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Find Clinical Drug Pipeline Developments & Deals by Pliant Therapeutics
PLN-74809 (bexotegrast) is an oral, small molecule, dual-selective inhibitor of αvβ6 and αvβ1 integrins, which is being evaluated for the treatment of Idiopathic Pulmonary Fibrosis.
PLN-74809 (bexotegrast) is an oral, small molecule, dual-selective inhibitor of the αvβ6 and αvβ1 integrins. It is being evaluated in phase 2 clinial trials for the treatment of primary sclerosing cholangitis & suspected moderate to severe liver fibrosis.
PLN-74809 (bexotegrast), is an oral small molecule dual selective inhibitor of αvß6 and αvß1 integrins that is in development in the lead indications for the treatment of idiopathic pulmonary fibrosis, or IPF, and primary sclerosing cholangitis, or PSC.
PLN-74809 (bexotegrast), is an oral small molecule dual selective inhibitor of αvß6 and αvß1 integrins that is in development in the lead indications for the treatment of idiopathic pulmonary fibrosis, or IPF, and primary sclerosing cholangitis, or PSC.
PLN-74809 (bexotegrast), is an oral small molecule dual selective inhibitor of αvß6 and αvß1 integrins that is in development in the lead indications for the treatment of idiopathic pulmonary fibrosis and primary sclerosing cholangitis.
PLN-74809 (bexotegrast), is an oral small molecule dual selective inhibitor of αvß6 and αvß1 integrins that is in development in the lead indications for the treatment of idiopathic pulmonary fibrosis, or IPF, and primary sclerosing cholangitis, or PSC.
The new strategy focusing on a limited number of therapeutic areas, to divest clinical NASH assets and, as a result, to discontinue the development of PLN-1474, a small molecule selective inhibitor of integrin αvß1, for the treatment of liver fibrosis associated with NASH.
PLN-101095, a small molecule, which targets αvβ8 and αvβ1 integrins expressed in the tumor microenvironment, regulating TGF-β activation with the goal of re-sensitizing tumors to PD(L)-1 inhibitors.
Pliant intends to use the net proceeds to develop its ongoing and future preclinical and clinical programs including PLN-74809 (bexotegrast) and PLN-101095, further develop its integrin targeting platform, to fund working capital and for other general corporate purposes.
Pliant intends to use the net proceeds to develop its ongoing and future preclinical and clinical programs including PLN-74809 (bexotegrast) and PLN-101095, further develop its integrin targeting platform, to fund working capital and for other general corporate purposes.
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