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    [{"orgOrder":0,"company":"Chinese Academy of Sciences","sponsor":"Beijing Digital Precision Medicine | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Beijing Friendship Hospital | Tangshan People's Hospital | The Second Hospital of Hebei Medical University","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Oncology","graph2":"Undisclosed","graph3":"Chinese Academy of Sciences","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Chinese Academy of Sciences \/ Beijing Digital Precision Medicine | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Beijing Friendship Hospital | Tangshan People's Hospital | The Second Hospital of Hebei Medical University","highestDevelopmentStatusID":"1","companyTruncated":"Chinese Academy of Sciences \/ Beijing Digital Precision Medicine | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Beijing Friendship Hospital | Tangshan People's Hospital | The Second Hospital of Hebei Medical University"},{"orgOrder":0,"company":"Cosmo Technologies","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Miscellaneous","year":"2012","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Oncology","graph2":"Phase III","graph3":"Cosmo Technologies","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Cosmo Technologies \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cosmo Technologies \/ Undisclosed"},{"orgOrder":0,"company":"Cosmo Technologies","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Miscellaneous","year":"2014","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Oncology","graph2":"Phase III","graph3":"Cosmo Technologies","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Cosmo Technologies \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cosmo Technologies \/ Undisclosed"},{"orgOrder":0,"company":"Cosmo Technologies","sponsor":"Cross Research S.A.","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"UNITED KINGDOM","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Undisclosed","graph2":"Phase II","graph3":"Cosmo Technologies","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Cosmo Technologies \/ Cross Research S.A.","highestDevelopmentStatusID":"8","companyTruncated":"Cosmo Technologies \/ Cross Research S.A."},{"orgOrder":0,"company":"Provepharm Life Solutions","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"FRANCE","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Hematology","graph2":"Phase IV","graph3":"Provepharm Life Solutions","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Provepharm Life Solutions \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"Provepharm Life Solutions \/ Undisclosed"},{"orgOrder":0,"company":"Thomas Jefferson University","sponsor":"Teleflex Medical","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Miscellaneous","year":"2011","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Undisclosed","graph2":"Phase IV","graph3":"Thomas Jefferson University","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Catheter","sponsorNew":"Thomas Jefferson University \/ Teleflex Medical","highestDevelopmentStatusID":"11","companyTruncated":"Thomas Jefferson University \/ Teleflex Medical"},{"orgOrder":0,"company":"Nexus Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Hematology","graph2":"Approved FDF","graph3":"Nexus Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Nexus Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Nexus Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Nexus Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Hematology","graph2":"Approved FDF","graph3":"Nexus Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Nexus Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Nexus Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"American Regent","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Miscellaneous","year":"2015","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Hematology","graph2":"Approved FDF","graph3":"American Regent","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Injection","sponsorNew":"American Regent \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"American Regent \/ Undisclosed"},{"orgOrder":0,"company":"American Regent","sponsor":"Provepharm Life Solutions","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Hematology","graph2":"Approved FDF","graph3":"American Regent","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Injection","sponsorNew":"American Regent \/ Provepharm Life Solutions","highestDevelopmentStatusID":"15","companyTruncated":"American Regent \/ Provepharm Life Solutions"},{"orgOrder":0,"company":"Ondine Biomedical","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CANADA","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Ondine Biomedical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Solution","sponsorNew":"Ondine Biomedical \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Ondine Biomedical \/ Undisclosed"},{"orgOrder":0,"company":"Ondine Biomedical","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CANADA","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"||Guanylate cyclase (GC)","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Ondine Biomedical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Solution","sponsorNew":"Ondine Biomedical \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Ondine Biomedical \/ Undisclosed"},{"orgOrder":0,"company":"Ondine Biomedical","sponsor":"Healthcare's Memorial Health University Medical Center","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CANADA","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"||Guanylate cyclase (GC)","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Ondine Biomedical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Solution","sponsorNew":"Ondine Biomedical \/ Healthcare's Memorial Health University Medical Center","highestDevelopmentStatusID":"10","companyTruncated":"Ondine Biomedical \/ Healthcare's Memorial Health University Medical Center"},{"orgOrder":0,"company":"Ondine Biomedical","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CANADA","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Ondine Biomedical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Ondine Biomedical \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Ondine Biomedical \/ Undisclosed"},{"orgOrder":0,"company":"Medtronic Plc","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Miscellaneous","year":"2012","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Undisclosed","graph2":"Undisclosed","graph3":"Medtronic Plc","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Medtronic Plc \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Medtronic Plc \/ Undisclosed"},{"orgOrder":0,"company":"Wen-zhao ZHONG","sponsor":"Zhuhai Seine Technology Co., Ltd","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"","productType":"Miscellaneous","year":"2019","type":"Inapplicable","leadProduct":"Methylene Blue","moa":"Guanylate cyclase (GC)","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Undisclosed","graph3":"Wen-zhao ZHONG","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Wen-zhao ZHONG \/ Zhuhai Seine Technology Co., Ltd","highestDevelopmentStatusID":"1","companyTruncated":"Wen-zhao ZHONG \/ Zhuhai Seine Technology Co., Ltd"}]

    Find Clinical Drug Pipeline Developments & Deals for azul de metileno

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                            01

                            Nexus Pharmaceuticals

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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nexus Pharmaceuticals Launches Methylene Blue Injection

                            Details : Methylene blue is a monoamine oxidase inhibitor, indicated for the treatment of methemoglobinemia.

                            Product Name : Methylene Blue-Generic

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 22, 2025

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Ondine Biomedical

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                            Ondine Biomedical

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                            Lead Product(s) : Methylene Blue,Chlorhexidine Gluconate

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Ondine Recruits First Patient for US Phase 3 Trial

                            Details : Nasal antimicrobial photodisinfection therapy consisiting of NF-031 (methylthioninium chloride & chlorhexidine gluconate) is being evaluated for treatment of surgical site infections.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 30, 2024

                            Lead Product(s) : Methylene Blue,Chlorhexidine Gluconate

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Nexus Pharmaceuticals

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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nexus Pharmaceuticals Receives FDA Approval for Methylene Blue Injection, USP

                            Details : The US FDA approved Methylene Blue Injection, USP (methylene blue). It is an oxidation-reduction agent that offers treatment of acquired methemoglobinemia.

                            Product Name : Methylene Blue Injection, USP

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 26, 2024

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Ondine Biomedical

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                            Ondine Biomedical

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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections

                            Details : Methylene Blue is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Surgical Wound Infection.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 25, 2024

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Ondine Biomedical

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                            Ondine Biomedical

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                            Lead Product(s) : Methylene Blue,Chlorhexidine Gluconate

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Healthcare's Memorial Health University Medical Center

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Ondine Biomedical Completes Patient Recruitment for US Phase II Nasal Photodisinfection Trial

                            Details : Photodynamic Antimicrobial Chemotherapy (PACT) using methylene blue is a potential antimicrobial therapy that combines light and a photosensitizing drug, promoting a phototoxic effect on the treated cells increases membrane permeability in Candida albica...

                            Product Name : PACT

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 08, 2022

                            Lead Product(s) : Methylene Blue,Chlorhexidine Gluconate

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Healthcare's Memorial Health University Medical Center

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            American Regent

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                            American Regent

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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Study Phase : Approved FDF

                            Sponsor : Provepharm Life Solutions

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            American Regent Launches a New Vial Presentation

                            Details : ProvayBlue (methylene blue) is hypotonic and may be diluted before use in a solution of 50 mL 5% Dextrose Injection in order to avoid local pain, particularly in the pediatric population. Use the diluted solution immediately after preparation.

                            Product Name : ProvayBlue

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            June 30, 2022

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved FDF

                            Sponsor : Provepharm Life Solutions

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Ondine Biomedical

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                            Ondine Biomedical

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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nasal Photodisinfection in All Patients Presenting for Surgery for a Wide Range of Surgical Procedures

                            Details : Methylene Blue is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Surgical Wound Infection.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 25, 2021

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Wen-zhao ZHONG

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                            Wen-zhao ZHONG

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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Undisclosed

                            Sponsor : Zhuhai Seine Technology Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            3D Printing for Nodule Localization

                            Details : Methylene Blue is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Solitary Pulmonary Nodule.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 14, 2019

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Undisclosed

                            Sponsor : Zhuhai Seine Technology Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Chinese Academy of Sciences

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                            Chinese Academy of Sciences

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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Oncology

                            Study Phase : Undisclosed

                            Sponsor : Beijing Digital Precision Medicine | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Beijing Friendship Hospital | Tangshan People's Hospital | The Second Hospital of Hebei Medical University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sentinel Lymph Node Biopsy in Breast Cancer Surgery Using ICG

                            Details : Methylene Blue is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Breast Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 09, 2018

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Oncology

                            Highest Development Status : Undisclosed

                            Sponsor : Beijing Digital Precision Medicine | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Beijing Friendship Hospital | Tangshan People's Hospital | The Second Hospital of Hebei Medical University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Provepharm Life Solutions

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                            Provepharm Life Solutions

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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Study Phase : Phase IV

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MEthylene Blue In Patients With Acquired Methemoglobinemia

                            Details : Methylene Blue is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Methemoglobinemia.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 10, 2018

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase IV

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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