[{"orgOrder":0,"company":"Tilde Sciences","sponsor":"Vyera Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Cytotoxic Drug","year":"2023","type":"Acquisition","leadProduct":"Pyrimethamine","moa":"Dihydrofolate reductase","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Tilde Sciences","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Tilde Sciences \/ Tilde Sciences","highestDevelopmentStatusID":"15","companyTruncated":"Tilde Sciences \/ Tilde Sciences"},{"orgOrder":0,"company":"Tilde Sciences","sponsor":"Washington University School of Medicine","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2023","type":"Inapplicable","leadProduct":"Pyrimethamine","moa":"Dihydrofolate reductase","graph1":"Oncology","graph2":"Phase I","graph3":"Tilde Sciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Tilde Sciences \/ Tilde Sciences","highestDevelopmentStatusID":"6","companyTruncated":"Tilde Sciences \/ Tilde Sciences"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Through the acquisition, Tilda Sciences gain two medicines, Daraprim (pyrimethamine), approved for treatment of toxoplasmosis and Vecamyl (mecamylamine HCI), approved for management of hypertension, from Vyera Pharmaceuticals.

                          Product Name : Daraprim

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Undisclosed

                          July 12, 2023

                          Lead Product(s) : Pyrimethamine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Recipient : Vyera Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          02

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          January 10, 2023

                          Lead Product(s) : Pyrimethamine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Washington University School of Medicine

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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