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1. Hexafluoride, Sulfur
1. Sulphur Hexafluoride
2. 2551-62-4
3. Sulfur Fluoride
4. Sonovue
5. Elegas
6. Sulfur Fluoride (sf6)
7. Lumason
8. Sulfur(vi) Fluoride
9. Hexafluorure De Soufre
10. Hexafluoridosulfur
11. Sulfur Hexafluoride [usan]
12. Sulfur Fluoride (sf6), (oc-6-11)-
13. Sulfur(6+) Fluoride
14. Ws7lr3i1d6
15. Chebi:30496
16. Bri
17. Hexafluorosulfur
18. Sulfur Hexafluoride (usan)
19. Esaflon
20. Elagas
21. Sf6
22. Hsdb 825
23. Hexafluorure De Soufre [french]
24. Einecs 219-854-2
25. Sulfur Hexafluoride Lipid Microsphere
26. Un1080
27. Unii-ws7lr3i1d6
28. Sf6 Microbubbles
29. Sulfur Fluoride, (oc-6-11)-
30. Lumason (tn)
31. Sonovue (tn)
32. Hexafluoro-l6-sulfane
33. Hexafluoro-lambda6-sulfane
34. Ec 219-854-2
35. R 7146
36. Hexafluoro-$l^{6}-sulfane
37. Chembl1796998
38. Dtxsid8029656
39. Sulfur Hexafluoride [mi]
40. [sf6]
41. Sulfur Hexafluoride [hsdb]
42. Sulfur Hexafluoride, >=99.75%
43. Amy37163
44. Hexakis(fluoranyl)-$l^{6}-sulfane
45. Sulfur Hexafluoride [mart.]
46. Mfcd00011447
47. Sulfur Hexafluoride [who-dd]
48. Zinc245224194
49. Db11104
50. Oc-6-11
51. Sulphur Hexafluoride [ema Epar]
52. Un 1080
53. Sonovue (for The Microbubble Formulation)
54. Stabilized Sulfur Hexafluoride Microbubbles
55. Sulfur Hexafluoride, Phospholipid Microspheres
56. D05962
57. A817889
58. Q279055
59. Sulfur Hexafluoride [un1080] [nonflammable Gas]
60. Sulfur Hexafluoride Lipid-type A Microspheres [orange Book]
| Molecular Weight | 146.06 g/mol |
|---|---|
| Molecular Formula | F6S |
| XLogP3 | 4.2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 0 |
| Exact Mass | 145.96249015 g/mol |
| Monoisotopic Mass | 145.96249015 g/mol |
| Topological Polar Surface Area | 1 Ų |
| Heavy Atom Count | 7 |
| Formal Charge | 0 |
| Complexity | 62.7 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
| 1 of 2 | |
|---|---|
| Drug Name | Lumason |
| Active Ingredient | Sulfur hexafluoride lipid-type a microspheres |
| Dosage Form | For suspension |
| Route | Intravenous |
| Strength | 60.7mg/25mg |
| Market Status | Prescription |
| Company | Bracco |
| 2 of 2 | |
|---|---|
| Drug Name | Lumason |
| Active Ingredient | Sulfur hexafluoride lipid-type a microspheres |
| Dosage Form | For suspension |
| Route | Intravenous |
| Strength | 60.7mg/25mg |
| Market Status | Prescription |
| Company | Bracco |
Lumason is indicated for use in patients with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border.
NIH; DailyMed. Current Medication Information for LUMASON- sulfur hexafluoride (Revised: October 2014). Available from, as of August 2, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089
An inert gas used mainly as a test gas in respiratory physiology. Other uses include its injection in vitreoretinal surgery to restore the vitreous chamber ...
National Library of Medicine - Medical Subject Headings (2007)
The intraocular injection of sulfur hexafluoride appears to be useful contribution to the surgical treatment of superior bullous hemi-retinal detachment, allowing effective and durable internal tamponade, while avoiding prolonged bedrest.
J Fr Ophtalmol 6 (11): 889-93 (1983)
In this randomized clinical trial, 18 patients received treatment with silicone oil and 16 patients received SF6. The primary outcome was defined as successful anatomic attachment of the retina. Secondary outcomes included the time to retinal detachment, visual acuity, anatomic macular attachment, and any complications of surgery. RESULTS: The odds of successful reattachment with silicone oil were 50% greater than they were with SF6, but this difference was not statistically significant. There were no differences between the two groups in any of the secondary outcomes. ... This study did not have enough statistical power to detect a small but clinically important difference between the two treatment groups ...
PMID:9387180 Hammer M et al; Ophthalmic Surg Lasers 28 (11): 926-31 (1997)
For more Therapeutic Uses (Complete) data for SULFUR HEXAFLUORIDE (11 total), please visit the HSDB record page.
/BOXED WARNING/ WARNING: SERIOUS CARDIOPULMONARY REACTIONS Serious cardiopulmonary reactions, including fatalities, have occurred uncommonly during or following the injection of ultrasound contrast agents, including sulfur hexafluoride lipid microspheres. Most serious reactions occur within 30 minutes of administration. Assess all patients for the presence of any condition that precludes administration. Always have resuscitation equipment and trained personnel readily available.
NIH; DailyMed. Current Medication Information for LUMASON- sulfur hexafluoride (Revised: October 2014). Available from, as of August 2, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089
Serious cardiopulmonary reactions, including fatalities have occurred uncommonly during or shortly following administration of ultrasound contrast agents, including Lumason. These reactions typically occurred within 30 minutes of administration. The risk for these reactions may be increased among patients with unstable cardiopulmonary conditions (acute myocardial infarction, acute coronary artery syndromes, worsening or unstable congestive heart failure, or serious ventricular arrhythmias). Always have cardiopulmonary resuscitation personnel and equipment readily available prior to Lumason administration and monitor all patients for acute reactions. The reported reactions that may follow the administration of ultrasound contrast agents include: fatal cardiac or respiratory arrest, shock, syncope, symptomatic arrhythmias (atrial fibrillation, tachycardia, bradycardia, supraventricular tachycardia, ventricular fibrillation, and ventricular tachycardia), hypertension, hypotension, dyspnea, hypoxia, chest pain, respiratory distress, stridor, wheezing, loss of consciousness, and convulsions.
NIH; DailyMed. Current Medication Information for LUMASON- sulfur hexafluoride (Revised: October 2014). Available from, as of August 2, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089
Lumason is contraindicated in patients with: known or suspected right-to-left, bi-directional, or transient right-to-left cardiac shunts history of hypersensitivity reactions to sulfur hexafluoride lipid microsphere components or to any of the inactive ingredients in Lumason Do not administer by intra-arterial injection.
NIH; DailyMed. Current Medication Information for LUMASON- sulfur hexafluoride (Revised: October 2014). Available from, as of August 2, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089
In patients with right-to-left, bi-directional, or transient right-to-left cardiac shunts, some intravenously injected sulfur hexafluoride lipid containing microspheres may bypass filtering by the lung and directly enter the arterial circulation. Occlusion of the microcirculation by these microspheres may result in tissue ischemia. Lumason is only for intravenous administration; do not administer Lumason by intra-arterial injection.
NIH; DailyMed. Current Medication Information for LUMASON- sulfur hexafluoride (Revised: October 2014). Available from, as of August 2, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089
For more Drug Warnings (Complete) data for SULFUR HEXAFLUORIDE (19 total), please visit the HSDB record page.
Echocardiography: Sulfur hexafluoride is indicated for use in adult patients with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricularendocardial border. Ultrasonography of the Liver: Sulfur hexafluoride is indicated for use with ultrasound of the liver in adult and pediatric patients to characterize focal liver lesions.
This medicinal product is for diagnostic use only.
SonoVue is for use with ultrasound imaging to enhance the echogenicity of the blood, or of fluids in the urinary tract which results in an improved signal to noise ratio.
SonoVue should only be used in patients where study without contrast enhancement is inconclusive.
Echocardiography
SonoVue is a transpulmonary echocardiographic contrast agent for use in adult patients with suspected or established cardiovascular disease to provide opacification of cardiac chambers and enhance left ventricular endocardial border delineation.
Doppler of macrovasculature
SonoVue increases the accuracy in detection or exclusion of abnormalities in cerebral arteries and extracranial carotid or peripheral arteries in adult patients by improving the Doppler signal to noise ratio.
SonoVue increases the quality of the Doppler flow image and the duration of clinically useful signal enhancement in portal vein assessment in adult patients.
Doppler of microvasculature
SonoVue improves display of the vascularity of liver and breast lesions during Doppler sonography in adult patients leading to more specific lesion characterisation.
Ultrasonography of excretory urinary tract
SonoVue is indicated for use in ultrasonography of the excretory tract in paediatric patients from newborn to 18 years to detect vesicoureteral reflux. For the limitation in the interpretation of a negative urosonography.
Sulfur hexafluoride provides useful echocardiographic signal intensity for two minutes after the injection. Sulfur hexafluoride microspheres are destroyed and contrast enhancement decreases as the mechanical index increases (values of 0.8 or less are recommended). For ultrasonography of the liver, Sulfur hexafluoride provides dynamic patterns of differential signal intensity enhancement between focal liver lesions and liver parenchyma during the arterial, portal venous, and late phase of signal intensity enhancement of the microvasculature.
V08DA04
V08DA05
S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355
V - Various
V08 - Contrast media
V08D - Ultrasound contrast media
V08DA - Ultrasound contrast media
V08DA05 - Sulfur hexafluoride, phospholipid microspheres
Absorption
The pharmacokinetic of the SF6 gas component of Lumason was evaluated in 12 healthy adult subjects (7 men and 5 women). After intravenous bolus injections of 0.03 mL/kg and 0.3 mL/kg of Lumason, corresponding to approximately 1 and 10 times the recommended doses, concentrations of SF6 in blood peaked within 1 to 2 minutes for both doses.
Route of Elimination
The SF6 component of Lumason is eliminated via the lungs.
Volume of Distribution
In a study of healthy subjects, the mean values for the apparent steady-state volume of distribution of SF6 were 341 L and 710 L for Lumason doses of 0.03 mL/kg and 0.3 mL/kg, respectively. Preferential distribution to the lung is likely responsible for these values.
SonoVue, is a new echo contrast agent based on stabilized sulfur hexafluoride (SF6) microbubbles ... The blood kinetics and pulmonary elimination of SF6 after intravenous bolus injection of two dosage levels (0.03 and 0.3 mL/kg) of SonoVue were evaluated in 12 healthy subjects (7 men, 5 women). In addition, safety and tolerability were evaluated by monitoring vital signs, adverse effects, discomfort, and physical examination and laboratory parameters associated with the SonoVue injection. The blood kinetics of SF6 was not dose dependent. SF6 was rapidly removed from the blood by the pulmonary route, with 40% to 50% of the injected dose eliminated within the first minute after administration and 80% to 90% eliminated by 11 minutes after administration; the elimination was similar in men and women and independent of dose. Both dosages were well tolerated. No adverse effects were observed immediately or during the 24-hour follow-up period. ... The route of SF6 elimination was by means of the lungs in the expired air. ...
PMID:10639039 Morel DR et al; Invest Radiol 35 (1): 80-5 (2000)
Sonovue (trade mark) is a new echo contrast agent made of microbubbles stabilized by phospholipids and containing sulphur hexafluoride (SF6), an innocuous gas. ... With regard to the gas contained in the bubbles, its pharmacokinetics have been assessed during a study in human volunteers. Following intravenous administration of 0.3 mL/kg of SonoVue (trade mark) (i.e., approximately ten times the imaging dose), the blood level curve showed a distribution half-life of about 1 minute and an elimination half-life of about 6 minutes. More than 80% of the administered gas is exhaled via the lungs after 11 minutes. ...
PMID:10639039 Schneider M; Echocardiography 16 (7, Pt 2): 743-746 (1999 Oct)
The pharmacokinetic of the SF6 gas component of Lumason was evaluated in 12 healthy adult subjects (7 men and 5 women). After intravenous bolus injections of 0.03 mL/kg and 0.3 mL/kg of Lumason, corresponding to approximately 1 and 10 times the recommended doses, concentrations of SF6 in blood peaked within 1 to 2 minutes for both doses. The terminal half-life of SF6 in blood was approximately 10 minutes for the 0.3 mL/kg dose. (At the 0.03 mL/kg dose, terminal half-life could not be estimated.) The area-under-the-curve of SF6 was dose-proportional over the dose range studied.
NIH; DailyMed. Current Medication Information for LUMASON- sulfur hexafluoride (Revised: October 2014). Available from, as of August 2, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089
In a study of healthy subjects, the mean values for the apparent steady-state volume of distribution of SF6 were 341 L and 710 L for Lumason doses of 0.03 mL/kg and 0.3 mL/kg, respectively. Preferential distribution to the lung is likely responsible for these values.
NIH; DailyMed. Current Medication Information for LUMASON- sulfur hexafluoride (Revised: October 2014). Available from, as of August 2, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089
For more Absorption, Distribution and Excretion (Complete) data for SULFUR HEXAFLUORIDE (6 total), please visit the HSDB record page.
SF6 undergoes little or no biotransformation; 88% of an administered dose is recovered unchanged in expired air.
SF6 undergoes little or no biotransformation; 88% of an administered dose is recovered unchanged in expired air.
NIH; DailyMed. Current Medication Information for LUMASON- sulfur hexafluoride (Revised: October 2014). Available from, as of August 2, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089
Under brief and prolonged exposures, sulfur hexafluoride was biologically inert and did not metabolize.
PMID:7250729 Mel'nikova LV, Rozova TA; Gig Tr Prof Zabol 6: 48-9 (1981)
The terminal half-life of SF6 in blood was approximately 10 minutes for the 0.3 mL/kg dose. (At the 0.03 mL/kg dose, terminal half-life could not be estimated.)
The pharmacokinetic of the SF6 gas component of Lumason was evaluated in 12 healthy adult subjects (7 men and 5 women). After intravenous bolus injections of 0.03 mL/kg and 0.3 mL/kg of Lumason... The terminal half-life of SF6 in blood was approximately 10 minutes for the 0.3 mL/kg dose. (At the 0.03 mL/kg dose, terminal half-life could not be estimated.) The area-under-the-curve of SF6 was dose-proportional over the dose range studied.
NIH; DailyMed. Current Medication Information for LUMASON- sulfur hexafluoride (Revised: October 2014). Available from, as of August 2, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089
... Following intravenous administration of 0.3 mL/kg of SonoVue (trade mark) (i.e., approximately ten times the imaging dose), the blood level curve showed a distribution half-life of about 1 minute and an elimination half-life of about 6 minutes. ...
PMID:10639039 Schneider M; Echocardiography 16 (7, Pt 2): 743-746 (1999 Oct)
In a study of patients with pulmonary impairment, blood concentrations of SF6 peaked at 1 to 4 minutes following Lumason administration. The cumulative recovery of SF6 in expired air was 102 +/- 18% (mean +/- standard deviation), and the terminal half-life of SF6 in blood was similar to that measured in healthy subjects.
NIH; DailyMed. Current Medication Information for LUMASON- sulfur hexafluoride (Revised: October 2014). Available from, as of August 2, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7c679424-c3f7-ed02-892f-20ca0d775089
Within the blood, the acoustic impedance of Lumason microspheres is lower than that of the surrounding non-aqueous tissue. Therefore, an ultrasound beam is reflected from the interface between the microspheres and the surrounding tissue. The reflected ultrasound signal provides a visual image that shows a contrast between the blood and the surrounding tissues.
API SUPPLIERS
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USDMF
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 15094
Submission : 2000-10-13
Status : Active
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 37317
Submission : 2023-03-24
Status : Active
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 1888
Submission : 1972-03-08
Status : Inactive
Type : II
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KDMF
Registrant Name : Braco Imaging Korea Co., Ltd.
Registration Date : 2005-06-14
Registration Number : Number 267-1-ND
Manufacturer Name : Airgas Therapeutics, LLC
Manufacturer Address : 6141 Easton Road-Building 3, Plumsteadville, PA 18949-0310
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RLD : Yes
TE Code :
SULFUR HEXAFLUORIDE LIPID-TYPE A MICROSPHERES
Brand Name : LUMASON
Dosage Form : FOR SUSPENSION;INTRAVENOUS
Dosage Strength : 60.7MG/25MG
Approval Date : 2014-10-15
Application Number : 203684
RX/OTC/DISCN : RX
RLD : Yes
TE Code :
RLD : No
TE Code :
Brand Name : BENSULFOID
Dosage Form : POWDER;TOPICAL
Dosage Strength : 33.32%
Approval Date : 1982-01-01
Application Number : 2918
RX/OTC/DISCN : DISCN
RLD : No
TE Code :
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Regulatory Info :
Registration Country : Sweden
Brand Name : SonoVue
Dosage Form : POWDER AND SOLVENT FOR SOLUTION FOR INJECTION
Dosage Strength : 8 MICROL / ML
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Sweden
Regulatory Info :
Registration Country : Italy
Brand Name : Sonovue
Dosage Form : Sulfur Hexafluoride, 8Mcl/Ml 5Ml 1 Units Parenteral Use
Dosage Strength : 8 mcl/ml 1 vial + 1 syringe 5 ml + Adapter
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Italy
Regulatory Info :
Registration Country : Norway
Brand Name : SonoVue
Dosage Form : Powder and liquid to the injection fluid, Dispersion
Dosage Strength : 8 micro liters/ml
Packaging : Set
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Norway
Regulatory Info :
Registration Country : Switzerland
Brand Name : Sonovue
Dosage Form : Dry Sub C Solv
Dosage Strength :
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Switzerland
Regulatory Info :
Registration Country : Switzerland
Brand Name : Ektoselen medicinal shampoo
Dosage Form : Solution
Dosage Strength :
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Switzerland
Regulatory Info :
Registration Country : Switzerland
Brand Name : Ektoselen medicinal shampoo
Dosage Form : Solution
Dosage Strength :
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Switzerland
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Regulatory Info : Ethical
Registration Country : Canada
Brand Name : SONOVUE
Dosage Form : POWDER FOR SUSPENSION
Dosage Strength : 8MCL/ML
Packaging :
Approval Date :
Application Number : 2287684
Regulatory Info : Ethical
Registration Country : Canada
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Regulatory Info :
Registration Country : Turkey
Brand Name :
Dosage Form : Ophthalmic Gas
Dosage Strength : 10ML
Packaging :
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Regulatory Info :
Registration Country : Turkey
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FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Actylis
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Aeon Procare
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Alcedo Pharmachem
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]BASF
Dosage Form : Emulsion
Grade : Not Available
Application : Topical
Excipient Details : Medium spreadability, solvent for lipophilic drugs, enhances skin penetration
Pharmacopoeia Ref : Ph. Eur., USP-NF: Oleyl alcoho...
Technical Specs : Not Available
Ingredient(s) : Oleyl Alcohol
Dosage Form : Emulsion
Grade : Not Available
Application : Topical
Excipient Details : Medium spreadability, solvent for lipophilic drugs, enhances skin penetration, effective in exceptionally wide pH range
Pharmacopoeia Ref : Ph. Eur., USP-NF: Octyldodecan...
Technical Specs : Not Available
Ingredient(s) : Octyldodecanol
Dosage Form : Tablet
Grade : Not Available
Application : Granulation
Excipient Details : For non-erodible matrices using direct compression, Controlled release matrix. Matrix former in transdermal patches and topical films.
Pharmacopoeia Ref : Ph. Eur., USP-NF, JP-JPE: 80 %...
Technical Specs : Not Available
Ingredient(s) : Hydrated Silica
Dosage Form : Tablet
Grade : Not Available
Application : Film Formers & Plasticizers
Excipient Details : Liquid plasticizer with high ADI, hydrophilic solvent & humectant in emulsions, skin penetration enhancer in topical formulaitons.
Pharmacopoeia Ref : Ph. Eur., JP, FCC, USP
Technical Specs : Not Available
Ingredient(s) : Propylene Glycol
Dosage Form : Cream / Lotion / Ointment
Grade : Not Available
Application : Topical
Excipient Details : Structure-building consistency factor for semi-solids. Viscosity regulator.
Pharmacopoeia Ref : Ph. Eur., USP-NF: Cetyl alcoho...
Technical Specs : Not Available
Ingredient(s) : Cetyl Alcohol
Dosage Form : Capsule
Grade : Not Available
Application : Lubricants & Glidants
Excipient Details : Lipophilic lubricant, for sensitive acidic APIs, sustained release melt coating. Used as consistency factor to enhance the viscosity of topical formulations.
Pharmacopoeia Ref : Ph. Eur., Castor Oil, hydrogen...
Technical Specs : Not Available
Ingredient(s) : Hydrogenated Castor Oil
Dosage Form : Softgel Capsule
Grade : Not Available
Application : Thickeners and Stabilizers
Excipient Details : Structure-building consistency factor with dry feel, forms crystalline barrier on skin
Pharmacopoeia Ref : Ph. Eur., USP-NF, JP: Stearic ...
Technical Specs : Not Available
Ingredient(s) : Stearic Acid
Dosage Form : Tablet
Grade : Not Available
Application : Granulation
Excipient Details : Lipophilic lubricant, for sensitive acidic APIs, Structure-building consistency factor for semi-solids, Viscosity regulator.
Pharmacopoeia Ref : Ph. Eur., USP-NF, JP: Stearyl ...
Technical Specs : Not Available
Ingredient(s) : Stearyl Alcohol
Dosage Form : Orodispersible Tablet
Grade : Not Available
Application : Chewable & Orodispersible Aids
Excipient Details : Ludiflash is a ready-to-use orally disintegrating tablet (ODT) solution with superior mouthfeel.
Pharmacopoeia Ref : Ph. Eur., USP, JP: 90 % mannit...
Technical Specs : Not Available
Ingredient(s) : Crospovidone
Dosage Form : Granule / Pellet
Grade : Not Available
Application : Direct Compression
Excipient Details : Ready-to-use direct compression solution for tablets.
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Bioplus Life Sciences
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]BioSpectra
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Clariant
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Corel Pharma Chem
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]DFE Pharma
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Finar
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Gangwal Chemicals
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Huzhou Sunflower Pharmaceutical
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Ideal Cures Pvt Ltd
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Ingredion Pharma Solutions
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Kerry
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Kima Chemical
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Lonza Capsugel
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Lubrizol Life Science Health
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Microlex e.U
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Nanjing Bold Chemical
Dosage Form : Tablet
Grade : Oral, Topical & Parenteral
Application : Solubilizers
Excipient Details : Polysorbate 80 acts as solubilizer, emulsifier and wetting agent.
Dosage Form : Tablet
Grade : Oral & Topical
Application : Solubilizers
Excipient Details : Sorbitan Monooleate (Span 80) is used as oily emulsifier, solubilizer, thickener.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Sorbitan Monooleate
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Nomisma Healthcare
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Novo Excipients
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Pharmatrans-Sanaq
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Pluviaendo
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Prachin Chemical
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Qianhao Chemical (Hebei) Co., Ltd
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Qualicaps
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Roquette
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Seppic
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Shandong Focus Biotechnology Co., Ltd
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Shanghai Shenmei Pharmaceutical Technology Co., Ltd
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Shijiazhuang Huaxu Pharmaceutical
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Sigachi Industries
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]The Dow Chemical Company
Dosage Form : Tablet
Grade : Not Available
Brand Name : AFFINISOL HPMC HME
Application : Solubilizers
Excipient Details : Solubility enhancement, Spray-Dried Dispersion (SDD), Hot Melt Extrusion (HME)
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Hydroxypropyl Methylcellulose
Dosage Form : Capsule
Grade : Not Available
Application : Rheology Modifiers
Excipient Details : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Hydroxypropyl Methylcellulose
Dosage Form : Tablet
Grade : Not Available
Application : Rheology Modifiers
Excipient Details : Tablet Coating, Rheology Modifier
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Carboxymethyl cellulose sodium
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]TopChem Pharmaceuticals
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Valens Pharmachem
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Vasa Pharmachem
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Zhejiang Huakang Pharmaceutical
Dosage Form : Syrup
Grade : Oral and Topical
Application : Taste Masking
Dosage Form : Tablet
Grade : Oral & Topical
Application : Taste Masking
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Excipients by Applications
Fillers, Diluents & Binders
Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.
Application : Fillers, Diluents & Binders, Taste Masking
Excipient Details : Mannitol is mainly used as a bulking agent in tableting. It is also used as taste masking agent in ODT formulations.
Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.
Dosage Form : Orodispersible Tablet, Tablet
Grade : Oral
Category : Chewable & Orodispersible Aids, Fillers, Diluents & Binders, Taste Masking
Application : Chewable & Orodispersible Aids, Fillers, Diluents & Binders, Taste Masking
Excipient Details : Maltodextrin, derived from the partial hydrolysis of starch, used in tablet formulations as a binder and diluent. It is particularly useful in chewable tablet formulations.
Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.
Dosage Form : Cream / Lotion / Ointment, Emulsion, Gel, Solution, Tablet
Grade : Topical, Oral
Category : API Stability Enhancers, Emulsifying Agents, Fillers, Diluents & Binders
Application : API Stability Enhancers, Emulsifying Agents, Fillers, Diluents & Binders
Excipient Details : Acacia, also known as gum arabic, is used in the pharmaceutical industry as an emulsifier, stabilizing agent, and tablet binder in various formulations.
SPI Pharma has been solving formulation challenges using superior functional materials.
Dosage Form : Orodispersible Tablet, Tablet
Grade : Oral
Category : Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders, Taste Masking
Application : Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders, Taste Masking
Excipient Details : Pharmaburst® 500 is a directly compressible pharmaceutical excipient used to create orally disintegrating tablets quickly and easily.
SPI Pharma has been solving formulation challenges using superior functional materials.
Dosage Form : Tablet
Grade : Oral
Category : Direct Compression, Fillers, Diluents & Binders, Taste Masking
Brand Name : Mannogem® XL Opal
Application : Direct Compression, Fillers, Diluents & Binders, Taste Masking
Excipient Details : Mannogem® XL Opal, directly compressible 160 µm spray-dried mannitol provides superior binding properties and tabletability.
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Brand Name : CALCITEC PURO PH V/40S HT
Application : Fillers, Diluents & Binders
Excipient Details : Calcitec Puro PHV/40S HT is used as filler and binder in oral solid dosage forms including tablets, capsules, granules, and pellets.
Jai Radhe Sales is your partner for all your sourcing needs.
Dosage Form : Capsule, Orodispersible Tablet, Tablet
Grade : Oral
Category : Disintegrants & Superdisintegrants, Fillers, Diluents & Binders
Brand Name : Croscarmellose Sodium
Application : Disintegrants & Superdisintegrants, Fillers, Diluents & Binders
Boai NKY Pharmaceuticals Ltd. is one of the largest global PVP suppliers.
Dosage Form : Tablet
Grade : Oral (Pharma Grade)
Category : Direct Compression, Fillers, Diluents & Binders, Film Formers & Plasticizers
Application : Direct Compression, Fillers, Diluents & Binders, Film Formers & Plasticizers
Excipient Details : KoVidone® VA64 is used as a binder in tablets, direct compression binder, matrix formers in amorphous solid dispersions, and film-forming polymer.
Pharmacopoeia Ref : USP/NF, EP, JP, KP, IP, BP
Technical Specs : NA
Ingredient(s) : Polyvinylpyrrolidone and Vinyl Acetate Copolymer
Gangwal Healthcare is powered by innovation, driving health, wellness & healing.
Grade : Oral
Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders
Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders
Excipient Details : STARLOSE is used as a diluent, binder, directly compressible (DC), and co-processed excipient in tablets and capsules.
Gangwal Healthcare is powered by innovation, driving health, wellness & healing.
Grade : Oral
Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Thickeners and Stabilizers
Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Thickeners and Stabilizers
Excipient Details : DiCOM-DC SP204 is used as a stabilizer, filler, binder, directly compressible, and co-processed excipient in tablets and capsules.
Topical
Evonik's CDMO solutions for APIs and HPAPIs: It specializes where the client needs it most!
Dosage Form : Capsule, Cream / Lotion / Ointment, Tablet
Grade : Oral, Topical
Category : Lubricants & Glidants, Taste Masking, Topical
Application : Lubricants & Glidants, Taste Masking, Topical
Excipient Details : L-Leucine is used as a lubricating & taste masking agent in oral solids such as tablets & capsules and topical formulations such as creams & lotions.
Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.
Dosage Form : Capsule, Orodispersible Tablet, Tablet
Grade : Oral
Category : Chewable & Orodispersible Aids, Coating Systems & Additives, Fillers, Diluents & Binders
Application : Chewable & Orodispersible Aids, Coating Systems & Additives, Fillers, Diluents & Binders
Excipient Details : Xylitol is used as coating agent & filler, binder agent in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets.
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Cream / Lotion / Ointment, Ophthalmic Solution
Grade : Topical, Parenteral
Category : Solubilizers, Topical
Application : Solubilizers, Topical
Excipient Details : Syntadex 7702 is used as a solubilizer in ophthalmic drug products and in topical formulations such as creams, lotions, and ointments.
Jai Radhe Sales is your partner for all your sourcing needs.
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Category : Emulsifying Agents, Solubilizers, Surfactant & Foaming Agents, Topical
Application : Emulsifying Agents, Solubilizers, Surfactant & Foaming Agents, Topical
Excipient Details : Polysorbate 80 is a nonionic surfactant and emulsifier often used topical dosage forms such as cream, lotion, ointment, etc.
Nippon provides high-performance, high-value-added cosmetic, pharmaceutical, and industrial raw materials.
Dosage Form : Cream / Lotion / Ointment, Emulsion, Injectable / Parenteral
Grade : Topical, Parenteral
Category : Emulsifying Agents, Parenteral, Solubilizers, Surfactant & Foaming Agents, Topical
Application : Emulsifying Agents, Parenteral, Solubilizers, Surfactant & Foaming Agents, Topical
Excipient Details : Cholesterol is used as emulsifier, solubilizer, surfactant in parenteral and topical formulations such as cream, lotion and ointments.
Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.
Dosage Form : Cream / Lotion / Ointment, Emulsion, Gel, Injectable / Parenteral, Suspension, Tablet
Grade : Parenteral, Oral, Topical
Category : Emulsifying Agents, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical
Application : Emulsifying Agents, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical
Excipient Details : Polysorbate 20 is used in parenteral products such as biologics. It is used as a solubilizer, surfactant, emulsifier & suspension stabilizer.
Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.
Dosage Form : Cream / Lotion / Ointment, Emulsion, Gel, Tablet
Grade : Oral, Topical
Category : Emulsifying Agents, Solubilizers, Topical
Brand Name : Polyoxyl 40 Stearate
Application : Emulsifying Agents, Solubilizers, Topical
Excipient Details : Polyoxyl (40) stearate is used as an emulsifier, solubilizer & wetting agent in oral & topical dosage forms such as creams, lotions, ointments, etc.
Pharmacopoeia Ref : ChP/USP/EP/JP
Technical Specs : NA
Ingredient(s) : Polyoxyl 40 Stearate Excipient
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Application : Topical
Excipient Details : Boric acid is used as an antimicrobial preservative in topical formulations such as creams and ointments.
Pharmacopoeia Ref : EP
Technical Specs : 99.9 % Boric Acid (H3BO3)
Ingredient(s) : Boric Acid Excipient
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Application : Topical
Excipient Details : Triethanolamine is widely used in topical pharmaceutical formulations primarily in the formation of emulsions and sunscreen.
Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.
Dosage Form : Cream / Lotion / Ointment, Gel, Tablet
Grade : Oral, Topical
Category : Solubilizers, Topical
Brand Name : Polyoxyl 20 Cetostearyl Ether
Application : Solubilizers, Topical
Excipient Details : Polyoxyl 20 cetostearyl ether is used as a wetting agent in OSDs. It is also used as a solubilizer in topical formulations such as lotions and gels.
Solubilizers
Thickeners and Stabilizers
Coating Systems & Additives
Direct Compression
Parenteral
Controlled & Modified Release
Emulsifying Agents
Granulation
Taste Masking
Film Formers & Plasticizers
Surfactant & Foaming Agents
Lubricants & Glidants
Chewable & Orodispersible Aids
Co-Processed Excipients
Disintegrants & Superdisintegrants
Rheology Modifiers
API Stability Enhancers
Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.
Dosage Form : Cream / Lotion / Ointment, Emulsion, Gel, Solution, Tablet
Grade : Topical, Oral
Category : API Stability Enhancers, Emulsifying Agents, Fillers, Diluents & Binders
Application : API Stability Enhancers, Emulsifying Agents, Fillers, Diluents & Binders
Excipient Details : Acacia, also known as gum arabic, is used in the pharmaceutical industry as an emulsifier, stabilizing agent, and tablet binder in various formulations.
SPI Pharma has been solving formulation challenges using superior functional materials.
Dosage Form : Tablet, Orodispersible Tablet
Grade : Oral
Category : API Stability Enhancers, Chewable & Orodispersible Aids, Fillers, Diluents & Binders
Brand Name : Mannogem XL Mannitol
Application : API Stability Enhancers, Chewable & Orodispersible Aids, Fillers, Diluents & Binders
Excipient Details : Mannogem® XL is a DC spray-dried mannitol used to enhance mannitol formulation tabletability & provide superior binding & quick disintegration.
Pharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.
Dosage Form : Cream / Lotion / Ointment, Capsule, Gel, Tablet
Grade : Oral, Topical
Category : API Stability Enhancers, Thickeners and Stabilizers
Application : API Stability Enhancers, Thickeners and Stabilizers
Excipient Details : Xanthan Gum is widely used in oral dosage forms as a suspending and thickening agent. It is also used in topical formulations as stabilizer.
Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.
Dosage Form : Cream / Lotion / Ointment, Suspension
Grade : Topical
Category : API Stability Enhancers, Thickeners and Stabilizers
Application : API Stability Enhancers, Thickeners and Stabilizers
Excipient Details : Xanthan gum is a polysaccharide with many industrial uses, including as a common food additive. It is an effective thickening agent and stabilizer in topicals.
Brand Name : Potassium Carbonate
Application : API Stability Enhancers
Excipient Details : Potassium Carbonate is used as an alkalinizing and stabilizing agent in effervescent tablets.
Application : API Stability Enhancers, Thickeners and Stabilizers
Excipient Details : Adsorbent, Moisture Protection, Stabilization of API
Pharmacopoeia Ref : USP-NF, JP, EP
Technical Specs : Also Available as FUJISIL-F
Ingredient(s) : Silicon Dioxide
Grade : Not Available
Category : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules
Application : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules
Excipient Details : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Hydroxypropyl Methylcellulose
Dosage Form : Capsule
Grade : Oral and Inhalation
Category : API Stability Enhancers, Vegetarian Capsules
Application : API Stability Enhancers, Vegetarian Capsules
Pharmacopoeia Ref : Certified Vegan, Non-GMO, Vege...
Technical Specs : "Water content – less than 9%, can be customized; Size # 00el -...
Ingredient(s) : Hydroxypropyl Methyl Cellulose
Dosage Form : Capsule
Grade : Oral
Category : API Stability Enhancers, Taste Masking, Vegetarian Capsules
Application : API Stability Enhancers, Taste Masking, Vegetarian Capsules
Pharmacopoeia Ref : Certified Vegan, Non-GMO, Vege...
Technical Specs : Size # 0-1
Ingredient(s) : Hydroxypropyl Methyl Cellulose
Dosage Form : Capsule, Tablet, Dry Syrup
Grade : Oral
Category : Co-Processed Excipients, Direct Compression, Solubilizers
Application : Co-Processed Excipients, Direct Compression, Solubilizers
Excipient Details : Solubilizer
Pharmacopoeia Ref : Not Available
Technical Specs : Solubilizer in powder form; EXCiPACT
Ingredient(s) : Polyoxyl 40 hydrogenated castor oil
Empty Capsules
Coloring Agents
Vegetarian Capsules
Soft Gelatin
Digital Content
DATA COMPILATION #PharmaFlow
NEWS #PharmaBuzz
Global Sales Information
Finished Drug Prices
RX/OTC/DISCN : Class B
Dosage Form : Dry Sub C Solv
Dosage Strength :
Price Per Pack (Euro) : 80.9
Published in :
Country : Switzerland
RX/OTC/DISCN : Class B
RX/OTC/DISCN :
Dosage Form : Powder and liquid to the injecti...
Dosage Strength : 8 micro liters/ml
Price Per Pack (Euro) : 77.275
Published in :
Country : Norway
RX/OTC/DISCN :
RX/OTC/DISCN : Class D
Selenium Sulfide; Sulfur Hexafluoride
Dosage Form : Solution
Dosage Strength :
Price Per Pack (Euro) : 5
Published in :
Country : Switzerland
RX/OTC/DISCN : Class D
RX/OTC/DISCN : Class D
Selenium Sulfide; Sulfur Hexafluoride
Dosage Form : Solution
Dosage Strength :
Price Per Pack (Euro) : 9.51
Published in :
Country : Switzerland
RX/OTC/DISCN : Class D
RX/OTC/DISCN : Class H
Dosage Form : Sulfur Hexafluoride, 8Mcl/Ml 5Ml...
Dosage Strength : 8 mcl/ml 1 vial + 1 syringe 5 ml + Adapter
Price Per Pack (Euro) : 101.27
Published in :
Country : Italy
RX/OTC/DISCN : Class H
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14 Oct 2019
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