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Biolabs","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Cisplatin","moa":"||4-1BB\/PDL1","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Leads Biolabs","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Leads Biolabs \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Leads Biolabs \/ Inapplicable"},{"orgOrder":0,"company":"Phanes Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"Carboplatin","moa":"||DLL3\/CD47","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Phanes Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Phanes Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Phanes Therapeutics \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals for EPEG

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Socazolimab,Carboplatin,Etoposide

                          Therapeutic Area : Oncology

                          Study Phase : Phase III

                          Sponsor : Sorrento Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : ZKAB001 (Socazolimab) (anti-PD-L1 monoclonal antibody) was discovered by Sorrento from its fully human antibody G-MABTM library and licensed by China Oncology Focus Limited (“COF”), a Lee’s Pharm subsidiary, for the Great China Territories.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          May 17, 2022

                          Lead Product(s) : Socazolimab,Carboplatin,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Sorrento Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Company Banner

                          02

                          Lead Product(s) : Socazolimab,Carboplatin,Etoposide

                          Therapeutic Area : Oncology

                          Study Phase : Phase III

                          Sponsor : Sorrento Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The initiation of this Phase 3 trial is based on the very encouraging results from an earlier Phase Ib trial in which Socazolimab combined with carboplatin and etoposide showed a promising efficacy and safety profile in patients with extensive-stage smal...

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          July 23, 2021

                          Lead Product(s) : Socazolimab,Carboplatin,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Sorrento Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Company Banner

                          03

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : The partnership aims to expand BioNTech’s BNT327, a next-generation bispecific antibody candidate targeting PD-L1 and VEGF-A, is currently being evaluated in 1L-treatment in extensive stage SCLC.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : $1500 million

                          June 02, 2025

                          Lead Product(s) : BNT327,Etoposide,Carboplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Bristol Myers Squibb

                          Deal Size : $11,100.0 million

                          Deal Type : Partnership

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                          04

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : Tevimbra (tislelizumab) is a uniquely designed humanized IgG4 PD-1 mAb, being evaluated for extensive-stage small cell lung cancer in combination with etoposide and platinum chemotherapy.

                          Product Name : Tevimbra

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          March 31, 2025

                          Lead Product(s) : Tislelizumab,Cisplatin,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : BNT327, is a PD L1/VEGF targetting antibody candidate, which is currently being evaluated for the treatment of small-cell lung cancer.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          March 28, 2025

                          Lead Product(s) : BNT327,Etoposide,Carboplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : PT217 (peluntamig) is a first-in-class native IgG-like bispecific antibody (bsAb) targeting DLL3 and CD4. It is being evaluated for the treatment of patients with neuroendocrine prostate carcinoma.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          February 19, 2025

                          Lead Product(s) : Peluntamig,Carboplatin,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : Hetronifly (serplulimab) is a PD-1 inhibitor antibody approved in combination with carboplatin and etoposide as a first-line treatment of adult patients with ES-SCLC.

                          Product Name : Hetronifly

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          February 05, 2025

                          Lead Product(s) : Serplulimab,Carboplatin,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : BioNTech strengthen its oncology portfolio and obtains full global rights to the late-stage clinical asset PM8002 (BNT327), an investigational bispecific antibody targeting PD-L1 and VEGF-A.

                          Product Name : Undisclosed

                          Product Type : Other Large Molecule

                          Upfront Cash : $800.0 million

                          February 03, 2025

                          Lead Product(s) : PM8002,Carboplatin,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : BioNTech

                          Deal Size : $950.0 million

                          Deal Type : Acquisition

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                          09

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : GMI-1271 (uproleselan) is a E-selectin inhibitor, which is being evaluated to treat adults with relapsed or refractory acute myeloid leukemia.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 20, 2024

                          Lead Product(s) : Uproleselan,Etoposide,Mitoxantrone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : LBL-024 is a tetravalent bispecific antibody that simultaneously targets PD-L1 and 4-1BB, serving dual functions. It is being evaluated for the treatment of neuroendocrine cancer.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 22, 2024

                          Lead Product(s) : LBL-024,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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