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    Also known as: 57-00-1, N-amidinosarcosine, Creatin, Kreatin, Krebiozon, N-methyl-n-guanylglycine
    Molecular Formula
    C4H9N3O2
    Molecular Weight
    131.13  g/mol
    InChI Key
    CVSVTCORWBXHQV-UHFFFAOYSA-N
    FDA UNII
    MU72812GK0
    Creatine
    An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine.
    1 2D Structure

    Creatine

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-[carbamimidoyl(methyl)amino]acetic acid
    2.1.2 InChI
    InChI=1S/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H3,5,6)(H,8,9)
    2.1.3 InChI Key
    CVSVTCORWBXHQV-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CN(CC(=O)O)C(=N)N
    2.2 Other Identifiers
    2.2.1 UNII
    MU72812GK0
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 57-00-1

    2. N-amidinosarcosine

    3. Creatin

    4. Kreatin

    5. Krebiozon

    6. N-methyl-n-guanylglycine

    7. 2-(1-methylguanidino)acetic Acid

    8. Methylglycocyamine

    9. Glycine, N-(aminoiminomethyl)-n-methyl-

    10. (alpha-methylguanido)acetic Acid

    11. Creatine, Hydrate

    12. Pyrolysate

    13. N-carbamimidoyl-n-methylglycine

    14. Methylguanidoacetic Acid

    15. Cosmocair C 100

    16. 2-(1-methylcarbamimidamido)acetic Acid

    17. Creatine, Anhydrous

    18. Kreatinum

    19. Neotine

    20. Alpha-methylguanidino Acetic Acid

    21. 2-[carbamimidoyl(methyl)amino]acetic Acid

    22. N-(aminoiminomethyl)-n-methylglycine

    23. (.alpha.-methylguanido)acetic Acid

    24. Nsc 8752

    25. Nsc-8752

    26. N-[(e)-amino(imino)methyl]-n-methylglycine

    27. Ai3-15320

    28. Chebi:16919

    29. ((amino(imino)methyl)(methyl)amino)acetic Acid

    30. Nsc8752

    31. Mu72812gk0

    32. (n-methylcarbamimidamido)acetic Acid

    33. N-(aminoiminomethyl)-n-methyl-glycine

    34. Creatine (8ci)

    35. ((amino(imino)methyl)(methyl)amino)acetate

    36. [[amino(imino)methyl](methyl)amino]acetate

    37. [[amino(imino)methyl](methyl)amino]acetic Acid

    38. Unii-mu72812gk0

    39. A-meethyl Guanidine Acetic Acid

    40. Hsdb 7336

    41. Methylguanidoacetate

    42. Iom

    43. Einecs 200-306-6

    44. Mfcd00004282

    45. Creatine [hsdb]

    46. Creatine [inci]

    47. Creatine [ii]

    48. Creatine [mi]

    49. Creatine [vandf]

    50. Bmse000078

    51. Bmse000950

    52. Bmse000999

    53. Creatine [usp-rs]

    54. Creatine [who-dd]

    55. Ec 200-306-6

    56. (alpha-methylguanido)acetate

    57. (a-methylguanido)acetic Acid

    58. Schembl21567

    59. Creatine, Hydrate (salt/mix)

    60. Chembl283800

    61. Gtpl4496

    62. Dtxsid1040451

    63. Str05570

    64. Zinc3861770

    65. Bbl012187

    66. Bdbm50357229

    67. S5588

    68. Stl163516

    69. Akos005717096

    70. 2-(n-methylcarbamimidamido)acetic Acid

    71. Ccg-266112

    72. Cs-w011104

    73. Db00148

    74. Hy-w010388

    75. N-[amino(imino)methyl]-n-methylglycine

    76. Creatine, Anhydrous, >=99.0% (nt)

    77. 2-(carbamimidoyl-methyl-amino)acetic Acid

    78. Ac-34370

    79. C3610

    80. Ft-0624083

    81. (n-(amidino)-n-methylamino)acetic Acid

    82. C00300

    83. D89574

    84. [[amino(imino)methyl](methyl)amino]acetic Acid #

    85. Q223600

    86. W-105270

    87. F8880-7830

    88. 1093737-19-9

    2.4 Create Date
    2004-09-16
    3 Chemical and Physical Properties
    Molecular Weight 131.13 g/mol
    Molecular Formula C4H9N3O2
    XLogP3-1.2
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count3
    Exact Mass131.069476538 g/mol
    Monoisotopic Mass131.069476538 g/mol
    Topological Polar Surface Area90.4 Ų
    Heavy Atom Count9
    Formal Charge0
    Complexity134
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Therapeutic Uses

    Creatine, as well as a creatine analogue called cyclocreatine, inhibit growth of a broad range of solid tumors in rat models of cancer; these tumors express high levels of CK. Although the mechanism for tumor inhibition is unknown...

    Medical Economics Co; Physicians Desk Reference for Nutritional Supplements 1st ed p.115 (2001)

    4.2 Drug Warning

    Phosphocreatine inhibits enzymes in the glycolitic pathway, including glyceraldehydes-3-phosphate dehydrogenase, phosphofructokinase and pyruvate kinase.

    Medical Economics Co; Physicians Desk Reference for Nutritional Supplements 1st ed p.115 (2001)

    Safety data are lacking and are urgently needed, especially for long-term use of creatine and for use among the pediatric population (including adolescence) and among those in poor health. There are some reports that long-term use of creatine may be nephrotoxic. This needs further investigation before long-term creatine supplementation can be recommended under any circumstance.

    Medical Economics Co; Physicians Desk Reference for Nutritional Supplements 1st ed p.116 (2001)

    Creatine is contraindicated in those with renal failure and renal disorders such as nephritic syndrome.

    Medical Economics Co; Physicians Desk Reference for Nutritional Supplements 1st ed p.116 (2001)

    Anecdotal reports of adverse events to FDA have included rash, dyspnea, vomiting, diarrhea, nervousness, anxiety, migraine, fatigue, polymyositis, myopathy,seizures and atrial fibrillation.

    Medical Economics Co; Physicians Desk Reference for Nutritional Supplements 1st ed p.117 (2001)

    There are reports of elevated serum creatinine, a metabolite of creatine and a marker of kidney function, in some who take creatine and have normal renal function. This /effect on renal function tests/ is reversible upon discontinuation of creatine.

    Medical Economics Co; Physicians Desk Reference for Nutritional Supplements 1st ed p.115 (2001)

    4.3 Drug Indication

    For nutritional supplementation, also for treating dietary shortage or imbalance.

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Creatine is a essential, non-proteinaceous amino acid derivative found in all animals. It is synthesized in the kidney, liver, and pancreas from L-arginine, glycine and L-methionine. Following its biosynthesis, creatine is transported to the skeletal muscle, heart, brain and other tissues. Most of the creatine is metabolized in these tissues to phosphocreatine (creatine phosphate). Phosphocreatine is a major energy storage form in the body. Supplemental creatine may have an energy-generating action during anaerobic exercise and may also have neuroprotective and cardioprotective actions.

    5.2 Absorption, Distribution and Excretion

    In muscle and nerve, most of the creatine is phosphorylated to phosphocreatine (pCr) in a reaction that is catalyzed by the enezyme creatine kinase (CK), there are three isoforms of (isoenzymes) of CK. CK-MM is the skeletal muscle isoform; CK-BB, the brain isoform, and CK-MB, the isoform found in cardiac muscle. Most of the PCr in the body is in skeletal muscle.

    Medical Economics Co; Physicians Desk Reference for Nutritional Supplements 1st ed p.115 (2001)

    Creatine is absorbed from the small intestines and enters the portal circulation and is transported to the liver. The ingested creatine, and the creatine made in the liver, is then transported into the systemic circulation and distributed into various tissues of the body, including muscle and nerves, by crossing the cell membrane via a specific creatine-transported system against a 200:1 gradient.

    Medical Economics Co; Physicians Desk Reference for Nutritional Supplements 1st ed p.115 (2001)

    5.3 Metabolism/Metabolites

    Within muscle and nerve cells, about 60 to 67% of the creatine entering the cells gets converted to phosphocreatine via the enzyme creatine kinase. About 2% of creatine is converted to creatinine, and both creatine and creatinine are excreted by the kidneys.

    Medical Economics Co; Physicians Desk Reference for Nutritional Supplements 1st ed p.115 (2001)

    5.4 Biological Half-Life

    3 hours

    5.5 Mechanism of Action

    In the muscles, a fraction of the total creatine binds to phosphate - forming creatine phosphate. The reaction is catalysed by creatine kinase, and the result is phosphocreatine (PCr). Phosphocreatine binds with adenosine diphosphate to convert it back to ATP (adenosine triphosphate), an important cellular energy source for short term ATP needs prior to oxidative phosphorylation.

    Supplemental creatine may have an energy-generating action during anaerobic exercise and may also have neuroprotective and cardioprotective actions.

    Medical Economics Co; Physicians Desk Reference for Nutritional Supplements 1st ed p.115 (2001)

    Creatine, creatine kinase and phosphocreatine make up an intricate cellular enegy buffering and transport system connecting sites of energy production in the mitochondria with sites of energy consumption. CK is a key enzyme in involved in cellular energy homeostasis. It reversibly catalyzes the transfer of the high-energy phosphate bond in PCr to adenosine diphosphate (ADP) to form adenosine triphosphate (ATP), and it catalyzes the transfer of the high-energy phosphate bond in ATP to creatine to form PCr. During periods of intense exercise and skeletal muscle contraction, bioenergetic metabolism switches from one in which oxidative phosphorylation is the major pathway of ATP production to one in which so-called anaerobic glycolysis becomes dominant.

    Medical Economics Co; Physicians Desk Reference for Nutritional Supplements 1st ed p.115 (2001)

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    Jing Jing Pharmaceutical

    China

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    Jing Jing Pharmaceutical

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    Creatine

    About the Company : Jing Jing Pharmaceutical Co., Ltd., founded in October 2007, covers an area of 200 mu, registered capital of 257.28 million yuan, and employees of more than 700 people, is a high-t...

    Jing Jing Pharmaceutical Co., Ltd., founded in October 2007, covers an area of 200 mu, registered capital of 257.28 million yuan, and employees of more than 700 people, is a high-tech enterprise specializing in the R&D, production, and marketing of sterile raw materials, amino acids, and vitamin nutrition fortifiers. The company's technical team has obtained more than 40 patents and 7 new product and new technology appraisals. The company has formed two series of products: one is sterile API products with crystallization technology; the other is an amino acid and vitamin series product with biological enzyme catalysis technology.
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LTDLANTAI ROAD NORTH, WUSI TAI TOWN, ALXA ZUOQIECONOMIC DEVELO MENT ZONE, ALXA CITY, INNERMONGOLIA CHINA","customerAddress":"OFFICE NO 501, 5TH FLOOR, K L ACCOLADE, ROAD NO 6"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1759861800,"product":"CREATINE MONOHYDRATE 200 MESH (NOT FOR MEDICINAL USE)(INVOICE NUMBER W2508344SA2508426 DT: 28\/08\/2025)CREATINE MONOHYDRATE 200 MESH ( NOT FOR MEDICINAL USE)","address":"4TH FLOOR, D 426 NEELKANTH BUSINESS PARK","city":"MUMBAI","supplier":"ARSHINE FOOD ADDITIVES CO LTD","supplierCountry":"CHINA","foreign_port":"TIANJIN","customer":"APHRODITE FOODS LLP","customerCountry":"INDIA","quantity":"26000.00","actualQuantity":"26000","unit":"KGS","unitRateFc":"2.6","totalValueFC":"67297.5","currency":"USD","unitRateINR":"228.7","date":"08-Oct-2025","totalValueINR":"5947110","totalValueInUsd":"67297.5","indian_port":"JNPT","hs_no":"29252990","bill_no":"4966408","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"TIANJIN","supplierAddress":"BLOCK NO 14, NO. 100, LUYUN ROAD, H IGH TECH INDUSTRIAL DEVELOPMENT ZON E Changsha, , China China","customerAddress":"4TH FLOOR, D 426 NEELKANTH BUSINESS PARK"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1760898600,"product":"CREATINE MONOHYDRATE 200 MESH (NOT FOR MEDICINAL USE) CREATINE MONOHYDRATE 200 MESH","address":"OFFICE NO 501, 5TH FLOOR, K L ACCOLADE, ROAD NO 6","city":"Mumbai","supplier":"NINGXIA TAIKANG PHARMACEUTICAL CO.L","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"CHEMKART INDIA LTD","customerCountry":"INDIA","quantity":"50000.00","actualQuantity":"50000","unit":"KGS","unitRateFc":"2.5","totalValueFC":"126488.7","currency":"USD","unitRateINR":"223.6","date":"20-Oct-2025","totalValueINR":"11177862","totalValueInUsd":"126488.7","indian_port":"JNPT","hs_no":"29252990","bill_no":"5218266","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"TD..NO. 14 SHANSHUI AVENUE,PINGLUO INDUSTRIAL PARK SDNF CHINA","customerAddress":"OFFICE NO 501, 5TH FLOOR, K L ACCOLADE, ROAD NO 6"}]
    06-Jan-2022
    20-Oct-2025
    KGS
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    Average Price (USD/KGS)

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    Drugs in Development

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    • Development Update
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    Momentous Launches Creatine Chews, Elevating Edible Creatine

    Details:

    Creatine, a protein supplement, targets various creatine kinases and transporters to enhance muscle performance.


    Lead Product(s): Creatine,Inapplicable

    Therapeutic Area: Neurology Brand Name: Creapure

    Study Phase: Approved FDFProduct Type: Protein

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable October 22, 2025

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    01

    Momentous

    Country
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    Momentous

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    Lead Product(s) : Creatine,Inapplicable

    Therapeutic Area : Neurology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Momentous Launches Creatine Chews, Elevating Edible Creatine

    Details : Creatine, a protein supplement, targets various creatine kinases and transporters to enhance muscle performance.

    Product Name : Creapure

    Product Type : Protein

    Upfront Cash : Inapplicable

    October 22, 2025

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    The Effects of Tyrosol and Creatine on Endurance, Strength, and Fatigue Resistance in Healthy Adults

    Details:

    Tyrosol is a Plant Extract/Herbal drug candidate, which is currently being evaluated in clinical studies for the treatment of Creatine Deficiency Syndromes.


    Lead Product(s): CAS 501-94-0,Creatine

    Therapeutic Area: Genetic Disease Brand Name: Undisclosed

    Study Phase: UndisclosedProduct Type: Plant Extract/Herbal

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable March 19, 2025

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    02

    Applied Science & Performance Institute

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    COMPAMED
    Not Confirmed

    Applied Science & Performance Institute

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    COMPAMED
    Not Confirmed
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    Lead Product(s) : CAS 501-94-0,Creatine

    Therapeutic Area : Genetic Disease

    Highest Development Status : Undisclosed

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    The Effects of Tyrosol and Creatine on Endurance, Strength, and Fatigue Resistance in Healthy Adul...

    Details : Tyrosol is a Plant Extract/Herbal drug candidate, which is currently being evaluated in clinical studies for the treatment of Creatine Deficiency Syndromes.

    Product Name : Undisclosed

    Product Type : Plant Extract/Herbal

    Upfront Cash : Inapplicable

    March 19, 2025

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    Effects of Resistance-band Training and Creatine Supplementation Strategies in Healthy Older Adults

    Details:

    Creatine is a Protein drug candidate, which is currently being evaluated in clinical studies for the treatment of Aging.


    Lead Product(s): Creatine,Inapplicable

    Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

    Study Phase: UndisclosedProduct Type: Protein

    Sponsor: Iovate Health Sciences

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable September 23, 2024

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    03

    University of Regina

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    University of Regina

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    COMPAMED
    Not Confirmed
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    Lead Product(s) : Creatine,Inapplicable

    Therapeutic Area : Cardiology/Vascular Diseases

    Highest Development Status : Undisclosed

    Partner/Sponsor/Collaborator : Iovate Health Sciences

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Effects of Resistance-band Training and Creatine Supplementation Strategies in Healthy Older Adult...

    Details : Creatine is a Protein drug candidate, which is currently being evaluated in clinical studies for the treatment of Aging.

    Product Name : Undisclosed

    Product Type : Protein

    Upfront Cash : Inapplicable

    September 23, 2024

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    Creatine Supplementation in Young Healthy Adults

    Details:

    Creatine is a Protein drug candidate, which is currently being evaluated in clinical studies for the treatment of Muscle Cramp.


    Lead Product(s): Creatine,Inapplicable

    Therapeutic Area: Musculoskeletal Brand Name: Undisclosed

    Study Phase: UndisclosedProduct Type: Protein

    Sponsor: Iovate Health Sciences

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable September 20, 2024

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    04

    University of Regina

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    University of Regina

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    COMPAMED
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    Lead Product(s) : Creatine,Inapplicable

    Therapeutic Area : Musculoskeletal

    Highest Development Status : Undisclosed

    Partner/Sponsor/Collaborator : Iovate Health Sciences

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Creatine Supplementation in Young Healthy Adults

    Details : Creatine is a Protein drug candidate, which is currently being evaluated in clinical studies for the treatment of Muscle Cramp.

    Product Name : Undisclosed

    Product Type : Protein

    Upfront Cash : Inapplicable

    September 20, 2024

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    Role of a Dietary Supplement in Lowering SAH in Healthy Adults With Elevated Plasma SAH and Normal Homocysteine Levels

    Details:

    Alpha-GPC is a drug candidate, which is currently being evaluated in clinical studies for the treatment of Elevated S-adenosylhomocysteine.


    Lead Product(s): Alpha-GPC,Creatine,Ashwagandha Sensoril

    Therapeutic Area: Endocrinology Brand Name: Undisclosed

    Study Phase: UndisclosedProduct Type: Undisclosed

    Sponsor: Nutrasource

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable August 16, 2023

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    05

    Standard Process Inc.

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    Standard Process Inc.

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    COMPAMED
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    Lead Product(s) : Alpha-GPC,Creatine,Ashwagandha Sensoril

    Therapeutic Area : Endocrinology

    Highest Development Status : Undisclosed

    Partner/Sponsor/Collaborator : Nutrasource

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Role of a Dietary Supplement in Lowering SAH in Healthy Adults With Elevated Plasma SAH and Normal...

    Details : Alpha-GPC is a drug candidate, which is currently being evaluated in clinical studies for the treatment of Elevated S-adenosylhomocysteine.

    Product Name : Undisclosed

    Product Type : Undisclosed

    Upfront Cash : Inapplicable

    August 16, 2023

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    New Method Using Deuterium Labelled Creatine to Measure Total Body Skeletal Muscle Mass

    Details:

    D3 Creatine is a Protein drug candidate, which is currently being evaluated in clinical studies for the treatment of undefined medical condition.


    Lead Product(s): D3 Creatine,Creatine

    Therapeutic Area: Undisclosed Brand Name: Undisclosed

    Study Phase: UndisclosedProduct Type: Protein

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable August 11, 2015

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    GSK

    United Kingdom
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    COMPAMED
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    GSK

    United Kingdom
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    Lead Product(s) : D3 Creatine,Creatine

    Therapeutic Area : Undisclosed

    Highest Development Status : Undisclosed

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    New Method Using Deuterium Labelled Creatine to Measure Total Body Skeletal Muscle Mass

    Details : D3 Creatine is a Protein drug candidate, which is currently being evaluated in clinical studies for the treatment of undefined medical condition.

    Product Name : Undisclosed

    Product Type : Protein

    Upfront Cash : Inapplicable

    August 11, 2015

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    Effect of Using Whey Protein and Creatine Supplements on Muscular Strength in Weight-training Adult Males

    Details:

    Whey Protein is a Protein drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.


    Lead Product(s): Whey Protein,Creatine

    Therapeutic Area: Undisclosed Brand Name: Undisclosed

    Study Phase: Phase IProduct Type: Protein

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable March 24, 2014

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    GSK

    United Kingdom
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    Not Confirmed

    GSK

    United Kingdom
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    Lead Product(s) : Whey Protein,Creatine

    Therapeutic Area : Undisclosed

    Highest Development Status : Phase I

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Effect of Using Whey Protein and Creatine Supplements on Muscular Strength in Weight-training Adul...

    Details : Whey Protein is a Protein drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

    Product Name : Undisclosed

    Product Type : Protein

    Upfront Cash : Inapplicable

    March 24, 2014

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    A Clinical Study to Investigate the Effects of Creatine Supplementation on Muscle Energetics and Cognitive Function in Young Healthy Male Athletes and a...

    Details:

    Creatine is a Protein drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.


    Lead Product(s): Creatine,Inapplicable

    Therapeutic Area: Undisclosed Brand Name: Undisclosed

    Study Phase: Phase IProduct Type: Protein

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable February 10, 2014

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    GSK

    United Kingdom
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    COMPAMED
    Not Confirmed

    GSK

    United Kingdom
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    COMPAMED
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    Lead Product(s) : Creatine,Inapplicable

    Therapeutic Area : Undisclosed

    Highest Development Status : Phase I

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    A Clinical Study to Investigate the Effects of Creatine Supplementation on Muscle Energetics and C...

    Details : Creatine is a Protein drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

    Product Name : Undisclosed

    Product Type : Protein

    Upfront Cash : Inapplicable

    February 10, 2014

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    Creatine on Bone Mass in Postmenopausal Women

    Details:

    Creatine is a Protein drug candidate, which is currently being evaluated in clinical studies for the treatment of undefined medical condition.


    Lead Product(s): Creatine,Inapplicable

    Therapeutic Area: Undisclosed Brand Name: Undisclosed

    Study Phase: UndisclosedProduct Type: Protein

    Sponsor: AlzChem AG

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable November 16, 2011

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    09

    University of Sao Paulo

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    University of Sao Paulo

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    COMPAMED
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    Lead Product(s) : Creatine,Inapplicable

    Therapeutic Area : Undisclosed

    Highest Development Status : Undisclosed

    Partner/Sponsor/Collaborator : AlzChem AG

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Creatine on Bone Mass in Postmenopausal Women

    Details : Creatine is a Protein drug candidate, which is currently being evaluated in clinical studies for the treatment of undefined medical condition.

    Product Name : Undisclosed

    Product Type : Protein

    Upfront Cash : Inapplicable

    November 16, 2011

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    Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)

    Details:

    Omega-3 Fatty Acid is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Multiple Sclerosis.


    Lead Product(s): Omega-3 Fatty Acid,Full Spectrum Vitamin,Essential - Hydroxytyrosol,Maltodextrin Fiber Supplement,Mineral Boost (Magnesium),Niacinamide,Methyl B12,Taurine,Creatine,Vitamin B1,Riboflavin,Acetylcysteine,Alpha Lipoic Acid,L Acetyl Carnitine,

    Therapeutic Area: Neurology Brand Name: Undisclosed

    Study Phase: Phase IProduct Type: Miscellaneous

    Sponsor: Direct MS Canada | DJO Incorporated | Pinnaclife Inc. | TZ Press, LLC

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable June 27, 2011

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    University of Iowa

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    University of Iowa

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    Lead Product(s) : Omega-3 Fatty Acid,Full Spectrum Vitamin,Essential - Hydroxytyrosol,Maltodextrin Fiber Supplement,Mineral Boost (Magnesium),Niacinamide,Methyl B12,Taurine,Creatine,Vitamin B1,Riboflavin,Acetylcysteine,Alpha Lipoic Acid,L Acetyl Carnitine,

    Therapeutic Area : Neurology

    Highest Development Status : Phase I

    Partner/Sponsor/Collaborator : Direct MS Canada | DJO Incorporated | Pinnaclife Inc. | TZ Press, LLC

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosi...

    Details : Omega-3 Fatty Acid is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Multiple Sclerosis.

    Product Name : Undisclosed

    Product Type : Miscellaneous

    Upfront Cash : Inapplicable

    June 27, 2011

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    FDF Dossiers

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    World Medicine

    Turkey
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    World Medicine

    Turkey
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    Regulatory Info : Generic

    Registration Country : Turkey

    Creatine; Magnesium; Potassium

    Brand Name :

    Dosage Form : SACHET

    Dosage Strength : 500MG; 442MG; 184MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : Turkey

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    Europe

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    World Medicine Ilac San ve tic LTD STl

    Turkey
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    World Medicine Ilac San ve tic LTD STl

    Turkey
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    Regulatory Info : Generic

    Registration Country : Turkey

    Creatine; Magnesium; Potassium

    Brand Name :

    Dosage Form : SACHET

    Dosage Strength : 500MG; 442MG; 184MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : Turkey

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    Momentous Launches Creatine Chews Elevating Edible Creatine
    Momentous Launches Creatine Chews Elevating Edible Creatine

    22 Oct 2025

    // BUSINESSWIRE

    https://www.businesswire.com/news/home/20251022989904/en/Momentous-Launches-Creatine-Chews-Raising-the-Bar-for-Edible-Creatine

    BUSINESSWIRE
    22 Oct 2025
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    Looking for 57-00-1 / Creatine API manufacturers, exporters & distributors?

    Creatine manufacturers, exporters & distributors 1

    14

    PharmaCompass offers a list of Creatine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Creatine manufacturer or Creatine supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Creatine manufacturer or Creatine supplier.

    PharmaCompass also assists you with knowing the Creatine API Price utilized in the formulation of products. Creatine API Price is not always fixed or binding as the Creatine Price is obtained through a variety of data sources. The Creatine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Creatine

    Synonyms

    57-00-1, N-amidinosarcosine, Creatin, Kreatin, Krebiozon, N-methyl-n-guanylglycine

    Cas Number

    57-00-1

    Unique Ingredient Identifier (UNII)

    MU72812GK0

    About Creatine

    An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine.

    Creatine Manufacturers

    A Creatine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Creatine, including repackagers and relabelers. The FDA regulates Creatine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Creatine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Creatine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Creatine Suppliers

    A Creatine supplier is an individual or a company that provides Creatine active pharmaceutical ingredient (API) or Creatine finished formulations upon request. The Creatine suppliers may include Creatine API manufacturers, exporters, distributors and traders.

    click here to find a list of Creatine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Creatine GMP

    Creatine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Creatine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Creatine GMP manufacturer or Creatine GMP API supplier for your needs.

    Creatine CoA

    A Creatine CoA (Certificate of Analysis) is a formal document that attests to Creatine's compliance with Creatine specifications and serves as a tool for batch-level quality control.

    Creatine CoA mostly includes findings from lab analyses of a specific batch. For each Creatine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Creatine may be tested according to a variety of international standards, such as European Pharmacopoeia (Creatine EP), Creatine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Creatine USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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