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Find Clinical Drug Pipeline Developments & Deals by Spring Bank Pharmaceuticals
SB 11285 is Spring Bank’s intravenously (IV)-administered STING agonist product candidate that is currently being evaluated in a Phase 1a/1b clinical trial as a monotherapy and in combination with Roche’s PD-L1 checkpoint inhibitor (Tecentriq®).
Safety Review Committee for IV SB 11285 Phase 1a/1b trial recommends dose escalation to next planned monotherapy dose level and initiation of first co-administration dose level with Roche’s PD-L1 checkpoint inhibitor atezolizumab (Tecentriq®).
Trial in progress poster will be presented for the Phase 1a/1b trial of the company’s intravenously-administered STING agonist candidate, SB 11285, at the American Society of Clinical Oncology (ASCO) Annual Meeting.
New clinical collaboration with Roche (SIX:RO, ROG), will explore the co-administration of SB 11285 with Roche’s PD-L1 checkpoint inhibitor Tecentriq in patients with advanced solid tumors.
The company based the decision on safety information after unexpected serious adverse events, including one patient death in its Phase IIb CATALYST trial.