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Also known as: Sacubitril sodium, 149690-05-1, Ahu-377 sodium, Sacubitril (sodium), Mop72gep8z, Sodium;4-[[(2s,4r)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate
Molecular Formula
C24H28NNaO5
Molecular Weight
433.5  g/mol
InChI Key
RRTBVEJIZWGATF-JKSHRDEXSA-M
FDA UNII
MOP72GEP8Z

Sacubitril Sodium
1 2D Structure

Sacubitril Sodium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate
2.1.2 InChI
InChI=1S/C24H29NO5.Na/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19;/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28);/q;+1/p-1/t17-,21+;/m1./s1
2.1.3 InChI Key
RRTBVEJIZWGATF-JKSHRDEXSA-M
2.1.4 Canonical SMILES
CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)[O-].[Na+]
2.1.5 Isomeric SMILES
CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)[O-].[Na+]
2.2 Other Identifiers
2.2.1 UNII
MOP72GEP8Z
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Sacubitril Sodium

2. 149690-05-1

3. Ahu-377 Sodium

4. Sacubitril (sodium)

5. Mop72gep8z

6. Sodium;4-[[(2s,4r)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate

7. Unii-mop72gep8z

8. Sacubitril Sodium Salt

9. Sacubitril Sodium [mi]

10. Schembl21239956

11. Dtxsid90164362

12. Hy-15407b

13. (1,1'-biphenyl)-4-pentanoic Acid, Gamma-((3-carboxy-1-oxopropyl)amino)-alpha-methyl-, 4-ethyl Ester, Sodium Salt (1:1), (alphar,gammas)-

14. Cs-0079358

15. A937423

16. Q27284149

17. (1,1'-biphenyl)-4-pentanoic Acid, .gamma.-((3-carboxy-1-oxopropyl)amino)-.alpha.-methyl-, 4-ethyl Ester, Sodium Salt (1:1), (.alpha.r,.gamma.s)-

18. Sodium 4-(((2s,4r)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 433.5 g/mol
Molecular Formula C24H28NNaO5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count12
Exact Mass433.18651728 g/mol
Monoisotopic Mass433.18651728 g/mol
Topological Polar Surface Area95.5 Ų
Heavy Atom Count31
Formal Charge0
Complexity556
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2

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DT. 03\/09\/2024 RETEST DT. 02\/","address":"PLOT NO.5222, PHASE- IV,","city":"AHMEDABAD -","supplier":"ZHEJIANG TIANYU PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"UNISON PHARMACEUTICALS PRIVATE LTD","customerCountry":"INDIA","quantity":"37.00","actualQuantity":"37","unit":"KGS","unitRateFc":"650","totalValueFC":"24210.1","currency":"USD","unitRateINR":"55217.5","date":"07-Nov-2024","totalValueINR":"2043047.5","totalValueInUsd":"24210.1","indian_port":"Ahmedabad Air","hs_no":"29339990","bill_no":"6548861","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Crystalline","supplierPort":"SHANGHAI","supplierAddress":"JIANGKOU DEVELOPMENT ZONE HUANGYAN TAIZHOU ZHEJIANG, CHINA SDNF CHINA","customerAddress":"PLOT NO.5222, PHASE- IV,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1736274600,"product":"SACUBITRIL CALCIUM 20","address":"7.1.77\/E\/1\/303, DHARAM KARAM ROAD","city":"HYDERABAD,A.P.","supplier":"ZHEJIANG RAYBOW PHARMACEUTICAL COLTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"DIVIS LABORATORIES LTD","customerCountry":"INDIA","quantity":"5247.66","actualQuantity":"5247.66","unit":"KGS","unitRateFc":"529.3","totalValueFC":"2789530.6","currency":"USD","unitRateINR":"45837.4","date":"08-Jan-2025","totalValueINR":"240538985.53","totalValueInUsd":"2789530.6","indian_port":"Vizag-DLL SEZ","hs_no":"29339990","bill_no":"7674474","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO.18 NANYANGSAN ROAD ,DUQIAO LINHAI NANYANG SAN RD,TAIZHOU CITY SDNF China","customerAddress":"7.1.77\/E\/1\/303, DHARAM KARAM ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1739557800,"product":"SACUBITRIL SODIUM SACUBITRIL ISODIUM","address":"#28 CANTON ROWS, PETBASHEERBAD","city":"HYDERABAD","supplier":"ZHEJIANG TIANYU PHARMACEUTICAL COLTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"AIZANT DRUG RESEARCH SOLUTIONS PRIVATE LTD","customerCountry":"INDIA","quantity":"831.00","actualQuantity":"831","unit":"KGS","unitRateFc":"1950","totalValueFC":"1647206.2","currency":"USD","unitRateINR":"172380","date":"15-Feb-2025","totalValueINR":"143247780","totalValueInUsd":"1647206.2","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"8384004","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"Jiangkou Development Zone Huangyan Taizhou Zhejiang China CN","customerAddress":"#28 CANTON ROWS, PETBASHEERBAD"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1740335400,"product":"SACUBITRIL CALCIUM 20","address":"7.1.77\/E\/1\/303, DHARAM KARAM ROAD","city":"HYDERABAD,A.P.","supplier":"ZHEJIANG RAYBOW PHARMACEUTICAL COLTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"DIVIS LABORATORIES LTD","customerCountry":"INDIA","quantity":"5243.27","actualQuantity":"5243.27","unit":"KGS","unitRateFc":"529.3","totalValueFC":"2800343.6","currency":"USD","unitRateINR":"46446.1","date":"24-Feb-2025","totalValueINR":"243529311.67","totalValueInUsd":"2800343.6","indian_port":"Vizag-DLL SEZ","hs_no":"29339990","bill_no":"8530105","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO.18 NANYANGSAN ROAD ,DUQIAO LINHAI NANYANG SAN ROAD,TAIZHOU CIT SDNF China","customerAddress":"7.1.77\/E\/1\/303, DHARAM KARAM ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1745001000,"product":"SACUBITRIL SODIUM SACUBITRIL SODIUM","address":"802, BLOCK-A, ALPINE HEIGHTS","city":"HYDERABAD, A.P.","supplier":"ZHUHAI RUNDU PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"AHUHAI","customer":"AET LABORATORIES PRIVATE LTD","customerCountry":"INDIA","quantity":"605.00","actualQuantity":"605","unit":"KGS","unitRateFc":"800","totalValueFC":"488513.2","currency":"USD","unitRateINR":"69120","date":"19-Apr-2025","totalValueINR":"41817600","totalValueInUsd":"488513.2","indian_port":"Hyderabad Air","hs_no":"29173990","bill_no":"9590093","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"AHUHAI","supplierAddress":"NO.6,AIRPORT NORTH ROAD,SANZAO TOWN JINWAN DISTRICT,ZHUHAI GUANGDONG P.R. CHINA CN","customerAddress":"802, BLOCK-A, ALPINE HEIGHTS"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1745001000,"product":"SACUBITRIL SODIUM SACUBITRIL SODIUM","address":"2ND FLOOR, SERENE CHAMBERS,,ROAD N","city":"HYDEABAD,TELANGANA","supplier":"KRKA DD NOVO MESTO","supplierCountry":"SLOVENIA","foreign_port":"LJUBLJANA - BRNIK","customer":"LAURUS LABS LTD","customerCountry":"INDIA","quantity":"2.05","actualQuantity":"2.05","unit":"KGS","unitRateFc":"4497.5","totalValueFC":"9305.8","currency":"EURO","unitRateINR":"388583.3","date":"19-Apr-2025","totalValueINR":"796595.76","totalValueInUsd":"9305.8","indian_port":"Hyderabad Air","hs_no":"29242990","bill_no":"9590958","productDescription":"API","marketType":"REGULATED MARKET","country":"SLOVENIA","selfForZScoreResived":"Pharma Grade","supplierPort":"LJUBLJANA - BRNIK","supplierAddress":"SMARJESKA CESTA 6, NOVO MESTO NOVO MESTO 8501 SDNF Slovenia","customerAddress":"2ND FLOOR, SERENE CHAMBERS,,ROAD N"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1746642600,"product":"SACUBITRIL SODIUM SACUBITRIL SODIUM","address":"107A,VINAY BHAVYA COMPLEX","city":"MUMBAI ,MAHARASHTRA","supplier":"ZHEJIANG TIANYU PHARMACEUTICAL COLTD","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"HARMAN FINOCHEM LTD","customerCountry":"INDIA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"650","totalValueFC":"1958","currency":"USD","unitRateINR":"55607.5","date":"08-May-2025","totalValueINR":"166822.5","totalValueInUsd":"1958","indian_port":"Bombay Air","hs_no":"29339990","bill_no":"9944596","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"JIANGKOU DEVELOPMENT ZONE HUANGYAN, TAIZHOU ZHEJIANG, CHINA CN","customerAddress":"107A,VINAY BHAVYA COMPLEX"}]
28-Feb-2022
30-Jun-2025
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ABOUT THIS PAGE

Looking for 149690-05-1 / Sacubitril Sodium API manufacturers, exporters & distributors?

Sacubitril Sodium manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Sacubitril Sodium API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Sacubitril Sodium manufacturer or Sacubitril Sodium supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Sacubitril Sodium manufacturer or Sacubitril Sodium supplier.

PharmaCompass also assists you with knowing the Sacubitril Sodium API Price utilized in the formulation of products. Sacubitril Sodium API Price is not always fixed or binding as the Sacubitril Sodium Price is obtained through a variety of data sources. The Sacubitril Sodium Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Sacubitril Sodium

Synonyms

149690-05-1, Ahu-377 sodium, Sacubitril (sodium), Mop72gep8z, Sodium;4-[[(2s,4r)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate, Unii-mop72gep8z

Cas Number

149690-05-1

Unique Ingredient Identifier (UNII)

MOP72GEP8Z

Sacubitril Sodium Manufacturers

A Sacubitril Sodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sacubitril Sodium, including repackagers and relabelers. The FDA regulates Sacubitril Sodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sacubitril Sodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Sacubitril Sodium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Sacubitril Sodium Suppliers

A Sacubitril Sodium supplier is an individual or a company that provides Sacubitril Sodium active pharmaceutical ingredient (API) or Sacubitril Sodium finished formulations upon request. The Sacubitril Sodium suppliers may include Sacubitril Sodium API manufacturers, exporters, distributors and traders.

click here to find a list of Sacubitril Sodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sacubitril Sodium USDMF

A Sacubitril Sodium DMF (Drug Master File) is a document detailing the whole manufacturing process of Sacubitril Sodium active pharmaceutical ingredient (API) in detail. Different forms of Sacubitril Sodium DMFs exist exist since differing nations have different regulations, such as Sacubitril Sodium USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Sacubitril Sodium DMF submitted to regulatory agencies in the US is known as a USDMF. Sacubitril Sodium USDMF includes data on Sacubitril Sodium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Sacubitril Sodium USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Sacubitril Sodium suppliers with USDMF on PharmaCompass.

Sacubitril Sodium WC

A Sacubitril Sodium written confirmation (Sacubitril Sodium WC) is an official document issued by a regulatory agency to a Sacubitril Sodium manufacturer, verifying that the manufacturing facility of a Sacubitril Sodium active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Sacubitril Sodium APIs or Sacubitril Sodium finished pharmaceutical products to another nation, regulatory agencies frequently require a Sacubitril Sodium WC (written confirmation) as part of the regulatory process.

click here to find a list of Sacubitril Sodium suppliers with Written Confirmation (WC) on PharmaCompass.

Sacubitril Sodium NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Sacubitril Sodium as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Sacubitril Sodium API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Sacubitril Sodium as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Sacubitril Sodium and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Sacubitril Sodium NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Sacubitril Sodium suppliers with NDC on PharmaCompass.

Sacubitril Sodium GMP

Sacubitril Sodium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sacubitril Sodium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sacubitril Sodium GMP manufacturer or Sacubitril Sodium GMP API supplier for your needs.

Sacubitril Sodium CoA

A Sacubitril Sodium CoA (Certificate of Analysis) is a formal document that attests to Sacubitril Sodium's compliance with Sacubitril Sodium specifications and serves as a tool for batch-level quality control.

Sacubitril Sodium CoA mostly includes findings from lab analyses of a specific batch. For each Sacubitril Sodium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sacubitril Sodium may be tested according to a variety of international standards, such as European Pharmacopoeia (Sacubitril Sodium EP), Sacubitril Sodium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sacubitril Sodium USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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