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    [{"orgOrder":0,"company":"TenNor Therapeutics","sponsor":"The First Hospital of Jilin University","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"CHINA","productType":"Antibiotic","year":"2023","type":"Inapplicable","leadProduct":"TNP-2092","moa":"Bacterial DNA gyrase | Topoisomerase IV | Bacterial DNA-directed RNA polymerase","graph1":"Hematology","graph2":"Phase I\/ Phase II","graph3":"TenNor Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"TenNor Therapeutics \/ The First Hospital of Jilin University","highestDevelopmentStatusID":"7","companyTruncated":"TenNor Therapeutics \/ The First Hospital of Jilin University"},{"orgOrder":0,"company":"TenNor Therapeutics","sponsor":"The First Hospital of Jilin 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Innovative Medicine","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"CHINA","productType":"Undisclosed","year":"2021","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Discovery Platform","graph3":"TenNor Therapeutics","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"TenNor Therapeutics \/ Johnson & Johnson Innovative Medicine","highestDevelopmentStatusID":"3","companyTruncated":"TenNor Therapeutics \/ Johnson & Johnson Innovative Medicine"}]

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                            01

                            TenNor Therapeutics

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                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Sponsor : First Affiliated Hospital of Xinjiang Medical University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase 1/2 Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Efficacy of TNP-2092 Administ...

                            Details : TNP-2092 is a Antibiotic drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Prosthesis-Related Infections.

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            March 21, 2025

                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : First Affiliated Hospital of Xinjiang Medical University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            TenNor Therapeutics

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                            Lead Product(s) : Rifasutenizol

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            TenNor Reports Phase III Rifasutenizol Success for H. pylori Infection Treatment

                            Details : TNP-2198 (rifasutenizol) is a RNAP inhibitor, small molecule drug candidate which is currently being evaluated for the treatment of Helicobacter pylori infection.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 18, 2024

                            Lead Product(s) : Rifasutenizol

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            TenNor Therapeutics

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                            Lead Product(s) : Rifasutenizol

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : AMR Action Fund

                            Deal Size : $42.1 million

                            Deal Type : Series E Financing

                            DEALS_DEV arrow-down

                            TenNor Raises 300M RMB for Rifasutenizol Development in Heliobacter Pylori

                            Details : The proceeds will fund the development and to seek regulatory approval in China of TNP-2198 (rifasutenizol), which could become the first drug developed specifically for Helicobacter pylori infection.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            October 16, 2024

                            Lead Product(s) : Rifasutenizol

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : AMR Action Fund

                            Deal Size : $42.1 million

                            Deal Type : Series E Financing

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                            04

                            TenNor Therapeutics

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                            Lead Product(s) : Midazolam

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Drug-Drug Interactions Between TNP-2198 and Midazolam, Clarithromycin

                            Details : Midazolam is a Controlled Substance drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Helicobacter Infections.

                            Product Name : Undisclosed

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            August 13, 2024

                            Lead Product(s) : Midazolam

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            TenNor Therapeutics

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                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phase 1, Single-Dose and Multiple-Dose Continuous Intravenous Infusions of TNP-2092 for Injection in Healthy C...

                            Details : TNP-2092 is a Antibiotic drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Skin Diseases, Bacterial.

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            May 01, 2024

                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

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                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            The Safety and Tolerability, Pharmacokinetics of TNP-2092 Capsules in Combination With Rabeprazole Sodium Ente...

                            Details : TNP-2092 is a Antibiotic drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Helicobacter Infections.

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            March 29, 2024

                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

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                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : The First Hospital of Jilin University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase 1 Study to Evaluate PK Profile of Multiple Oral Administrations of TNP-2092 Capsules in Healthy Subjec...

                            Details : TNP-2092 is a Antibiotic drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Helicobacter Infections.

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            January 05, 2024

                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : The First Hospital of Jilin University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            TenNor Therapeutics

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                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Hematology

                            Study Phase : Phase I

                            Sponsor : The First Hospital of Jilin University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase 1 Study to Evaluate PK Profile and Food Effects on PK Parameters of TNP-2092 Capsules

                            Details : TNP-2092 is a Antibiotic drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hyperammonemia.

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            December 21, 2023

                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase I

                            Sponsor : The First Hospital of Jilin University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            TenNor Therapeutics

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                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Hematology

                            Study Phase : Phase I/ Phase II

                            Sponsor : The First Hospital of Jilin University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            PK Profile and Preliminary Efficacy of TNP-2092 Capsules in Liver Cirrhosis Patients With Hyperammonemia

                            Details : TNP-2092 is a Antibiotic drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Hyperammonemia.

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            November 18, 2023

                            Lead Product(s) : TNP-2092

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : The First Hospital of Jilin University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

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                            Lead Product(s) : 14-C TNP-2198

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Human Mass Balance and Biotransformation Study of [14C]TNP-2198

                            Details : 14-C TNP-2198 is a Radiolabeled Compounds drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Helicobacter Infections.

                            Product Name : Undisclosed

                            Product Type : Radiolabeled Compound

                            Upfront Cash : Inapplicable

                            November 18, 2023

                            Lead Product(s) : 14-C TNP-2198

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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