

Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : ATAI Life Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PCN-101 (R-ketamine), a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, is a single isomer of ketamine and belongs to a new generation of glutamate receptor modulators with the potential for rapid-acting antidepressant activity and anti-...
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
August 08, 2023
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : ATAI Life Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PCN-101 is a single isomer of ketamine and belongs to a new generation of glutamate receptor modulators with the potential for rapid-acting antidepressant activity and anti-suicidal effects. Pharmacologically, PCN-101 is a non-competitive NMDA receptor a...
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
April 13, 2023
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Otsuka Pharmaceutical
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PCN-101 (R-ketamine), demonstrated an encouraging safety profile and signals of efficacy across all timepoints despite not achieving statistical significance on the primary endpoint.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
January 06, 2023
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Otsuka Pharmaceutical
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PCN-101 (R-ketamine) is a single isomer of ketamine and belongs to a new generation of glutamate receptor modulators with the potential for rapid-acting antidepressant (RAAD) activity and anti-suicidal effects.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
November 17, 2022
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PCN-101 is a single isomer of ketamine and belongs to a new generation of glutamate receptor modulators with the potential for rapid-acting antidepressant (RAAD) activity and anti-suicidal effects. Pharmacologically, PCN-101 is a non-competitive NMDA rec...
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
October 25, 2022
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Precision For Medicine | IQVIA
Deal Size : Inapplicable
Deal Type : Inapplicable
A Randomized, Placebo-Controlled, Double-Blind Study to Assess Safety and Efficacy of PCN-101 in TRD
Details : PCN-101 is a Controlled Substance drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Depressive Disorder, Treatment-Resistant.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
June 10, 2022
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Precision For Medicine | IQVIA
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Apeiron Investment Group
Deal Size : Undisclosed
Deal Type : Agreement
Details : In the aggregate, these renewed lock-up agreements represent over 30% of atai’s outstanding common shares and illustrate the confidence of atai’s key shareholders in atai’s platform and its potential to address the growing mental health crisis incl...
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Undisclosed
December 15, 2021
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Apeiron Investment Group
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Company initiate, Phase 2a clinical study to evaluate the safety and efficacy of PCN-101 (R-ketamine), a stereoisomer of ketamine being developed for therapeutic treatment of psychiatric disorders such as TRD.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
September 14, 2021
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : ATAI Life Sciences
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Integration of Introspect’s digital therapeutic with R-ketamine therapy for patients with treatment resistant depression.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Undisclosed
September 09, 2021
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : ATAI Life Sciences
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Otsuka Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration
Perception and Otsuka Enter Collaboration and Licensing Deal for Depression Drug Candidate
Details : Under the terms of the license, Otsuka will have exclusive rights to develop and commercialize products containing PCN-101 in Japan. Otsuka will undertake development, regulatory, and commercialization activities in Japan, with input and guidance from bo...
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : $20.0 million
March 16, 2021
Lead Product(s) : R-Ketamine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Otsuka Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration
