

Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Study Phase : Approved FDF
Sponsor : Ardelyx
Deal Size : Inapplicable
Deal Type : Inapplicable
Fosun Pharma Received NMPA Approval for Wan Ti Le (Tenapanor Hydrochloride Tablets)
Details : Wan Ti Le (tenapanor HCl) is a sodium/hydrogen exchanger 3 (NHE3) inhibitor indicated for treatment of chronic kidney disease.
Product Name : Wan Ti Le
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 26, 2025
Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Highest Development Status : Approved FDF
Sponsor : Ardelyx
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Xphozah (tenapanor) is a first-in-class, phosphate absorption inhibitor that has a novel mechanism of action and acts locally in the gut to inhibit the sodium hydrogen exchanger 3 (NHE3), indicated for the treatment of pediatric Hyperphosphatemia.
Product Name : Xphozah
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 15, 2023
Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Approves XPHOZAH® (tenapanor), a First-in-Class Phosphate Absorption Inhibitor
Details : Xphozah (tenapanor) is a first-in-class, phosphate absorption inhibitor that has a novel mechanism of action and acts locally in the gut to inhibit the sodium hydrogen exchanger 3 (NHE3), indicated for the treatment in adult with chronic kidney disease o...
Product Name : Xphozah
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 17, 2023
Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Study Phase : Approved FDF
Sponsor : SLR Capital Partners
Deal Size : Undisclosed
Deal Type : Financing
Details : The financing will support the commercialization of company's two FDA approved products, Ibsrela (tenapanor), for irritable bowel syndrome with constipation, and Xphozah (tenapanor), indicated to reduce serum phosphorus in adults with chronic kidney dise...
Product Name : Xphozah
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 17, 2023
Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Highest Development Status : Approved FDF
Sponsor : SLR Capital Partners
Deal Size : Undisclosed
Deal Type : Financing

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Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Tenapanor for Hyperphosphatemia Approved in Japan
Details : Phozevel (tenapanor) is a first-in-class, phosphate absorption inhibitor that has a novel mechanism of action and acts locally in the gut to inhibit the NHE3, indicated for the treatment improvement of hyperphosphatemia in adult patients with CKD on dial...
Product Name : Phozevel
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 25, 2023
Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Fosun Pharmaceutical
Deal Size : $125.0 million
Deal Type : Licensing Agreement
Ardelyx Announces Acceptance of New Drug Application for Tenapanor for Hyperphosphatemia in China
Details : The agreement provides Fosun Pharma the rights to develop and commercialize Ardelyx's lead product, tenapanor, in China for the treatment of patients with irritable bowel syndrome with constipation and for the treatment of hyperphosphatemia related to ch...
Product Name : Xphozah
Product Type : Miscellaneous
Upfront Cash : $12.0 million
July 13, 2023
Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Fosun Pharmaceutical
Deal Size : $125.0 million
Deal Type : Licensing Agreement

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Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Xphozah (tenapanor) is a first-in-class, phosphate absorption inhibitor that has a novel mechanism of action and acts locally in the gut to inhibit the sodium hydrogen exchanger 3 (NHE3), indicated for the treatment in adult with chronic kidney disease o...
Product Name : Xphozah
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 17, 2023
Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Ardelyx Resubmits New Drug Application to U.S. Food and Drug Administration for XPHOZAH® (tenapanor)
Details : Xphozah (tenapanor) is a first-in-class, phosphate absorption inhibitor that has a novel mechanism of action and acts locally in the gut to inhibit the sodium hydrogen exchanger 3 (NHE3), indicated for the treatment in adult with chronic kidney disease o...
Product Name : Xphozah
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 18, 2023
Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Study Phase : Phase IV
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Ardelyx is developing XPHOZAH® (tenapanor), a novel product candidate to control serum phosphorus in adult patients with CKD on dialysis, which has completed three successful Phase 3 trials.
Product Name : Xphozah
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 16, 2022
Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Highest Development Status : Phase IV
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : XPHOZAH (tenapanor),is an investigational first-in-class phosphate absorption inhibitor, With its unique blocking MOA, XPHOZAH acts locally in gut, reducing phosphate absorption through paracellular pathway, primary pathway of phosphate absorption.
Product Name : Xphozah
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 03, 2022
Lead Product(s) : Tenapanor Hydrochloride
Therapeutic Area : Nephrology
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
