Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed,Inapplicable
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : F. Hoffmann-La Roche
Deal Size : $1,036.0 million
Deal Type : Collaboration
Oxford BioTherapeutics, Roche Partner to Discover Novel Cancer Targets
Details : The collaboration of OBT with Roche to discover novel potentially first-in-class antibody-based therapeutics for the treatment of cancer.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : $36.0 million
March 19, 2025
Lead Product(s) : Undisclosed,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : F. Hoffmann-La Roche
Deal Size : $1,036.0 million
Deal Type : Collaboration
Lead Product(s) : Undisclosed,Inapplicable
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Boehringer Ingelheim Acquires License for Novel Antibody Cancer Treatments
Details : Under the expanded collaboration agreement, Boehringer Ingelheim will be responsible for the future development and commercialization of antibody products for the Cancer.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
January 09, 2025
Lead Product(s) : Undisclosed,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Oxford Doses First Patient with OBT076 in Phase 1b Trial for Head and Neck Cancers
Details : OBT076 is a experimental CD205/Ly75-directed ADC which is currently being evaluated in phase 1 clinical trials for the treatment of Adenoid Cystic Carcinoma of the Head and Neck.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
January 18, 2024
Lead Product(s) : BI 764532,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : OBT620 (BI 764532) is an investigational DLL3/CD3 IgG-like T-cell engager for potential treatment of patients with advanced or metastatic large-cell neuroendocrine carcinoma of the lung.
Product Name : Undisclosed
Product Type : Other Large Molecule
Upfront Cash : Inapplicable
November 29, 2023
Lead Product(s) : BI 764532,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : BI 764532,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BI 764532 is an investigational T-cell engager that redirects T cells towards cancer cells expressing the DLL3 protein, which is investigated for the treatment of small cell lung cancer and extrapulmonary neuroendocrine cancers.
Product Name : Undisclosed
Product Type : Other Large Molecule
Upfront Cash : Inapplicable
October 24, 2023
Lead Product(s) : BI 764532,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : OBT620,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Details : Under the extended agreement, Boehringer is responsible for the development and commercialization of candidates, including OBT620, that interact with the novel targets identified by OBT’s proprietary OGAP® discovery platform for Boehringer’s immuno-...
Product Name : Undisclosed
Product Type : Other Large Molecule
Upfront Cash : Undisclosed
May 25, 2023
Lead Product(s) : OBT620,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Details : OBT076 targets the CD205 receptor on tumor cells as well as certain immune suppressive cells in Combination with CPI Balstilimab for patients with advanced solid tumors.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
May 07, 2023
Details : The collaboration aims to investigate OBT076, an ADC utilizing an ImmunoGen toxin in patients with Adenoid Cystic Carcinoma (ACC) of the head and neck. The trial will investigate OBT076 as monotherapy and in sequence with balstilimab.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Undisclosed
April 19, 2023
Lead Product(s) : BI 764532,Inapplicable
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BI 764532 is an investigational T-cell engager that redirects T cells towards cancer cells expressing the DLL3 protein, which is investigated for the treatment of Small Cell Lung Cancer and Extrapulmonary Neuroendocrine Cancers.
Product Name : Undisclosed
Product Type : Other Large Molecule
Upfront Cash : Inapplicable
February 10, 2023
Lead Product(s) : BI 764532,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Initial data from the Phase 1 dose escalation part of the OBT076 (MEN1309) trial in adult patients with advanced solid tumors indicated that OBT076 had a favorable tolerability profile; recommended dose was defined at 3.0 mg/kg.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
July 04, 2022