 Drugs in Dev.
 Drugs in Dev.								 Trauma (Emergency, Injury, Surgery)
Trauma (Emergency, Injury, Surgery)
											 IND Enabling
IND Enabling
											
																			 United States %20of America
United States %20of America								
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Lead Product(s) : Entolimod
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Tivic Gets Two INDs For Entolimod In ARS And Advanced Cancers
Details : Entolimod is a novel TLR5 agonist that triggers NF-kB signaling, being investigated for the treatment of acute radiation syndrome and advanced cancers.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
August 20, 2025
Lead Product(s) : Entolimod
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bucillamine
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Revive Therapeutics Advances with Next-Generation Bucillamine Development
Details : Bucillamine, a potent antioxidant and anti-inflammatory, already boasts FDA Orphan Drug Designation for ischemia-reperfusion injury following solid organ transplantation.
Product Name : Undisclosed
Product Type : Amino Acid
Upfront Cash : Inapplicable
June 04, 2025
Lead Product(s) : Bucillamine
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Rusalatide Acetate
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : National Institutes of Health
Deal Size : Undisclosed
Deal Type : Collaboration
Chrysalis Partners with NIAID to Test Chrysalin® for Radiation Injury Treatment
Details : The collaboration aims for evaluating Chrysalin (rusalatide acetate), a regenerative peptide drug, for the treatment of Cutaneous Radiation Injury (CRI).
Product Name : Chrysalin
Product Type : Peptide, Unconjugated
Upfront Cash : Undisclosed
November 18, 2024
Lead Product(s) : Rusalatide Acetate
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : National Institutes of Health
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Bucillamine
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Attwill Medical Solutions
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration aims for the clinical and commercial development of Revive’s lyophilized formulation of Bucillamine, a potent antioxidant and anti-inflammatory and may be helpful for orphan indications in rare inflammatory disorders such as ischemia-...
Product Name : Undisclosed
Product Type : Amino Acid
Upfront Cash : Undisclosed
December 18, 2023
Lead Product(s) : Bucillamine
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Attwill Medical Solutions
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : OWL-1410
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Owl Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the collaboration, Owl Therapeutics will advance Abliva's clinical development of NeuroSTAT (OWL-1410) with orphan drug designation, which is under development for the prevention and treatment of moderate to severe traumatic brain injury (TBI).
Product Name : NeuroSTAT
Product Type : Peptide, Unconjugated
Upfront Cash : Undisclosed
November 17, 2023
Lead Product(s) : OWL-1410
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Owl Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Exosome
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ExoPTEN is being developed to be a minimally invasive ExoTherapy for spinal cord injuries (SCI), yielding neuron regeneration and rewiring in traumatically damaged spinal cord.
Product Name : ExoPTEN
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 13, 2023
Lead Product(s) : Exosome
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : STUP-001
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Stand Up Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Details : STUP-001 (AAV-based gene therapy), the innovative GT medication, unties the knot for spinal cord injured patient through motor sensory neuron reprogramming technology. Cell fate conversion using virus transduction system is of great interest in the field...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
December 29, 2022
Lead Product(s) : STUP-001
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Stand Up Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : TT-20
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Perceptive Xontogeny Venture Fund
Deal Size : $35.0 million
Deal Type : Series A Financing
Tellus Therapeutics Announces $35 Million Series A Financing
Details : Tellus’s lead candidate, TT-20, is derived from a class of molecules found in breast milk, which promote the generation of myelin from postnatal neural stem populations.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 13, 2022
Lead Product(s) : TT-20
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Perceptive Xontogeny Venture Fund
Deal Size : $35.0 million
Deal Type : Series A Financing

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Lead Product(s) : Human Amniotic Fluid
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Dermacyte® Amniotic Wound Care Liquid (human amniotic fluid), a cell-free amniotic injection that is being developed under Merakris’ investigational New Drug (IND) approval for would healing.
Product Name : Dermacyte
Product Type : Protein
Upfront Cash : Inapplicable
November 29, 2022
Lead Product(s) : Human Amniotic Fluid
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : LUT017
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : California Institute for Regenerative Medicine
Deal Size : $5.0 million
Deal Type : Funding
Details : The award will allow for the completion of Investigational New Drug enabling studies. Specifically, the funds will be utilized for the manufacturing of LUT017 active pharmaceutical ingredient and the final formulated drug product (LUT017 gel) to supply t...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 24, 2022
Lead Product(s) : LUT017
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : California Institute for Regenerative Medicine
Deal Size : $5.0 million
Deal Type : Funding


 
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