[{"orgOrder":0,"company":"Amgen Inc","sponsor":"Volastra Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Licensing Agreement","leadProduct":"Sovilnesib","moa":"KIF18A","graph1":"Oncology","graph2":"Phase I","graph3":"Amgen Inc","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Amgen Inc \/ Volastra Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Amgen Inc \/ Volastra Therapeutics"},{"orgOrder":0,"company":"Volastra Therapeutics","sponsor":"Polaris Partners","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Series A Financing","leadProduct":"Sovilnesib","moa":"KIF18A","graph1":"Oncology","graph2":"Phase I","graph3":"Volastra Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Volastra Therapeutics \/ Polaris Partners","highestDevelopmentStatusID":"6","companyTruncated":"Volastra Therapeutics \/ Polaris Partners"},{"orgOrder":0,"company":"Volastra Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Sovilnesib","moa":"KIF18A","graph1":"Oncology","graph2":"Phase I","graph3":"Volastra Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Volastra Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Volastra Therapeutics \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals for Sovilnesib

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmacy Expo
                          Not Confirmed
                          Pharmacy Expo
                          Not Confirmed

                          Details : AMG-650 (sovilnesib) is a KIF18A inhibitor, small molecule drug, which is being evaluated for the treatment of patients with platinum-resistant or refractory high-grade serous ovarian cancer.

                          Product Name : AMG 650

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 16, 2024

                          Lead Product(s) : Sovilnesib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Pharmacy Expo
                          Not Confirmed
                          Pharmacy Expo
                          Not Confirmed

                          Details : Under the terms of the licensing agreement, Volastra receives an exclusive worldwide license (ex-China) to develop and commercialize AMG650 (sovilnesib), an oral, first-in-class small molecule inhibitor of KIF18A.

                          Product Name : AMG 650

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          July 03, 2023

                          Lead Product(s) : Sovilnesib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Volastra Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          Pharmacy Expo
                          Not Confirmed
                          Pharmacy Expo
                          Not Confirmed

                          Details : The Funding will support clinical development of Volastra’s portfolio of KIF18A inhibitors including, AMG650 (sovilnesib), an oral, first-in-class small molecule, as well as advancement of a robust pipeline of research programs targeting chromosomally ...

                          Product Name : AMG 650

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          July 03, 2023

                          Lead Product(s) : Sovilnesib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Polaris Partners

                          Deal Size : $60.0 million

                          Deal Type : Series A Financing

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