Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : STC-15,Toripalimab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Storm Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Coherus and Storm to Evaluate STC-15 with LOQTORZI In Clinical Collaboration
Details : The collaboration aims to advance the clinical development of STC-15 a METTL3 inhibitor, in combination with Loqtorzi for the treatment of NSCLC.
Product Name : STC-15
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
May 27, 2025
Lead Product(s) : STC-15,Toripalimab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Storm Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : STC-15
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : STC-15 is an oral small molecule that inhibits METTL3, an RNA methyltransferase implicated in oncology and other diseases. STC-15, also inhibits tumor growth through mechanisms like changes in interferon signaling and synergy with T cell checkpoint block...
Product Name : STC-15
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 25, 2023
Lead Product(s) : STC-15
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : An orally bioavailable, highly selective METTL3 inhibitor, STC-15 is the first molecule specifically targeting an RNA methyltransferase enzyme to enter clinical development.
Product Name : STC-15
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 23, 2022
Lead Product(s) : STC-15
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
STORM Therapeutics Selects First-in-Class Clinical Candidate Targeting METTL3
Details : STC-15 is an orally bioavailable, small molecule METTL3 inhibitor targeting an entirely new mechanism of action (modulation of RNA epigenetics) to treat acute myeloid leukaemia (AML) and other solid and haematological cancers.
Product Name : STC-15
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 22, 2020
Lead Product(s) : STC-15
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable