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III","therapeuticAreaShortName":"Oncology","amount2New":0.01,"dosageForm":"Intratumoral Injection","sponsorNew":"CEL-SCI \/ Thinkequity","highestDevelopmentStatusID":"10","companyTruncated":"CEL-SCI \/ Thinkequity"},{"orgOrder":0,"company":"Brooklyn ImmunoTherapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2022","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"||IL-2 receptor","graph1":"Oncology","graph2":"Phase II","graph3":"Brooklyn ImmunoTherapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Brooklyn ImmunoTherapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Brooklyn ImmunoTherapeutics \/ Inapplicable"},{"orgOrder":0,"company":"CEL-SCI","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"Interleukin 2","moa":"||T-cell receptor","graph1":"Oncology","graph2":"Phase III","graph3":"CEL-SCI","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Peritumoral Injection","sponsorNew":"CEL-SCI \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"CEL-SCI \/ Inapplicable"},{"orgOrder":0,"company":"CEL-SCI","sponsor":"Thinkequity","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2025","type":"Public Offering","leadProduct":"Interleukin 2","moa":"||T-cell receptor","graph1":"Oncology","graph2":"Phase III","graph3":"CEL-SCI","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Peritumoral Injection","sponsorNew":"CEL-SCI \/ Thinkequity","highestDevelopmentStatusID":"10","companyTruncated":"CEL-SCI \/ Thinkequity"},{"orgOrder":0,"company":"Acepodia","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"TAIWAN","productType":"Cell and Gene therapy","year":"2020","type":"Inapplicable","leadProduct":"ACE1702","moa":"||HER1\/HER2","graph1":"Oncology","graph2":"Phase I","graph3":"Acepodia","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Acepodia \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Acepodia \/ Inapplicable"},{"orgOrder":0,"company":"Genexine","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SOUTH KOREA","productType":"Protein","year":"2022","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"||IL-7 receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Genexine","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Genexine \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Genexine \/ Inapplicable"},{"orgOrder":0,"company":"Genexine","sponsor":"NeoImmuneTech","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SOUTH KOREA","productType":"Protein","year":"2020","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"||IL-7 receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Genexine","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Genexine \/ NeoImmuneTech","highestDevelopmentStatusID":"7","companyTruncated":"Genexine \/ NeoImmuneTech"},{"orgOrder":0,"company":"Aim ImmunoTech","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2023","type":"Inapplicable","leadProduct":"Rintatolimod","moa":"||Toll-like-3 receptor","graph1":"Oncology","graph2":"Phase II","graph3":"Aim ImmunoTech","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Aim ImmunoTech \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Aim ImmunoTech \/ Inapplicable"},{"orgOrder":0,"company":"G1 Therapeutics, Inc","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Trilaciclib","moa":"||CDK-4\/6","graph1":"Oncology","graph2":"Phase III","graph3":"G1 Therapeutics, Inc","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"G1 Therapeutics, Inc \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"G1 Therapeutics, Inc \/ Inapplicable"},{"orgOrder":0,"company":"IMV","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CANADA","productType":"Vaccine","year":"2022","type":"Inapplicable","leadProduct":"Maveropepimut-S","moa":"||T-cell receptor","graph1":"Oncology","graph2":"Phase II","graph3":"IMV","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"IMV \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"IMV \/ Inapplicable"},{"orgOrder":0,"company":"KSQ Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"||SOCS1","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"KSQ Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"KSQ Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"KSQ Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"BriaCell Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CANADA","productType":"Vaccine","year":"2025","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"||Undisclosed","graph1":"Oncology","graph2":"Phase II","graph3":"BriaCell Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intradermal Injection","sponsorNew":"BriaCell Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"BriaCell Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Lyell Immunopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"||CD19\/CD20","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Lyell Immunopharma","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous","sponsorNew":"Lyell Immunopharma \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Lyell Immunopharma \/ Inapplicable"},{"orgOrder":0,"company":"BriaCell Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CANADA","productType":"Cell and Gene therapy","year":"2025","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"||GM-CSF","graph1":"Oncology","graph2":"Phase III","graph3":"BriaCell Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intradermal Injection","sponsorNew":"BriaCell Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"BriaCell Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"CEL-SCI","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"Cisplatin","moa":"||CD4\/8","graph1":"Oncology","graph2":"Phase III","graph3":"CEL-SCI","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Peritumoral Injection","sponsorNew":"CEL-SCI \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"CEL-SCI \/ Inapplicable"},{"orgOrder":0,"company":"Takeda Pharmaceutical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Antibody-drug Conjugate","year":"2025","type":"Inapplicable","leadProduct":"Brentuximab Vedotin","moa":"||CD30","graph1":"Oncology","graph2":"Approved FDF","graph3":"Takeda Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Takeda Pharmaceutical \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Takeda Pharmaceutical \/ Inapplicable"},{"orgOrder":0,"company":"Lyell Immunopharma","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Private Placement","leadProduct":"Cyclophosphamide","moa":"||CD19\/CD20","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Lyell Immunopharma","amount2":0.10000000000000001,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.10000000000000001,"dosageForm":"Intravenous","sponsorNew":"Lyell Immunopharma \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Lyell Immunopharma \/ Undisclosed"}]

    Find Clinical Drug Pipeline Developments & Deals for Ciclophosphamide

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                            01

                            AbbVie Inc

                            U.S.A
                            AGGSpend
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                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Epcoritamab,Cyclophosphamide,Rituximab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Two Data Analyses Show Epcoritamab Induces Durable Complete Responses

                            Details : Tepkinly (epcoritamab) is an IgG1-bispecific antibody, which is evaluated for the treatment of diffuse large B-cell lymphoma. It is designed to direct cytotoxic T cells selectively.

                            Product Name : Tepkinly

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 09, 2024

                            Lead Product(s) : Epcoritamab,Cyclophosphamide,Rituximab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            NanoAlvand

                            Iran
                            CPhI WW Frankfurt
                            Attending
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Cyclophosphamide

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Endoxyna®; A Crucial Medication with A Novel Solution Formulation

                            Details : Endoxyna is a novel liquid formulation of cyclophosphamide, to replace the previous freeze-dried products. It is indicated for the treatment of cancer

                            Product Name : Endoxyna

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Inapplicable

                            June 29, 2024

                            Lead Product(s) : Cyclophosphamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            NanoAlvand

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                            03

                            Lyell Immunopharma

                            U.S.A arrow
                            AGGSpend
                            Not Confirmed

                            Lyell Immunopharma

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                            AGGSpend
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                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : LYL314,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : $100.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Lyell Immunopharma Announces up to $100 Million Equity Private Placement

                            Details : The proceeds from the placement will be used to fund the clinical development of LYL314, which is being evaluated for the treatment of Non-Hodgkin Lymphoma.

                            Product Name : LYL314

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 25, 2025

                            Lead Product(s) : LYL314,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : $100.0 million

                            Deal Type : Private Placement

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                            04

                            Takeda Pharmaceutical

                            Japan arrow
                            AGGSpend
                            Not Confirmed

                            Takeda Pharmaceutical

                            Japan arrow
                            AGGSpend
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Brentuximab Vedotin,Cyclophosphamide,Dacarbazine

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            European Commission Approves ADCETRIS® (brentuximab vedotin) in Combination with ECADD

                            Details : Adcetris (brentuximab vedotin) is a CD30 inhibitor, is now approved in combination with lenalidomide and rituximab for the treatment of Stage IIb/III/IV hodgkin lymphoma.

                            Product Name : Adcetris

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            June 03, 2025

                            Lead Product(s) : Brentuximab Vedotin,Cyclophosphamide,Dacarbazine

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            BriaCell Therapeutics

                            Canada arrow
                            AGGSpend
                            Not Confirmed

                            BriaCell Therapeutics

                            Canada arrow
                            AGGSpend
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : SV-BR-1-GM,Cyclophosphamide,Retifanlimab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            BriaCell Phase 2 Survival Data Beats Leading Standard in HR+ Breast Cancer

                            Details : Bria-IMT is a genetically engineered human breast cancer cell line with features of immune cells. It is being investigated with immune checkpoint inhibitor for treating breast cancer.

                            Product Name : Bria-IMT

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            April 16, 2025

                            Lead Product(s) : SV-BR-1-GM,Cyclophosphamide,Retifanlimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            KSQ Therapeutics

                            U.S.A arrow
                            AGGSpend
                            Not Confirmed

                            KSQ Therapeutics

                            U.S.A arrow
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                            Lead Product(s) : KSQ-004EX,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            KSQ Doses First Patient with CRISPR-Based KSQ-004EX eTIL Therapy

                            Details : KSQ-004EX, an eTIL cell therapy in which TIL are edited to inactivate the genes encoding SOCS1 and Regnase-1, is being evaluated for the treatment of advanced solid tumor.

                            Product Name : KSQ-004EX

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            April 09, 2025

                            Lead Product(s) : KSQ-004EX,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            CEL-SCI

                            U.S.A arrow
                            AGGSpend
                            Not Confirmed

                            CEL-SCI

                            U.S.A arrow
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                            Not Confirmed
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                            Lead Product(s) : Interleukin 2,Cisplatin,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Thinkequity

                            Deal Size : $2.5 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            CEL-SCI Announces Closing of $2.5 Million Offering

                            Details : The net proceeds from the offering will used to fund the development of Multikine (leukocyte interleukin) for treatment of patients suffering from stage III/IV squamous cell carcinoma of head & neck.

                            Product Name : Multikine

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            March 18, 2025

                            Lead Product(s) : Interleukin 2,Cisplatin,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Thinkequity

                            Deal Size : $2.5 million

                            Deal Type : Public Offering

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                            08

                            GC Cell

                            South Korea arrow
                            AGGSpend
                            Not Confirmed

                            GC Cell

                            South Korea arrow
                            AGGSpend
                            Not Confirmed
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                            Lead Product(s) : AB-205,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            GC Cell Doses First Patient in Phase 1 GCC2005 CD5 CAR-NK Therapy Trial

                            Details : GCC2005 (AB‑205) is a novel CD5 CAR‑NK cell therapy candidate, which is currently being evaluated for the treatment of T‑cell lymphoma.

                            Product Name : GCC2005

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            March 12, 2025

                            Lead Product(s) : AB-205,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            CEL-SCI

                            U.S.A arrow
                            AGGSpend
                            Not Confirmed

                            CEL-SCI

                            U.S.A arrow
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                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : Interleukin 2,Cyclophosphamide,Indomethacin

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CEL-SCI to Initiate Multikine Confirmatory Phase 3 Cancer Trial

                            Details : Multikine (leukocyte interleukin) is being evaluated for treatment of patients suffering from stage III/IV squamous cell carcinoma of head and neck.

                            Product Name : Multikine

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            February 20, 2025

                            Lead Product(s) : Interleukin 2,Cyclophosphamide,Indomethacin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            TC BioPharm

                            United Kingdom arrow
                            AGGSpend
                            Not Confirmed

                            TC BioPharm

                            United Kingdom arrow
                            AGGSpend
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                            Lead Product(s) : OmnImmune,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            TCBP Announces Successful Completion of Cohort A in the ACHIEVE Clinical Trial

                            Details : TCB008 (omnImmune) is an allogeneic unmodified cell therapy consisting activated and expanded gamma delta T cells. It is under trial for treatment of patients suffering from relapse/refractory AML.

                            Product Name : TCB008

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            February 13, 2025

                            Lead Product(s) : OmnImmune,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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