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    [{"orgOrder":0,"company":"Nexus Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Monoamine oxidase","graph1":"Hematology","graph2":"Approved FDF","graph3":"Nexus Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Nexus Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Nexus Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Nexus Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Monoamine oxidase","graph1":"Hematology","graph2":"Approved FDF","graph3":"Nexus Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Nexus Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Nexus Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"American Regent","sponsor":"Provepharm Life Solutions","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Monoamine oxidase","graph1":"Hematology","graph2":"Approved FDF","graph3":"American Regent","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"American Regent \/ Provepharm Life Solutions","highestDevelopmentStatusID":"15","companyTruncated":"American Regent \/ Provepharm Life Solutions"},{"orgOrder":0,"company":"Ondine Biomedical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CANADA","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Ondine Biomedical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Nasal Solution","sponsorNew":"Ondine Biomedical \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ondine Biomedical \/ Inapplicable"},{"orgOrder":0,"company":"Ondine Biomedical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CANADA","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"||Monoamine oxidase","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Ondine Biomedical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Nasal Solution","sponsorNew":"Ondine Biomedical \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ondine Biomedical \/ Inapplicable"},{"orgOrder":0,"company":"Ondine Biomedical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CANADA","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Ondine Biomedical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Ondine Biomedical \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Ondine Biomedical \/ Inapplicable"},{"orgOrder":0,"company":"Ondine Biomedical","sponsor":"Healthcare's Memorial Health University Medical Center","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CANADA","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"||Monoamine oxidase","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Ondine Biomedical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Topical Solution","sponsorNew":"Ondine Biomedical \/ Healthcare's Memorial Health University Medical Center","highestDevelopmentStatusID":"10","companyTruncated":"Ondine Biomedical \/ Healthcare's Memorial Health University Medical Center"}]

    Find Clinical Drug Pipeline Developments & Deals for CAS-61-73-4

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    CAS-61-73-4

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                            01

                            Nexus Pharmaceuticals

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                            Nexus Pharmaceuticals

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                            EPSC
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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nexus Pharmaceuticals Launches Methylene Blue Injection

                            Details : Methylene blue is a monoamine oxidase inhibitor, indicated for the treatment of methemoglobinemia.

                            Product Name : Methylene Blue-Generic

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 22, 2025

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Ondine Biomedical

                            Canada arrow
                            EPSC
                            Not Confirmed

                            Ondine Biomedical

                            Canada arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Methylene Blue,Chlorhexidine Gluconate

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Ondine Recruits First Patient for US Phase 3 Trial

                            Details : Nasal antimicrobial photodisinfection therapy consisiting of NF-031 (methylthioninium chloride & chlorhexidine gluconate) is being evaluated for treatment of surgical site infections.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 30, 2024

                            Lead Product(s) : Methylene Blue,Chlorhexidine Gluconate

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Nexus Pharmaceuticals

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Nexus Pharmaceuticals

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nexus Pharmaceuticals Receives FDA Approval for Methylene Blue Injection, USP

                            Details : The US FDA approved Methylene Blue Injection, USP (methylene blue). It is an oxidation-reduction agent that offers treatment of acquired methemoglobinemia.

                            Product Name : Methylene Blue Injection, USP

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 26, 2024

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Ondine Biomedical

                            Canada arrow
                            EPSC
                            Not Confirmed

                            Ondine Biomedical

                            Canada arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 25, 2024

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Ondine Biomedical

                            Canada arrow
                            EPSC
                            Not Confirmed

                            Ondine Biomedical

                            Canada arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Methylene Blue,Chlorhexidine Gluconate

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Healthcare's Memorial Health University Medical Center

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Ondine Biomedical Completes Patient Recruitment for US Phase II Nasal Photodisinfection Trial

                            Details : Photodynamic Antimicrobial Chemotherapy (PACT) using methylene blue is a potential antimicrobial therapy that combines light and a photosensitizing drug, promoting a phototoxic effect on the treated cells increases membrane permeability in Candida albica...

                            Product Name : PACT

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 08, 2022

                            Lead Product(s) : Methylene Blue,Chlorhexidine Gluconate

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Healthcare's Memorial Health University Medical Center

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            American Regent

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            American Regent

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                            EPSC
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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Study Phase : Approved FDF

                            Sponsor : Provepharm Life Solutions

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            American Regent Launches a New Vial Presentation

                            Details : ProvayBlue (methylene blue) is hypotonic and may be diluted before use in a solution of 50 mL 5% Dextrose Injection in order to avoid local pain, particularly in the pediatric population. Use the diluted solution immediately after preparation.

                            Product Name : ProvayBlue

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 30, 2022

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved FDF

                            Sponsor : Provepharm Life Solutions

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Ondine Biomedical

                            Canada arrow
                            EPSC
                            Not Confirmed

                            Ondine Biomedical

                            Canada arrow
                            EPSC
                            Not Confirmed
                            • fda
                            • EDQM
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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nasal Photodisinfection in All Patients Presenting for Surgery for a Wide Range of Surgical Procedures

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 25, 2021

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Wen-zhao ZHONG

                            Country arrow
                            EPSC
                            Not Confirmed

                            Wen-zhao ZHONG

                            Country arrow
                            EPSC
                            Not Confirmed
                            • fda
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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Undisclosed

                            Sponsor : Zhuhai Seine Technology Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            3D Printing for Nodule Localization

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 14, 2019

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Undisclosed

                            Sponsor : Zhuhai Seine Technology Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Chinese Academy of Sciences

                            Country arrow
                            EPSC
                            Not Confirmed

                            Chinese Academy of Sciences

                            Country arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Oncology

                            Study Phase : Undisclosed

                            Sponsor : Beijing Digital Precision Medicine | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Beijing Friendship Hospital | Tangshan People's Hospital | The Second Hospital of Hebei Medical University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sentinel Lymph Node Biopsy in Breast Cancer Surgery Using ICG

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 09, 2018

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Oncology

                            Highest Development Status : Undisclosed

                            Sponsor : Beijing Digital Precision Medicine | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Beijing Friendship Hospital | Tangshan People's Hospital | The Second Hospital of Hebei Medical University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Provepharm Life Solutions

                            France arrow
                            EPSC
                            Not Confirmed

                            Provepharm Life Solutions

                            France arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Study Phase : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MEthylene Blue In Patients With Acquired Methemoglobinemia

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 10, 2018

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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