

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : Tovorafenib,Pimasertib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : DAY101 (Tovorafenib) is an investigational, oral, brain-penetrant, highly-selective type II pan-RAF kinase inhibitor designed to target a key enzyme in the MAPK signaling pathway, which is being investigated in primary brain tumors or brain metastases of...
Product Name : Ojemda
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 23, 2022
Lead Product(s) : Tovorafenib,Pimasertib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tovorafenib,Pimasertib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Day One Announces First Patient Dosed in Phase 2 Monotherapy Study in RAF-altered Solid Tumors
Details : DAY101 has demonstrated encouraging anti-tumor activity as a monotherapy in patient populations where MAPK pathway alterations are believed to play an important role in driving disease progression.
Product Name : Ojemda
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 22, 2021
Lead Product(s) : Tovorafenib,Pimasertib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pimasertib,Tovorafenib
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Day One Biopharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Day One Expands Clinical-Stage Oncology Pipeline; Announces Global License Agreement with Merck KGaA
Details : Exclusive license agreement broadens Day One’s clinical-stage pipeline of targeted cancer therapies with the additions of pimasertib and MSC2015103B. Day One plans to study the combination of pimasertib and DAY101 in patients ≥12 years of age with ad...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
February 23, 2021
Lead Product(s) : Pimasertib,Tovorafenib
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Day One Biopharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : Pimasertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Relative Bioavailability of Pimasertib in Cancer Patients
Details : Pimasertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 25, 2013
Lead Product(s) : Pimasertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pimasertib,SAR245409
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Sanofi
Deal Size : Inapplicable
Deal Type : Inapplicable
Trial of Pimasertib With SAR245409 or Placebo in Ovarian Cancer
Details : Pimasertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Ovarian Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 06, 2013
Lead Product(s) : Pimasertib,SAR245409
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Sanofi
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pimasertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Oral Bioavailability and Mass Balance Trial With Pimasertib
Details : Pimasertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 24, 2012
Lead Product(s) : Pimasertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pimasertib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Merck Group
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase II Trial of Pimasertib Versus Dacarbazine in N-Ras Mutated Cutaneous Melanoma
Details : Pimasertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Melanoma, Cutaneous Malignant.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 26, 2012
Lead Product(s) : Pimasertib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Merck Group
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pimasertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Merck Group
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Pimasertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 17, 2012
Lead Product(s) : Pimasertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Merck Group
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pimasertib,SAR245409
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Sanofi
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Pimasertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 11, 2011
Lead Product(s) : Pimasertib,SAR245409
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Sanofi
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pimasertib,Temsirolimus
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus
Details : Pimasertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 22, 2011
Lead Product(s) : Pimasertib,Temsirolimus
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
