

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : Sotigalimab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Pyxis Oncology
Deal Size : $10.7 million
Deal Type : Acquisition
Pyxis Oncology Successfully Completes Acquisition of Apexigen
Details : Through the acquisition, Pyxis Oncology positions at forefront of Antibody-Drug Conjugate (ADC) development by adding PYX-107 (sotigalimab), a potential best-in-class Phase 2 CD40 agonist in clinical development for liposarcoma, melanoma, and other cance...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
August 23, 2023
Lead Product(s) : Sotigalimab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Pyxis Oncology
Deal Size : $10.7 million
Deal Type : Acquisition

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Lead Product(s) : Sotigalimab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Pyxis Oncology
Deal Size : $16.0 million
Deal Type : Acquisition
Pyxis Oncology to Acquire Apexigen
Details : Through the acquisition, Pyxis Oncology positions at forefront of Antibody-Drug Conjugate (ADC) development by adding APX 005 (sotigalimab), a potential best-in-class Phase 2 CD40 agonist in clinical development for liposarcoma, melanoma, and other cance...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
May 24, 2023
Lead Product(s) : Sotigalimab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Pyxis Oncology
Deal Size : $16.0 million
Deal Type : Acquisition

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Lead Product(s) : Sotigalimab,Doxorubicin Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Brookline Capital Markets
Deal Size : $2.8 million
Deal Type : Private Placement
Apexigen Announces Approximately $2.8 Million Private Placement Financing
Details : The gross proceeds will be used to finance and further support the company’s ongoing Phase 2 clinical study evaluating its CD40 antibody, APX005M (sotigalimab), in combination with doxorubicin in patients with liposarcoma.
Product Name : Sotiga
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
January 24, 2023
Lead Product(s) : Sotigalimab,Doxorubicin Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Brookline Capital Markets
Deal Size : $2.8 million
Deal Type : Private Placement

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Lead Product(s) : Sotigalimab,Carboplatin,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Sotiga (sotigalimab) is a humanized monoclonal antibody that binds CD40 with high affinity and activates antigen presenting cells (dendritic cells, monocytes and B cells) leading to stimulation of cancer-specific T-cell responses leading tumor-specific i...
Product Name : Sotiga
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
January 19, 2023
Lead Product(s) : Sotigalimab,Carboplatin,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Sotigalimab,Doxorubicin Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : APX005M (sotigalimab) is a CD40 agonist that has been designed to reverse the systemic immune suppression that typically affects cancer patients, through the activation of several mechanisms of immune functionality.
Product Name : Sotiga
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 14, 2022
Lead Product(s) : Sotigalimab,Doxorubicin Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Sotigalimab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The combination of intratumoral sotigalimab and systemic pembrolizumab was well-tolerated and demonstrated an improved clinical response rate relative to the standard of care, pembrolizumab monotherapy.
Product Name : Sotiga
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 11, 2022
Lead Product(s) : Sotigalimab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Sotigalimab,Carboplatin,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Sotiga (sotigalimab) in combination with neoadjuvant chemoradiation induced higher pathologic complete response rates, an important predictor of survival, in patients with both adenocarcinoma and squamous cell carcinoma.
Product Name : Sotiga
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
September 10, 2022
Lead Product(s) : Sotigalimab,Carboplatin,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Sotigalimab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Sotigalimab (sotiga), Apexigen’s agonist antibody targeting CD40, in combination with neoadjuvant chemoradiation for patients with resectable esophageal and gastroesophageal junction (GEJ) cancers.
Product Name : Sotiga
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
September 05, 2022
Lead Product(s) : Sotigalimab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Sotigalimab,Paclitaxel,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Bristol Myers Squibb
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : APX005M (Sotigalimab) is a potent CD40 agonist that has been designed to reverse the systemic immune suppression that typically affects cancer patients, through the activation of several mechanisms of immune functionality.
Product Name : Sotiga
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
June 06, 2022
Lead Product(s) : Sotigalimab,Paclitaxel,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Bristol Myers Squibb
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Sotigalimab,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Intratumoral CD40 agonist APX005M (sotigalimab) with pembrolizumab induces broad innate and adaptive immune activation in local and distant tumors in metastatic melanoma.
Product Name : Sotiga
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
April 07, 2022
Lead Product(s) : Sotigalimab,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
