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Diseases","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Tonix Pharmaceuticals Holding Corp","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tonix Pharmaceuticals Holding Corp \/ Tonix Pharmaceuticals Holding Corp","highestDevelopmentStatusID":"4","companyTruncated":"Tonix Pharmaceuticals Holding Corp \/ Tonix Pharmaceuticals Holding Corp"},{"orgOrder":0,"company":"Tonix Pharmaceuticals Holding Corp","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Tonix Pharmaceuticals Holding Corp","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tonix Pharmaceuticals Holding Corp \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"Tonix Pharmaceuticals Holding Corp \/ Undisclosed"},{"orgOrder":0,"company":"Tonix Pharmaceuticals Holding Corp","sponsor":"US Department of Defense","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Discovery","graph3":"Tonix Pharmaceuticals Holding Corp","amount2":0.029999999999999999,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.029999999999999999,"dosageForm":"Undisclosed","sponsorNew":"Tonix Pharmaceuticals Holding Corp \/ US Department of Defense","highestDevelopmentStatusID":"2","companyTruncated":"Tonix Pharmaceuticals Holding Corp \/ US Department of Defense"},{"orgOrder":0,"company":"Tonix Pharmaceuticals Holding Corp","sponsor":"Tonix Pharmaceuticals Holding Corp","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2025","type":"Licensing Agreement","leadProduct":"TNX-4800","moa":"OspA","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Tonix Pharmaceuticals Holding Corp","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Tonix Pharmaceuticals Holding Corp \/ Tonix Pharmaceuticals Holding Corp","highestDevelopmentStatusID":"6","companyTruncated":"Tonix Pharmaceuticals Holding Corp \/ Tonix Pharmaceuticals Holding Corp"}]

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                            01

                            Tonix Pharmaceuticals Holding Corp

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                            Tonix Pharmaceuticals Holding Corp

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                            Lead Product(s) : TNX-4800

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Recipient : UMass Chan Medical School

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Tonix Announces In-licensing Phase 2/3-Ready Monoclonal Antibody

                            Details : Tonix is in-licensing of worldwide rights to TNX-4800 (mAb 2217LS)1, which is a long-acting human monoclonal antibody that targets the outer surface protein A (OspA) of Borrelia burgdorferi.

                            Product Name : TNX-4800

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            September 17, 2025

                            Lead Product(s) : TNX-4800

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Recipient : UMass Chan Medical School

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            02

                            Tonix Pharmaceuticals Holding Corp

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                            Tonix Pharmaceuticals Holding Corp

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                            Lead Product(s) : Cyclobenzaprine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Approves Tonix’s Tonmya For Fibromyalgia Treatment

                            Details : Tonmya (cyclobenzaprine HCl) is an antagonism of 5-HT2A, alpha-1-adrenergic, H1-histaminergic, and M1-muscarinic acetylcholine receptors, indicated for the treatment of fibromyalgia in adults

                            Product Name : Tonmya

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 15, 2025

                            Lead Product(s) : Cyclobenzaprine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Tonix Pharmaceuticals Holding Corp

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                            Lead Product(s) : 13-N Oxytocin

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Recipient : Aarhus University Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            First-in-man Imaging of a New PET Radiotracer for Oxytocin Receptors

                            Details : 13-N Oxytocin is a Radiolabeled Compounds drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Facial Pain.

                            Product Name : Undisclosed

                            Product Type : Radiolabeled Compound

                            Upfront Cash : Inapplicable

                            May 02, 2025

                            Lead Product(s) : 13-N Oxytocin

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Recipient : Aarhus University Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Tonix Pharmaceuticals Holding Corp

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                            Tonix Pharmaceuticals Holding Corp

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                            Lead Product(s) : TNX-1500,Undisclosed

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Makana Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Tonix, Makana Partner On Anti-CD40L Antibody and Xenotransplantation

                            Details : Tonix and Makana will study Tonix’s anti-CD40L monoclonal antibody candidate, TNX-1500, in combination with Makana’s human-compatible organs and cells for the treatment of organ failure.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            April 09, 2025

                            Lead Product(s) : TNX-1500,Undisclosed

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Makana Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            05

                            Tonix Pharmaceuticals Holding Corp

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                            Tonix Pharmaceuticals Holding Corp

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                            Lead Product(s) : Tnx-801

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Medical CBRN Defense Consortium

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Tonix Pharmaceuticals Announces Grant by MCDC for Development of TNX-801

                            Details : The funding will be used to support the development of TNX-801 (recombinant horsepox virus, live vaccine), the company’s single-dose mpox and smallpox vaccine candidate.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            March 10, 2025

                            Lead Product(s) : Tnx-801

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Medical CBRN Defense Consortium

                            Deal Size : Undisclosed

                            Deal Type : Funding

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                            06

                            Tonix Pharmaceuticals Holding Corp

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                            Lead Product(s) : TNX-1500

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tonix Reports Positive Phase 1 Results for TNX-1500 in Kidney Transplant Rejection

                            Details : TNX-1500 is a Fc-modified humanized anti-CD40L monoclonal antibody that interacts with the CD40-ligand, which is being evaluated for the treatment of organ transplant rejection.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            February 06, 2025

                            Lead Product(s) : TNX-1500

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Tonix Pharmaceuticals Holding Corp

                            U.S.A arrow
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                            Tonix Pharmaceuticals Holding Corp

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                            Lead Product(s) : Cyclobenzaprine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tonix Announces August 2025 PDUFA Date for TNX-102 SL Fibromyalgia Decision

                            Details : TNX-102 SL is a centrally acting, non-opioid bedtime investigational drug, designed for chronic use. It is being evaluated for the treatment of Fibromyalgia.

                            Product Name : Tonmya

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 23, 2024

                            Lead Product(s) : Cyclobenzaprine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Tonix Pharmaceuticals Holding Corp

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                            Lead Product(s) : Cyclobenzaprine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tonix Receives NDA Acceptance for TNX-102 SL To Treat Fibromyalgia

                            Details : TNX-102 SL is a centrally acting, non-opioid bedtime investigational drug, designed for chronic use. It is being evaluated for the treatment of Fibromyalgia.

                            Product Name : Tonmya

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 17, 2024

                            Lead Product(s) : Cyclobenzaprine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Tonix Pharmaceuticals Holding Corp

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                            Lead Product(s) : Tnx-801

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : KEMRI

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Tonix And KEMRI Partner for Phase I TNX-801 Study for Mpox

                            Details : under the agreement, Tonix will be the sponsor and KEMRI will lead the execution of the proposed clinical trial TNX-801, vaccine for the treatment of Mpox.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            November 04, 2024

                            Lead Product(s) : Tnx-801

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : KEMRI

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            10

                            Tonix Pharmaceuticals Holding Corp

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Discovery

                            Sponsor : US Department of Defense

                            Deal Size : $34.0 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Tonix Gets U.S. Defense Contract for Broad-Spectrum Antiviral Development

                            Details : The agreement aims to develop small molecule broad-spectrum antiviral agents for the treatment of infections to improve the medical readiness of military personnel in biological threat environments.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            October 17, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Discovery

                            Sponsor : US Department of Defense

                            Deal Size : $34.0 million

                            Deal Type : Agreement

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