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Morgan","pharmaFlowCategory":"D","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"U.S.A","productType":"Protein","year":"2022","type":"Public Offering","leadProduct":"Efruxifermin","moa":"growth factors: fibroblast growth factors; Fc fusion protein","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase III","graph3":"Akero Therapeutics","amount2":0.20000000000000001,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hepatology","amount2New":0.37,"dosageForm":"Injection","sponsorNew":"Akero Therapeutics \/ J.P. Morgan","highestDevelopmentStatusID":"10","companyTruncated":"Akero Therapeutics \/ J.P. Morgan"},{"orgOrder":0,"company":"Akero Therapeutics","sponsor":"Pfizer Inc","pharmaFlowCategory":"D","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"U.S.A","productType":"Protein","year":"2022","type":"Financing","leadProduct":"Efruxifermin","moa":"growth factors: fibroblast growth factors; Fc fusion protein","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase III","graph3":"Akero Therapeutics","amount2":0.029999999999999999,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hepatology","amount2New":0.029999999999999999,"dosageForm":"Injection","sponsorNew":"Akero Therapeutics \/ Pfizer Inc","highestDevelopmentStatusID":"10","companyTruncated":"Akero Therapeutics \/ Pfizer Inc"},{"orgOrder":0,"company":"Akero Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"U.S.A","productType":"Protein","year":"2020","type":"Inapplicable","leadProduct":"Efruxifermin","moa":"growth factors: fibroblast growth factors; Fc fusion protein","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase III","graph3":"Akero Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Akero Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Akero Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Akero Therapeutics","sponsor":"Novo Nordisk","pharmaFlowCategory":"D","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"U.S.A","productType":"Protein","year":"2025","type":"Acquisition","leadProduct":"Efruxifermin","moa":"GPCR","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase III","graph3":"Akero Therapeutics","amount2":5.2000000000000002,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hepatology","amount2New":5.2000000000000002,"dosageForm":"Injection","sponsorNew":"Akero Therapeutics \/ Novo Nordisk","highestDevelopmentStatusID":"10","companyTruncated":"Akero Therapeutics \/ Novo Nordisk"}]

Find Clinical Drug Pipeline Developments & Deals by Akero Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          BOS Manchester
                          Not Confirmed
                          BOS Manchester
                          Not Confirmed

                          Details : Through the acquisition, Novo will leverage Akero pipeline which includes Efruxifermin, a protein targeting growth factors, for the treatment of MASH.

                          Product Name : EFX

                          Product Type : Protein

                          Upfront Cash : $5,200.0 million

                          October 09, 2025

                          Lead Product(s) : Efruxifermin

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase III

                          Sponsor : Novo Nordisk

                          Deal Size : $5,200.0 million

                          Deal Type : Acquisition

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                          02

                          BOS Manchester
                          Not Confirmed
                          BOS Manchester
                          Not Confirmed

                          Details : The net proceeds will be used to advance the clinical development of lead product EFX (efruxifermin). It is being evaluated for the treatment of compensated cirrhosis due to MASH.

                          Product Name : EFX

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          January 30, 2025

                          Lead Product(s) : Efruxifermin

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase III

                          Sponsor : J.P. Morgan

                          Deal Size : $402.0 million

                          Deal Type : Public Offering

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                          03

                          BOS Manchester
                          Not Confirmed
                          BOS Manchester
                          Not Confirmed

                          Details : The net proceeds will be to advance the clinical development of lead product EFX (efruxifermin). It is being evaluated for the treatment of compensated cirrhosis due to MASH.

                          Product Name : EFX

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          January 28, 2025

                          Lead Product(s) : Efruxifermin

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase III

                          Sponsor : J.P. Morgan

                          Deal Size : $350.0 million

                          Deal Type : Public Offering

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                          04

                          BOS Manchester
                          Not Confirmed
                          BOS Manchester
                          Not Confirmed

                          Details : EFX (efruxifermin) is a differentiated Fc-FGF21 fusion protein drug candidate, which is being evaluated for the treatment of patients with compensated cirrhosis (F4) due to MASH.

                          Product Name : EFX

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          January 27, 2025

                          Lead Product(s) : Efruxifermin

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          BOS Manchester
                          Not Confirmed
                          BOS Manchester
                          Not Confirmed

                          Details : The net proceeds will be to advance the clinical development of lead product EFX (efruxifermin). It is being evaluated for the treatment of compensated cirrhosis due to MASH.

                          Product Name : EFX

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          January 27, 2025

                          Lead Product(s) : Efruxifermin

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase III

                          Sponsor : J.P. Morgan

                          Deal Size : $300.0 million

                          Deal Type : Public Offering

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                          06

                          BOS Manchester
                          Not Confirmed
                          BOS Manchester
                          Not Confirmed

                          Details : EFX (efruxifermin) is a differentiated Fc-FGF21 fusion protein drug candidate, which is being evaluated for the treatment of patients with compensated cirrhosis (F4) due to MASH.

                          Product Name : EFX

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          January 24, 2025

                          Lead Product(s) : Efruxifermin

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          BOS Manchester
                          Not Confirmed
                          BOS Manchester
                          Not Confirmed

                          Details : EFX (efruxifermin) is a differentiated Fc-FGF21 fusion protein drug candidate, which is being evaluated for the treatment of patients with compensated cirrhosis (F4) due to MASH.

                          Product Name : EFX

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          January 13, 2025

                          Lead Product(s) : Efruxifermin

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          BOS Manchester
                          Not Confirmed
                          BOS Manchester
                          Not Confirmed

                          Details : EFX (efruxifermin) is a differentiated Fc-FGF21 fusion protein drug candidate, which is being evaluated for the treatment of patients with compensated cirrhosis (F4) due to MASH.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          September 09, 2024

                          Lead Product(s) : Efruxifermin

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          BOS Manchester
                          Not Confirmed
                          BOS Manchester
                          Not Confirmed

                          Details : Efruxifermin is a Protein drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Non-alcoholic Fatty Liver Disease.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          July 30, 2024

                          Lead Product(s) : Efruxifermin

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          BOS Manchester
                          Not Confirmed
                          BOS Manchester
                          Not Confirmed

                          Details : EFX (efruxifermin) is a differentiated Fc-FGF21 fusion protein drug candidate, which is being evaluated for the treatment of patients with compensated cirrhosis (F4) due to MASH.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          June 11, 2024

                          Lead Product(s) : Efruxifermin

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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