marie-Tooth Disease, Type 2S.
Lead Product(s):
2\'-O-methoxyethyl Phosphorothioate Oligonucleotide Sodium
Through the acquisition, Vanda expands its commercial portfolio by including Ponvory (ponesimod), a daily oral selective sphingosine-1-phosphate receptor 1 (S1P1R) modulator, indicated to treat adults with relapsing forms of multiple sclerosis.
VLY-686 (tradipitant) is an NK1R Inhibitor small molecule drug candidate, which is currently being evaluated for the treatment of gastroparesis via oral capsule.
VCA-894A is a novel antisense oligonucleotide Candidate for the Treatment of Charcot-Marie-Tooth Disease, Type 2S with a mechanism of action that specifically targets a cryptic splice site variant within immunoglobulin mu-binding protein 2 (IGHMBP2).
VLY-686 (tradipitant) is a neurokinin-1 receptor antagonist licensed by Vanda from Eli Lilly and Company. Tradipitant is currently in clinical development for gastroparesis and motion sickness.
Fanapt® (iloperidone tablets), a novel atypical antipsychotic, in the treatment of acute manic and mixed episodes associated with bipolar I disorder in adults. Fanapt® is currently approved by the FDA for the treatment of schizophrenia in adults.
HETLIOZ® (tasimelteon), is a melatonin receptor agonist that is FDA approved for both Non-24-Hour Sleep-Wake Disorder (a serious, chronic circadian rhythm disorder) and nighttime sleep disturbances in Smith-Magenis Syndrome (SMS) in patients 16 years of age and older.
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