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                          OPRD
                          Not Confirmed

                          Details : Through the acquisition, Pharmacosmos will leverage G1' intellectual property and the addition of Cosela (trilaciclib), which is indicated for treating metastatic triple-negative breast cancer.

                          Product Name : Cosela

                          Product Type : Miscellaneous

                          Upfront Cash : $405.0 million

                          August 07, 2024

                          Lead Product(s) : Trilaciclib

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Pharmacosmos AS

                          Deal Size : $405.0 million

                          Deal Type : Acquisition

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                          02

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Cosela (trilaciclib) is being evaluated in combination with chemotherapeutic drugs gemcitabine and carboplatin in patients with metastatic metastatic triple negative breast cancer.

                          Product Name : Cosela

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 24, 2024

                          Lead Product(s) : Trilaciclib,Carboplatin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Cosela (trilaciclib) CDK4/CDK6 inhibitor is being evaluated in combination with a TROP2 ADC sacituzumab govitecan for the treatment of Triple Negative Breast Cancer.

                          Product Name : Cosela

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 28, 2024

                          Lead Product(s) : Trilaciclib,Sacituzumab Govitecan

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          04

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Through the license agreement, company will gain exclusive rights for the clinical development and commercialization of G1T38 (lerociclib) for radioprotection in the US, Europe etc.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          May 22, 2024

                          Lead Product(s) : Lerociclib,Fulvestrant

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Deimos Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          05

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Under the terms of the license agreement, Pepper Bio will focus on the clinical development of G1T38 (lerociclib) for the treatment of hepatocellular carcinoma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          May 01, 2024

                          Lead Product(s) : Lerociclib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Pepper Bio

                          Deal Size : $135.0 million

                          Deal Type : Licensing Agreement

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                          06

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : G1T28 (trilaciclib) is an IV-administered transient CDK 4/6 inhibitor, which is being evaluated in combination with gemcitabine & carboplatin for metastatic triple negative breast cancer.

                          Product Name : Cosela

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 12, 2024

                          Lead Product(s) : Trilaciclib,Carboplatin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Cosela (Trilaciclib hydrochloride), an IV-administered transient CDK4/6 inhibitor, is a first-in-class therapy designed to preserve bone marrow and immune system function during chemotherapy to improve patient outcomes.

                          Product Name : Cosela

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 03, 2023

                          Lead Product(s) : Trilaciclib,Carboplatin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Trilaciclib is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Small Cell Lung Carcinoma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 24, 2023

                          Lead Product(s) : Trilaciclib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : The data highlight the potential for G1T28 (trilaciclib) to meaningfully reduce adverse events related to use of sacituzumab. As expected, patients with PD-L1(+) tumors appear to respond earlier than patients with PD-L1(-) tumors.

                          Product Name : Cosela

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 10, 2023

                          Lead Product(s) : Trilaciclib,Sacituzumab Govitecan

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          OPRD
                          Not Confirmed
                          OPRD
                          Not Confirmed

                          Details : Cosela (Trilaciclib) is a CDK4 and CDK6 inhibitor, indicated to reduce the incidence of chemotherapy induced myelosuppression in patients before topotecan-containing or platinum and etoposide-containing chemotherapy for extensive stage small cell lung ca...

                          Product Name : Cosela

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 13, 2023

                          Lead Product(s) : Trilaciclib,Fluorouracil,Bevacizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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