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\/ Jefferies"},{"orgOrder":0,"company":"Travere Therapeutics","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Public Offering","leadProduct":"Sparsentan","moa":"Endothelin A receptor\/Angiotensin II subtype-1 receptor","graph1":"Nephrology","graph2":"Approved FDF","graph3":"Travere Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Travere Therapeutics \/ Jefferies","highestDevelopmentStatusID":"15","companyTruncated":"Travere Therapeutics \/ Jefferies"},{"orgOrder":0,"company":"Travere Therapeutics","sponsor":"Ligand Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Sparsentan","moa":"Endothelin A receptor\/Angiotensin II subtype-1 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Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"Travere Therapeutics \/ Ligand Pharmaceuticals"},{"orgOrder":0,"company":"Travere Therapeutics","sponsor":"Renalys Pharma","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Licensing Agreement","leadProduct":"Sparsentan","moa":"Endothelin A receptor\/Angiotensin II subtype-1 receptor","graph1":"Nephrology","graph2":"Approved FDF","graph3":"Travere Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Travere Therapeutics \/ Renalys Pharma","highestDevelopmentStatusID":"15","companyTruncated":"Travere Therapeutics \/ Renalys Pharma"},{"orgOrder":0,"company":"Travere Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small 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Tablet","sponsorNew":"Travere Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Travere Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Travere Therapeutics","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Public Offering","leadProduct":"Sparsentan","moa":"Endothelin A receptor\/Angiotensin II subtype-1 receptor","graph1":"Nephrology","graph2":"Approved FDF","graph3":"Travere Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Travere Therapeutics \/ Jefferies","highestDevelopmentStatusID":"15","companyTruncated":"Travere Therapeutics \/ Jefferies"},{"orgOrder":0,"company":"Travere Therapeutics","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small 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Therapeutics","sponsor":"CSL Vifor","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Sparsentan","moa":"Endothelin A receptor\/Angiotensin II subtype-1 receptor","graph1":"Nephrology","graph2":"Phase III","graph3":"Travere Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Travere Therapeutics \/ CSL Vifor","highestDevelopmentStatusID":"10","companyTruncated":"Travere Therapeutics \/ CSL Vifor"},{"orgOrder":0,"company":"Travere Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Sparsentan","moa":"Endothelin A receptor\/Angiotensin II subtype-1 receptor","graph1":"Nephrology","graph2":"Phase 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Diseases","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Orphan Technologies \/ Travere Therapeutics","highestDevelopmentStatusID":"7","companyTruncated":"Orphan Technologies \/ Travere Therapeutics"},{"orgOrder":0,"company":"Orphan Technologies","sponsor":"Travere Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Rare Diseases and Disorders","country":"SWITZERLAND","productType":"Enzyme","year":"2020","type":"Acquisition","leadProduct":"OT-58","moa":"Undisclosed","graph1":"Rare Diseases and Disorders","graph2":"Phase I\/ Phase II","graph3":"Orphan Technologies","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Orphan Technologies \/ Travere Therapeutics","highestDevelopmentStatusID":"7","companyTruncated":"Orphan Technologies \/ Travere Therapeutics"},{"orgOrder":0,"company":"Travere Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Sparsentan","moa":"ETA\/AT1 receptor","graph1":"Nephrology","graph2":"Phase III","graph3":"Travere Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Travere Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Travere Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Travere Therapeutics","sponsor":"CSL Vifor","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Sparsentan","moa":"ETA\/AT1 receptor","graph1":"Nephrology","graph2":"Approved FDF","graph3":"Travere Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Travere Therapeutics \/ CSL Vifor","highestDevelopmentStatusID":"15","companyTruncated":"Travere Therapeutics \/ CSL Vifor"},{"orgOrder":0,"company":"Travere Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Sparsentan","moa":"ETA\/AT1 receptor","graph1":"Nephrology","graph2":"Phase III","graph3":"Travere Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Travere Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Travere Therapeutics \/ Inapplicable"}]

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                          01

                          Hospitalar
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                          Details : Filspari (sparsentan) is an oral drug designed to selectively target two critical pathways - endothelin-1 and angiotensin II. It is indicated for the treatment of focal segmental glomerulosclerosis.

                          Product Name : Filspari

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 15, 2025

                          Lead Product(s) : Sparsentan

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Hospitalar
                          Not Confirmed
                          Hospitalar
                          Not Confirmed

                          Details : Filspari (sparsentan) is an oral drug designed to selectively target two critical pathways - endothelin-1 and angiotensin II. It is approved for the treatment of IgA Nephropathy.

                          Product Name : Filspari

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 29, 2025

                          Lead Product(s) : Sparsentan

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : CSL Vifor

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Hospitalar
                          Not Confirmed
                          Hospitalar
                          Not Confirmed

                          Details : Filspari (sparsentan) is an oral drug designed to selectively target two critical pathways - endothelin-1 and angiotensin II. It is approved for the treatment of focal segmental glomerulosclerosis.

                          Product Name : Filspari

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 17, 2025

                          Lead Product(s) : Sparsentan

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Hospitalar
                          Not Confirmed
                          Hospitalar
                          Not Confirmed

                          Details : Filspari (sparsentan) is an oral drug designed to selectively target two critical pathways - endothelin-1 and angiotensin II. It is approved for the treatment of focal segmental glomerulosclerosis.

                          Product Name : Filspari

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 11, 2025

                          Lead Product(s) : Sparsentan

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Hospitalar
                          Not Confirmed
                          Hospitalar
                          Not Confirmed

                          Details : The company intends to use the net proceeds for commercialization expenses of its products including Filspari (sparsentan) used for the treatment of adults with primary immunoglobulin A nephropathy.

                          Product Name : Filspari

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 11, 2024

                          Lead Product(s) : Sparsentan

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Jefferies

                          Deal Size : $143.8 million

                          Deal Type : Public Offering

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                          06

                          Hospitalar
                          Not Confirmed
                          Hospitalar
                          Not Confirmed

                          Details : Filspari (sparsentan) is an oral medication targeting endothelin-1 and angiotensin II pathways in IgAN, approved for treating IgA nephropathy.

                          Product Name : Filspari

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 03, 2024

                          Lead Product(s) : Sparsentan

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Hospitalar
                          Not Confirmed
                          Hospitalar
                          Not Confirmed

                          Details : Filspari (sparsentan) is a once-daily approved oral medication, designed to selectively target two critical pathways in the disease progression of IgAN (endothelin-1 and angiotensin II).

                          Product Name : Filspari

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 17, 2024

                          Lead Product(s) : Sparsentan

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Vifor Pharma

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Hospitalar
                          Not Confirmed
                          Hospitalar
                          Not Confirmed

                          Details : TVT-058 (pegtibatinase) is a novel investigational enzyme replacement therapy which is being evaluated in phase 3 clinical trials for the treatment of classical homocystinuria (HCU).

                          Product Name : TVT-058

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          September 26, 2024

                          Lead Product(s) : Pegtibatinase

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Hospitalar
                          Not Confirmed
                          Hospitalar
                          Not Confirmed

                          Details : The company intends to use the net proceeds for commercialization expenses of its products including Filspari (sparsentan) used for the treatment of adults with primary immunoglobulin A nephropathy.

                          Product Name : Filspari

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          July 11, 2024

                          Lead Product(s) : Sparsentan

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Jefferies

                          Deal Size : Undisclosed

                          Deal Type : Public Offering

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                          10

                          Hospitalar
                          Not Confirmed
                          Hospitalar
                          Not Confirmed

                          Details : The company intends to use the net proceeds for commercialization expenses of its products including Filspari (sparsentan) used for the treatment of adults with primary immunoglobulin A nephropathy.

                          Product Name : Filspari

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          July 11, 2024

                          Lead Product(s) : Sparsentan

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Jefferies

                          Deal Size : $125.0 million

                          Deal Type : Public Offering

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