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Find Clinical Drug Pipeline Developments & Deals for (-)-Etoposide

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                          Top Deals by Deal Size (USD bn)

                          01

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The partnership aims to expand BioNTech’s BNT327, a next-generation bispecific antibody candidate targeting PD-L1 and VEGF-A, is currently being evaluated in 1L-treatment in extensive stage SCLC.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : $1500 million

                          June 02, 2025

                          Lead Product(s) : BNT327,Etoposide,Carboplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Bristol Myers Squibb

                          Deal Size : $11,100.0 million

                          Deal Type : Partnership

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                          02

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Tevimbra (tislelizumab) is a uniquely designed humanized IgG4 PD-1 mAb, being evaluated for extensive-stage small cell lung cancer in combination with etoposide and platinum chemotherapy.

                          Product Name : Tevimbra

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          March 31, 2025

                          Lead Product(s) : Tislelizumab,Cisplatin,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : BNT327, is a PD L1/VEGF targetting antibody candidate, which is currently being evaluated for the treatment of small-cell lung cancer.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          March 28, 2025

                          Lead Product(s) : BNT327,Etoposide,Carboplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : PT217 (peluntamig) is a first-in-class native IgG-like bispecific antibody (bsAb) targeting DLL3 and CD4. It is being evaluated for the treatment of patients with neuroendocrine prostate carcinoma.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          February 19, 2025

                          Lead Product(s) : Peluntamig,Carboplatin,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Hetronifly (serplulimab) is a PD-1 inhibitor antibody approved in combination with carboplatin and etoposide as a first-line treatment of adult patients with ES-SCLC.

                          Product Name : Hetronifly

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          February 05, 2025

                          Lead Product(s) : Serplulimab,Carboplatin,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : BioNTech strengthen its oncology portfolio and obtains full global rights to the late-stage clinical asset PM8002 (BNT327), an investigational bispecific antibody targeting PD-L1 and VEGF-A.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : $800.0 million

                          February 03, 2025

                          Lead Product(s) : PM8002,Carboplatin,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : BioNTech

                          Deal Size : $950.0 million

                          Deal Type : Acquisition

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                          07

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : GMI-1271 (uproleselan) is a E-selectin inhibitor, which is being evaluated to treat adults with relapsed or refractory acute myeloid leukemia.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 20, 2024

                          Lead Product(s) : Uproleselan,Etoposide,Mitoxantrone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : LBL-024 is a tetravalent bispecific antibody that simultaneously targets PD-L1 and 4-1BB, serving dual functions. It is being evaluated for the treatment of neuroendocrine cancer.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          November 22, 2024

                          Lead Product(s) : LBL-024,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Shanghai Chest Hospital

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Shanghai Chest Hospital

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Etoposide is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Small Cell Lung Carcinoma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 21, 2024

                          Lead Product(s) : Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Jiangsu Simcere Pharmaceutical

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : GMI-1271 (uproleselan) is a E-selectin inhibitor, which is being evaluated to treat adults with newly diagnosed acute myeloid leukemia (AML) who are 60 years or older.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 29, 2024

                          Lead Product(s) : Uproleselan,Etoposide,Mitoxantrone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : The Division of Cancer Treatment and Diagnosis

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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