Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
LegoChemBio Joins Hands with Orion to Become a Global Top ADC Company
Details : The net proceeds will be used to advance Lego's ADC pipeline including, LCB14, an antibody-drug conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2).
Product Name : IKS014
Product Type : Antibody-drug Conjugate
Upfront Cash : Undisclosed
January 16, 2024
Lead Product(s) : LCB84,Undisclosed
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Janssen Biotech
Deal Size : $1,700.0 million
Deal Type : Licensing Agreement
LegoChem Biosciences Announces License Agreement for LCB84 Trop2-Targeted ADC
Details : Under the terms of the agreement, LCB will grant Janssen an exclusive, worldwide license for the development and commercialization of LCB84, a Trop2 directed ADC which is currently being investigated for advanced solid tumors.
Product Name : LCB84
Product Type : Other Large Molecule
Upfront Cash : $100.0 million
December 26, 2023
Lead Product(s) : LCB84,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Janssen Biotech
Deal Size : $1,700.0 million
Deal Type : Licensing Agreement
Lead Product(s) : LCB84,Undisclosed
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : BostonGene
Deal Size : Undisclosed
Deal Type : Collaboration
LegoChem Biosciences Selects BostonGene as Genomic Partner for First-in-Human Clinical Trial
Details : Under the collaboration, BostonGene will support the Phase I/II study of LCB84, a TROP2-directed antibody-drug conjugate (ADC), in patients with advanced cancers.
Product Name : LCB84
Product Type : Other Large Molecule
Upfront Cash : Undisclosed
July 11, 2023
Lead Product(s) : LCB84,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : BostonGene
Deal Size : Undisclosed
Deal Type : Collaboration
Details : LCB’s clinical-stage ConjuAll Antibody Drug Conjugates (ADC) technology platform provides optimized site-specific conjugation, as well as cancer-selectively activating linker and payload technologies for ADCs.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Undisclosed
December 23, 2022
Details : Glycotope’s antibodies target specific tumor-associated carbohydrate structures or protein/carbohydrate combined glyco-epitopes (GT-00X). Targeting these specific antigens enables broad indication range, long-term treatment potential and reduced on-tar...
Product Name : GT-00X
Product Type : Undisclosed
Upfront Cash : Undisclosed
December 07, 2022
Details : Under the terms of the multi-target agreement, SOTIO will be responsible for research, development, manufacturing and commercialization of the ADC products, while LCB will support SOTIO for the research activities and the manufacturing of its products in...
Product Name : LCB20A
Product Type : Other Large Molecule
Upfront Cash : Undisclosed
November 16, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : Iksuda Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Expanded agreement grants Iksuda access to LegoChem Biosciences’ next generation ADC platform for up to six targets. Iksuda also gains access to LegoChem Biosciences’ new payload, supplementing the tumour-activated payloads accessed in 2020.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
June 22, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : Iksuda Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : LCB71
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : CStone Pharmaceuticals
Deal Size : $353.5 million
Deal Type : Licensing Agreement
CStone and LegoChem Biosciences Enter Global Licensing Agreement for New Antibody Drug Conjugate
Details : CStone obtains the exclusive global right to lead development and commercialization of LCB71 outside the Republic of Korea. LCB71 is a pre-clinical ADC entering into Investigational New Drug (IND) enabling studies.
Product Name : LCB71
Product Type : Antibody-drug Conjugate
Upfront Cash : $10.0 million
October 29, 2020
Lead Product(s) : LCB71
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : CStone Pharmaceuticals
Deal Size : $353.5 million
Deal Type : Licensing Agreement
Lead Product(s) : LCB73
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Iksuda
Deal Size : $227.0 million
Deal Type : Licensing Agreement
LegoChem Biosciences and Iksuda Enter Licensing Agreement for Antibody Drug Conjugate Program
Details : LCB73 has been generated in a partnership between LCB and Swiss-based Light Chain Bioscience’s (Novimmune SA) by combining LCB’s cancer-selectively activated next-generation linker and toxin platform with Light Chain Bioscience’s proprietary antibo...
Product Name : LCB73
Product Type : Antibody-drug Conjugate
Upfront Cash : $5.0 million
May 15, 2020
Lead Product(s) : LCB73
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Iksuda
Deal Size : $227.0 million
Deal Type : Licensing Agreement
Details : The agreement grants Iksuda an access to Legochem Biosciences’ next-generation payload and proprietary linker to discover and advance lead ADC for difficult-to-treat tumours.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
April 16, 2020