Lead Product(s) : Ruxotemitide,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Lytix Biopharma
Deal Size : Inapplicable
Deal Type : Inapplicable
NeoLIPA: Neoadjuvant LTX-315 in Combination with Pembrolizumab in Resectable Stage III/IV Melanoma
Details : Undisclosed
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
October 21, 2024
Lead Product(s) : Ruxotemitide,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Lytix Biopharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Verrica Announces Positive Results for Phase 2 Study of VP-315 in Basal Cell Carcinoma
Details : VP-315 (ruxotemitide)is a potential first-in-class oncolytic peptide to induce immunogenic cell death. It is under phase 2 clinical development for the treatment of Basal Cell Carcinoma.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
August 14, 2024
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Verrica Doses Last Patient in Phase 2 Study Of VP-315 for Skin Cancer
Details : VP-315 (ruxotemitide) is an oncolytic peptide immunotherapy in Phase 2, aiming to treat basal cell carcinoma by inducing immunogenic cell death.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
May 01, 2024
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : VP-315 (ruxotemitide, formerly known as LTX 315) is a potential first-in-class oncolytic peptide immunotherapy administered directly into a tumor to induce immunogenic cell death, which may offer a non-surgical option for patients suffering from skin can...
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
December 04, 2023
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Undisclosed
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The trial demonstrated that combination of LTX-315 and ACT is feasible and tolerable, and that CD4+ and CD8+ T cells can be expanded in vitro from STS that have been pretreated with the oncolytic molecule LTX-315.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
May 27, 2022
Lead Product(s) : Ruxotemitide,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Verrica Pharmaceuticals
Deal Size : $111.0 million
Deal Type : Licensing Agreement
Details : Verrica, has an exclusive license agreement with Lytix to develop and commercialize LTX-315 for skin cancer conditions. LTX-315 is a first-in-class oncolytic peptide derived from human lactoferrin, with potential lytic and immunostimulating activities.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Undisclosed
May 04, 2022
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Verrica Pharmaceuticals
Deal Size : $111.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LTX-315, a potential first-in-class oncolytic peptide directly targets cancerous skin cells to induce an anti-tumor immune response, providing a potential alternative to surgery, for the treatment of basal cell carcinoma.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
May 04, 2022
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Tumor Infiltrating Lymphocyte
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lytix Biopharma to Present at the American Society of Clinical Oncology (ASCO) Annual Meeting
Details : LTX-315 is a potential first-in-class oncolytic molecule administered directly into a tumor to induce immunogenic cell death, which also has demonstrated positive tumor-specific immune cell responses in multi-indication Phase I/II oncology trials.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
April 28, 2022
Lead Product(s) : Ruxotemitide,Tumor Infiltrating Lymphocyte
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Instat Clinical Research | HeartcoR Solutions | Myonex | Vial
Deal Size : Inapplicable
Deal Type : Inapplicable
Open-Label Proof of Concept Study of VP-315 in Basal Cell Carcinoma
Details : Undisclosed
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
January 12, 2022
Lead Product(s) : Ruxotemitide,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Instat Clinical Research | HeartcoR Solutions | Myonex | Vial
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ruxotemitide,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : LabCorp | OWL
Deal Size : Inapplicable
Deal Type : Inapplicable
Intratumoral Injection of LTX-315 in Combination With Pembrolizumab in Advanced Melanoma
Details : Undisclosed
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
March 12, 2021
Lead Product(s) : Ruxotemitide,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : LabCorp | OWL
Deal Size : Inapplicable
Deal Type : Inapplicable