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    Find Novel Oncology Drugs in Clinical Development in NETHERLANDS

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              Synaffix

              • Deals

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              NETHERLANDS Netherlands

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              CAMBODIA PHAR-MED 2020

              Participation Not Confirmed

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              Synaffix Announces Expansion of Collaboration with ADC Therapeutics

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              Lead Product(s): Antibody-drug conjugates

              Therapeutic Area: Oncology Product Name: Undisclosed

              Highest Development Status: Undisclosed Product Type: Large molecule

              Partner/Sponsor/Collaborator: ADC Therapeutics

              Deal Size: $54.0 million Upfront Cash: Undisclosed

              Deal Type: Collaboration July 23, 2020

              Details:

              Under the expanded collaboration, ADC Therapeutics has been granted non-exclusive rights for two additional programs, which brings the total number of programs using Synaffix’ ADC technologies to five.

              Lava Therapeutics

              • Deals

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              NETHERLANDS Netherlands

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              CAMBODIA PHAR-MED 2020

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              Lava Therapeutics Announces Collaboration with Janssen to Develop Bi-specific Gamma-Delta T-cell Engager Therapeutics

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              Lead Product(s): Vγ9Vδ2 T cells based antibodies

              Therapeutic Area: Oncology Product Name: Undisclosed

              Highest Development Status: Undisclosed Product Type: Large molecule

              Partner/Sponsor/Collaborator: Johnson & Johnson

              Deal Size: Undisclosed Upfront Cash: Undisclosed

              Deal Type: Collaboration May 15, 2020

              Details:

              Lava Therapeutics will perform discovery and product development activities, and is eligible to receive an undisclosed financial package consisting of an upfront payment and potential development and commercial milestones, and future tiered royalties.

              Kiadis Pharma

              • Development Update

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              NETHERLANDS Netherlands

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              CAMBODIA PHAR-MED 2020

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              Kiadis Pharma Files First Investigational New Drug Application with The U.S. FDA for Natural Killer Cell Therapy

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              Lead Product(s): K-NK002

              Therapeutic Area: Oncology Product Name: Undisclosed

              Highest Development Status: Undisclosed Product Type: Cell and Gene therapy

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable April 09, 2020

              Details:

              IND supports the Company’s planned NK-REALM Phase 1/2 study which will evaluate K-NK002 in 63 patients with blood cancer undergoing a haploidentical hematopoietic stem cell transplant (HSCT).

              Lava Therapeutics

              • Deals

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              NETHERLANDS Netherlands

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              CAMBODIA PHAR-MED 2020

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              ProBioGen, Lava Therapeutics Sign Cell Line Mfg. Pact

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              Lead Product(s): Vγ9Vδ2 T cells based antibodies

              Therapeutic Area: Oncology Product Name: Undisclosed

              Highest Development Status: Undisclosed Product Type: Large molecule

              Partner/Sponsor/Collaborator: ProBioGen

              Deal Size: Undisclosed Upfront Cash: Undisclosed

              Deal Type: Agreement January 14, 2020

              Details:

              Under the agreement and using its CHO.RiGHT™ expression platform, ProBioGen will conduct cell line development of a ?? T-cell engaging bispecific antibody format.

              Synaffix

              • Deals

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              NETHERLANDS Netherlands

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              CAMBODIA PHAR-MED 2020

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              Synaffix announces expansion of license agreement with Shanghai Miracogen Inc. to a second ADC candidate

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              Lead Product(s): Antibody drug conjugate linker

              Therapeutic Area: Oncology Product Name: Undisclosed

              Highest Development Status: Undisclosed Product Type: Undisclosed

              Partner/Sponsor/Collaborator: Shanghai Miracogen

              Deal Size: Undisclosed Upfront Cash: Undisclosed

              Deal Type: Licensing Agreement January 07, 2020

              Details:

              Miracogen has been granted non-exclusive rights to Synaffix’s proprietary GlycoConnect™ and HydraSpace™ ADC technologies for use in this second clinical candidate.

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