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2024","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase I"},{"orgOrder":0,"company":"SAB Biotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"SAB Biotherapeutics Announces Commencement of the HUMAN Phase 1 Clinical Trial with SAB-142, a Potential Disease-Modifying Treatment for Type 1 Diabetes","therapeuticArea":"Endocrinology","highestDevelopmentStatus":"Phase I","country":"U.S.A","productType":"Large molecule","productStatus":"New Molecular Entity","date":"November 2023","url1":"","url2":"","graph1":"Endocrinology","graph2":"Phase I"},{"orgOrder":0,"company":"SAB Biotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"SAB Biotherapeutics Provides SAB-142 Trial Update","therapeuticArea":"Endocrinology","highestDevelopmentStatus":"Phase I","country":"U.S.A","productType":"Large 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Find Clinical Drug Pipeline Developments & Deals by SAB Biotherapeutics
SAB Biotherapeutics lead product candidate SAB-142, which is an anti-thymocyte globulin. Currently being evaluated in the early stage trial studies for the treatment of type 1 diabetes.
The partnership aims to evaluate SAB-176, a fully human polyclonal antibodies targeting influenza from Transchromosomic (Tc) Bovine, being investigated for use as a pre- and post-exposure prophylactic treatment for influenza type A and type B.
SAB-142 is a CD2/CD3/CD4/CD8/CD154 Binder antibody drug, which is being investigated for the management of Type 1 Diabetes, as an intravenous infusion.
The financing will be used to fund the development of the company’s lead research program, SAB-142, a fully-human alternative to rabbit anti-thymocyte globulin and a potential disease modifying treatment for type 1 diabetes (T1D).
SAB-142 is the first fully-human anti-thymocyte hpAB therapeutic currently being developed for delaying the progression and onset of type 1 diabetes, among other autoimmune indications.
SAB will use the funds to clinically advance SAB-142, a fully-human alternative to rabbit anti-thymocyte globulin (rATG), its lead therapeutic candidate for type 1 diabetes (T1D).
SAB-185 is a fully human polyclonal antibody therapeutic, represents a highly-differentiated treatment option that provides a highly-specific match against the complexity, diversity, and the mutations SARS-CoV-2 presents.
SAB-176 is the first fully-human broadly neutralizing immunoglobulin antibody therapeutic intended to prevent or reduce severe outcomes of Type A and Type B influenza infection.
SAB-176 is the first fully-human broadly neutralizing immunoglobulin antibody therapeutic intended to prevent or reduce severe outcomes of Type A and Type B influenza infection.
SAB-185, a fully human polyclonal antibody therapeutic, represents a highly-differentiated treatment option that provides a highly-specific match against the complexity, diversity, and the mutations SARS-CoV-2 presents.
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