

Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Ubidecarenone
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
BPGbio Receives FDA Pediatric Disease Designation for Epidermolysis Bullosa Treatment
Details : BPM31510T (benzoquinone ubidecarenone) is an investigational treatment for epidermolysis bullosa (EB), received Rare Pediatric Disease Designation for respective indication.
Product Name : Undisclosed
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
October 31, 2024
Lead Product(s) : Ubidecarenone
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ubidecarenone,Temozolomide,Vitamin K1
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Berg Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BPM 31510, the company’s lead drug candidate, acts by targeting the mitochondrial machinery and tumor microenvironment (TME) to create a metabolic shift in cancer cells, leading to cancer cell death.
Product Name : Undisclosed
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
June 06, 2023
Lead Product(s) : Ubidecarenone,Temozolomide,Vitamin K1
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Berg Health
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ubidecarenone
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Debra of America
Deal Size : Undisclosed
Deal Type : Partnership
Details : The collaboration is for BPGbio’s BPM 31510 for Epidermolysis Bullosa Phase II/III trial. Debra of America will provide support to awareness, understanding, and key information towards patient recruitment and advocacy for the clinical trial.
Product Name : Undisclosed
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Undisclosed
March 27, 2023
Lead Product(s) : Ubidecarenone
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Debra of America
Deal Size : Undisclosed
Deal Type : Partnership

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Lead Product(s) : Ubidecarenone,Temozolomide,Vitamin K1
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Abstract titled "Comprehensive molecular pharmacodynamic assessment identifies response markers of intermediary metabolism associated with BPM31510-IV treatment in advanced glioblastoma multiforme patients" will be presented at the ASCO meeting.
Product Name : Undisclosed
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
June 02, 2021
Lead Product(s) : Ubidecarenone,Temozolomide,Vitamin K1
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ubidecarenone,Temozolomide,Vitamin K1
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
BERG To Conduct Phase Two Trial For Treatment Of Deadly Glioblastoma Multiforme [GBM]
Details : Preclinical evidence in an aggressive orthotopic model of GBM suggests that pre-treatment (priming) followed by co-administration of BPM31510 in combination with standard of care, such as radiation and chemotherapy, led to an increase overall survival ra...
Product Name : Undisclosed
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
March 22, 2021
Lead Product(s) : Ubidecarenone,Temozolomide,Vitamin K1
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ubidecarenone
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : AdventHealth
Deal Size : Undisclosed
Deal Type : Collaboration
BERG Deepens Research Collaboration With AdventHealth To Advance Aging, Metabolism and Nash Research
Details : The partnership is comprised of separate investigations that employ BERG’s Interrogative Biology® platform to examine potential biomarker signatures of age-related disease. This also includes Phase II trial of BPM31510 on platelet and skeletal muscle ...
Product Name : Undisclosed
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Undisclosed
December 15, 2020
Lead Product(s) : Ubidecarenone
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : AdventHealth
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Ubidecarenone,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BPM 31510-IV (ubidecarenone) also known as coenzyme Q10 used in advanced refractory pancreatic ductal adenocarcinoma and identified two potential biomarkers overall survival and progressive disease.
Product Name : Undisclosed
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
September 18, 2020
Lead Product(s) : Ubidecarenone,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ubidecarenone,Temozolomide,Vitamin K1
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The study, presented at the 2020 American Society of Clinical Oncology Annual Meeting (ASCO), highlights safety, tolerability and the impact of BPM 31510-IV influence on metabolism in patients, supporting planned Phase 2 clinical development.
Product Name : Undisclosed
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
June 01, 2020
Lead Product(s) : Ubidecarenone,Temozolomide,Vitamin K1
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ubidecarenone,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Initial results showed efficacy in patient's refractory to chemotherapy regimens and identification of potential biomarkers of survival guided by the use of the BERG Interrogative Biology® platform.
Product Name : Undisclosed
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
January 27, 2020
Lead Product(s) : Ubidecarenone,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
