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Conjugate","year":"2021","type":"Inapplicable","leadProduct":"Loncastuximab Tesirine","moa":"B-lymphocyte antigen CD19 | DNA","graph1":"Oncology","graph2":"Approved FDF","graph3":"ADC Therapeutics","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ADC Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"ADC Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"ADC Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Antibody-drug Conjugate","year":"2021","type":"Inapplicable","leadProduct":"Loncastuximab Tesirine","moa":"B-lymphocyte antigen CD19 | DNA","graph1":"Oncology","graph2":"Phase II","graph3":"ADC Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"ADC Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"ADC Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Mayur Narkhede","sponsor":"ADC Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Antibody-drug Conjugate","year":"2023","type":"Inapplicable","leadProduct":"Loncastuximab Tesirine","moa":"B-lymphocyte antigen CD19 | DNA","graph1":"Oncology","graph2":"Phase I","graph3":"Mayur Narkhede","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Mayur Narkhede \/ ADC Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Mayur Narkhede \/ ADC Therapeutics"}]

Find Clinical Drug Pipeline Developments & Deals for Loncastuximab Tesirine

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                          01

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : ADC Therapeutics intends to use the net proceeds to fund multiple catalysts primarily in support of Zynlonta (loncastuximab tesirine) clinical development as well as commercialization activities.

                          Product Name : Zynlonta

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          June 12, 2025

                          Lead Product(s) : Loncastuximab Tesirine

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Redmile Group

                          Deal Size : $100.0 million

                          Deal Type : Private Placement

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                          02

                          University of Utah

                          Country arrow
                          EPSC
                          Not Confirmed

                          University of Utah

                          Country arrow
                          EPSC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          January 23, 2025

                          Lead Product(s) : Loncastuximab Tesirine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : ADC Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Zynlonta (loncastuximab tesirine), an antibody-drug conjugate (ADC) targeting CD19, is is being investigated for the treatment of adult patients with relapsed/refractory (r/r) marginal zone lymphoma.

                          Product Name : Zynlonta

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          December 30, 2024

                          Lead Product(s) : Loncastuximab Tesirine,Gemcitabine,Rituximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Zynlonta (loncastuximab tesirine) is a CD19-directed ADC, which is being evaluated in combination with glofitamab & obinutuzumab for the treatment of relapsed/refractory B-cell non-Hodgkin lymphoma.

                          Product Name : Zynlonta

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          December 11, 2024

                          Lead Product(s) : Loncastuximab Tesirine,Glofitamab,Obinutuzumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          University of Utah

                          Country arrow
                          EPSC
                          Not Confirmed

                          University of Utah

                          Country arrow
                          EPSC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          September 23, 2024

                          Lead Product(s) : Loncastuximab Tesirine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : ADC Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Zynlonta (loncastuximab tesirine), an antibody-drug conjugate (ADC) targeting CD19, is is being investigated for the treatment of adult patients with relapsed/refractory (r/r) marginal zone lymphoma.

                          Product Name : Zynlonta

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          June 05, 2024

                          Lead Product(s) : Loncastuximab Tesirine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The net proceeds will advance the company's CD19-directed ADC ZYNLONTA (loncastuximab tesirine-lpyl) in combination with polatuzumab vedotin for relapsed or refractory B-cell Non-Hodgkin Lymphoma.

                          Product Name : Zynlonta

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          June 05, 2024

                          Lead Product(s) : Loncastuximab Tesirine,Glofitamab,Obinutuzumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Jefferies

                          Deal Size : $105.0 million

                          Deal Type : Public Offering

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                          08

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Zynlonta (loncastuximab tesirine), a CD19-directed antibody drug conjugate, is being tested with glofitamab and obinutuzumab for relapsed/refractory B-cell non-Hodgkin lymphoma.

                          Product Name : Zynlonta

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          April 04, 2024

                          Lead Product(s) : Loncastuximab Tesirine,Glofitamab,Obinutuzumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Zynlonta (loncastuximab tesirine-lpyl), an antibody-drug conjugate (ADC) targeting CD19, is being developed in combination with rituximab in unfit or frail patients with previously untreated diffuse large B-cell lymphoma (DLBCL).

                          Product Name : Zynlonta

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          November 07, 2023

                          Lead Product(s) : Loncastuximab Tesirine,Rituximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Mayur Narkhede

                          Country arrow
                          EPSC
                          Not Confirmed

                          Mayur Narkhede

                          Country arrow
                          EPSC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          August 02, 2023

                          Lead Product(s) : Loncastuximab Tesirine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : ADC Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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