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              Takeda Pharmaceutical

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              CAMBODIA PHAR-MED 2020

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              Takeda Partners up with Carmine Therapeutics to Develop and Market Rare Disease Candidates

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              Lead Product(s): RBCEV-based gene therapy

              Therapeutic Area: Rare Diseases and Disorders Product Name: Undisclosed

              Highest Development Status: Discovery Product Type: Cell and Gene therapy

              Partner/Sponsor/Collaborator: Carmine Therapeutics

              Deal Size: $900.0 million Upfront Cash: Undisclosed

              Deal Type: Collaboration June 30, 2020

              Details:

              The collaboration will leverage Carmine’s REGENT technology, which is based on red blood cell extracellular vesicles, allowing for repeat dosing, enhanced bio-distribution and larger transgene payload capacity compared to adeno-associated virus-based gene therapy.

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