
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
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Details : Qalsody (tofersen) is an oligonucleotide drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Amyotrophic Lateral Sclerosis.
Product Name : Qalsody
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
November 03, 2025

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Lead Product(s) : Tofersen
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Biogen's QALSODY® gets EU approval for rare ALS therapy
Details : Qalsody (tofersen), an ASO designed to bind to SOD1 mRNA to reduce SOD1 protein production. FDA granted accelerated approval for amyotrophic lateral sclerosis having SOD1 gene mutation.
Product Name : Qalsody
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
May 30, 2024
Lead Product(s) : Tofersen
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tofersen
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Biogen's QALSODY® Receives Positive Opinion from CHMP for Genetic ALS Treatment
Details : Qalsody (tofersen) is an antisense oligonucleotide designed to reduce SOD1 protein production, granted accelerated approval by the USFDA for treating amyotrophic lateral sclerosis with SOD1 mutations.
Product Name : Qalsody
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
February 23, 2024
Lead Product(s) : Tofersen
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tofersen
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Qalsody (tofersen) is an antisense oligonucleotide that causes degradation of SOD1 mRNA through binding to SOD1 mRNA, which results in a reduction of SOD1 protein synthesis.
Product Name : Qalsody
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
April 25, 2023
Lead Product(s) : Tofersen
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Biogen Provides Update on FDA Advisory Committee Meeting on Tofersen for SOD1-ALS
Details : BIIB067 (tofersen) is an antisense oligonucleotide which is thought to reduce the production of SOD1 protein and is being evaluated to see if it can potentially slow the fatal progression of SOD1-ALS.
Product Name : Qalsody
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
March 22, 2023

Details : BIIB067 (tofersen) is an antisense oligonucleotide which is thought to reduce the production of SOD1 protein and is being evaluated to see if it can potentially slow the fatal progression of SOD1-ALS.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
March 22, 2023

Biogen Shares Update on FDA Advisory Committee Meeting for Tofersen
Details : BIIB067 (tofersen) is an antisense oligonucleotide which is thought to reduce the production of SOD1 protein and is being evaluated to see if it can potentially slow the fatal progression of SOD1-ALS.
Product Name : Qalsody
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
January 23, 2023

Details : BIIB067 (tofersen) is an antisense drug being evaluated as a treatment of SOD1-ALS. Tofersen is designed to bind to SOD1 mRNA, inducing its degradation by RNase-H to reduce SOD1 protein production.
Product Name : Qalsody
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
December 06, 2022

Biogen Announces FDA’s 3-Month Extension of Review Period for the New Drug Application for Tofersen
Details : BIIB067 (tofersen) is an antisense drug being evaluated for the potential treatment of SOD1-ALS. Tofersen binds to SOD1 mRNA, allowing for its degradation by RNase-H in an effort to reduce synthesis of SOD1 protein production.
Product Name : Qalsody
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
October 17, 2022

Details : BIIB067 (tofersen) is an antisense drug being evaluated for the potential treatment of SOD1-ALS. Tofersen binds and degrades SOD1 mRNA to reduce synthesis of SOD1 protein production. The most common AEs were procedural pain, headache, pain in the arms or...
Product Name : Qalsody
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
September 21, 2022
