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Find Clinical Drug Pipeline Developments & Deals by Aragen Life Sciences
Under the collaboration, Aragen will deploy its proven experimental integrated drug discovery (IDD) platform to help FAR advance its small molecule program towards an important milestone in neurodegeneration.
Xentuzumab* (BI 836845) is a humanized immunoglobulin G (IgG) 1 monoclonal antibody (mAb) that targets insulin-like growth factor (IGF) ligands IGF-1 and IGF-2 for treatment of breast cancer.
The aim of this partnership is to identify the uPRIT with the optimal urokinase plasminogen activator receptor binding profile, enabling selective delivery of a cytotoxic radioisotope to just those aberrantly activated immune cells that produce the cytokine storm.
Under the terms of the collaboration, Aragen is set to provide Serum with high expressing cell lines enabling Serum to quickly move their RapTr™ platform forward into Manufacturing.