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Find Novel Psychiatry/Psychology Drugs in Preclinical Development in UNITED STATES

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            Lead Product(s): Psilocybine

            Therapeutic Area: Psychiatry/Psychology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: University of Toronto

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration October 01, 2020

            Details:

            The study will bring new scientific understanding to psilocybin metabolism in the mammalian body and how low-dose psilocybin affects mental health conditions such as depression and anxiety.

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            Lead Product(s): FT-104

            Therapeutic Area: Psychiatry/Psychology Product Name: FT-104

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 29, 2020

            Details:

            FT-104 is designed to provide unique and useful pharmacological features to make a commercially viable alternative to naturally derived substances such as psilocybin, DMT and LSD.

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            Lead Product(s): Psilocin

            Therapeutic Area: Psychiatry/Psychology Product Name: MSP-1001

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 31, 2020

            Details:

            Mindset has conducted several pharmacological tests on its proprietary synthesized compounds, including a gold-standard functional assay to determine its molecules' functional activity at the human 5HT-2A receptor and other serotonin subtypes.

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            Lead Product(s): ALID-10

            Therapeutic Area: Psychiatry/Psychology Product Name: ALID-10

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 31, 2020

            Details:

            The patent application covers Allied’s proprietary products, ALID-10 and ALID-11, as well as other novel cannabis derived compounds designed for superior pharmaceutical properties for treatment of PTSD and other mental disorders.

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            Lead Product(s): Oxytocin

            Therapeutic Area: Psychiatry/Psychology Product Name: TNX-1900

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 04, 2020

            Details:

            The data show that intranasal oxytocin, but not intravenous oxytocin or vehicle, attenuated both reactive and spontaneous pain following mild traumatic brain injury in an animal model.

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            Lead Product(s): Naltrexone

            Therapeutic Area: Psychiatry/Psychology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable May 22, 2020

            Details:

            In light of uncertainties across many industries due to COVID-19, BioCorRx wanted to reiterate that its pivotal GLP preclinical studies of BICX102, continue to progress and have been uninterrupted by COVID-19 to date.

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            Lead Product(s): Cannabidiol,Tetramethylpyrazine

            Therapeutic Area: Psychiatry/Psychology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable May 12, 2020

            Details:

            The U.S. Patent and Trademark Office has issued a “composition of matter” patent with claims covering ART12.11, the Company’s cocrystal, solid form of CBD (cannabidiol) and TMP (tetramethypyrazine).

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            Lead Product(s): Naltrexone

            Therapeutic Area: Psychiatry/Psychology Product Name: BICX102

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: BioCorRx

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Partnership February 26, 2020

            Details:

            Irisys is providing contract development and GMP manufacturing services to BioCorRx Pharmaceuticals for a sterile naltrexone sub-cutaneous implant (BICX102) used in treatment of opioid use disorder and the prevention of relapse following opioid detoxification.

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            Lead Product(s): Naltrexone

            Therapeutic Area: Psychiatry/Psychology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: National Institute on Drug Abuse

            Deal Size: $5.7 million Upfront Cash: Undisclosed

            Deal Type: Funding January 30, 2020

            Details:

            The grant was awarded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH). The grant is for the development of BICX102.

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            Lead Product(s): Drinabant

            Therapeutic Area: Psychiatry/Psychology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: National Center for Advancing Translational Sciences

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration January 02, 2020

            Details:

            NCATS will provide development resources and funding around certain pre-clinical activities and studies in order to support Opiant’s planned filing of an IND application for OPNT004.

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