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Find Clinical Drug Pipeline Developments & Deals by Twist Bioscience
Under the agreement, Twist Biopharma, will leverage its Library of Libraries to conduct antibody discovery campaigns against targets to be determined by Bayer. Bayer will have the option to license antibodies discovered under the collaboration.
Under the terms of the agreement, Twist will utilize the Twist Biopharma Solutions Library of Libraries to conduct research activities to discover novel antibodies against targets identified by Ono for the treatment of autoimmune diseases.
Under the terms of the collaboration, Astellas will license a suite of Twist’s VHH antibody libraries to be used by Astellas for drug discovery and development.
Alpaca-derived VHH antibody is a heavy chain antibody fragment (VHH), anti-SARS-CoV-2 nanobody (saRBD-1), that disrupts spike glycoprotein of SARS-CoV-2 interaction with human ACE 2 by competitively binding to the spike protein receptor-binding domain.
Under the terms of the agreement, Twist will conduct antibody discovery activities against multiple targets of interest to develop curative therapies for patients suffering from diseases that lack treatment options, identified by Astellas.
Under the terms of the agreement, Ildong will license a suite of Twist’s VHH antibody libraries for a period of three years and will use the libraries to conduct research and development activities.
Under the terms of the agreement, the companies will jointly conduct research activities to identify and optimize proprietary Twist antagonist antibodies, targeting an undisclosed checkpoint inhibitor pathway in the tumor microenvironment, as potential therapeutic candidates.
Under the collaboration, Twist will leverage its proprietary Library of Libraries to discover 5 novel antibodies. MediSix will use its platform technologies to develop novel CAR T-cell therapies targeting malignancies and autoimmune diseases without any CAR T-cell fractricide.
Twist Biopharma, expects to leverage its antibody discovery and optimization platform to discover novel antibodies against specific targets of interest that will be engineered into Kriya’s proprietary gene therapy technology platform for durable and targeted delivery.
Twist intends to use the net proceeds of the offering, along with its existing cash, cash equivalents and short-term investments to scale its investment in its research and development organization, which includes investing in pharmaceutical biologics drug discovery.
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