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Find Clinical Drug Pipeline Developments & Deals for Ozanimod
Zeposia (ozanimod) is an oral, sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity to S1P receptors 1 and 5. It is being evaluated for the treatment of Crohn’s disease.
Zeposia (ozanimod) is an oral, sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity to S1P receptors 1 and 5. It is indicated for the treatment of relapsing forms of multiple sclerosis.
Zeposia (ozanimod) is an oral, sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity to S1P receptors 1 and 5. Zeposia blocks the capacity of lymphocytes to egress from lymph nodes, reducing the number of lymphocytes in peripheral blood.
Zeposia (ozanimod) is an oral, sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity to S1P receptors 1 and 5 also maintains disease control even in the event of temporary treatment interruption for up to eight weeks.
Results showed improved or preserved cognitive function in a majority of people for Zeposia (ozanimod hydrochloride) with greatest effect observed in almost 80% of people with high thalamic volume at Month 48 of DAYBREAK open-label extension trial.
Zeposia is oral S1P receptor modulator for Ulcerative Colitis. Its approval is based on the Phase 3 True North trial, which demonstrated clinically meaningful improvements in key clinical, endoscopic and mucosal healing endpoints, with no new safety signals observed.
Zeposia (ozanimod) is an oral, sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity to S1P receptors 1 and 5 used for treatment of Relapsing forms of multiple sclerosis (MS) and ulcerative colitis (UC) in adults.
The approval is based on data from True North, a pivotal Phase 3 trial evaluating Zeposia as an induction and maintenance therapy versus placebo in adult patients with moderately to severely active ulcerative colitis.
True North is a Phase 3, multicenter, randomized, double-blind, placebo-controlled trial comparing the efficacy and safety of Zeposia (ozanimod) 1mg in patients with moderately to severely active ulcerative colitis who did not adequately respond to prior treatment.
The sNDA submitted to the FDA is based on results from True North, a pivotal, placebo-controlled Phase 3 trial evaluating Zeposia as an induction and maintenance therapy in adults with moderately to severely active UC.
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